Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Lindsey N. Williams"'
Autor:
Jesse J. Salk, Kaitlyn Loubet-Senear, Elisabeth Maritschnegg, Charles C. Valentine, Lindsey N. Williams, Jacob E. Higgins, Reinhard Horvat, Adriaan Vanderstichele, Daniela Nachmanson, Kathryn T. Baker, Mary J. Emond, Emily Loter, Maria Tretiakova, Thierry Soussi, Lawrence A. Loeb, Robert Zeillinger, Paul Speiser, Rosa Ana Risques
Publikováno v:
Cell Reports, Vol 28, Iss 1, Pp 132-144.e3 (2019)
Summary: High-accuracy next-generation DNA sequencing promises a paradigm shift in early cancer detection by enabling the identification of mutant cancer molecules in minimally invasive body fluid samples. We demonstrate 80% sensitivity for ovarian c
Externí odkaz:
https://doaj.org/article/321fc6803f4e46e7a0f6986070caf555
Autor:
Alan J. Herr, Masanori Ogawa, Nicole A. Lawrence, Lindsey N. Williams, Julie M. Eggington, Mallika Singh, Robert A. Smith, Bradley D. Preston
Publikováno v:
PLoS Genetics, Vol 7, Iss 11 (2011)
Externí odkaz:
https://doaj.org/article/886f8382d03c464392dcdc6ca93da736
Autor:
Stephanie L. Smith-Roe, Cheryl A. Hobbs, Victoria Hull, J. Todd Auman, Leslie Recio, Michael A. Streicker, Miriam V. Rivas, Gabriel A. Pratt, Fang Yin Lo, Jacob E. Higgins, Elizabeth K. Schmidt, Lindsey N. Williams, Daniela Nachmanson, Charles C. Valentine, Jesse J. Salk, Kristine L. Witt
Publikováno v:
bioRxiv
Duplex sequencing (DuplexSeq) is an error-corrected next-generation sequencing (ecNGS) method in which molecular barcodes informatically link PCR-copies back to their source DNA strands, enabling computational removal of errors by comparing grouped s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc6e7afac422b90213086f574be3047
https://doi.org/10.1101/2023.05.08.539833
https://doi.org/10.1101/2023.05.08.539833
Autor:
Elizabeth K. Schmidt, Roberta A. Mittelstaedt, Timothy W. Robison, Xuefei Cao, Ying Chen, Wei Sun, Rebecca Wynne, Yiying Wang, Levan Muskhelishvili, Charles C. Valentine, Thomas H. Smith, Lindsey N. Williams, Zachary K Norgaard, Robert H. Heflich, Kelly Davis, Jesse J. Salk, Jeffry Yaplee
Publikováno v:
Environmental and Molecular Mutagenesis
The organotypic human air‐liquid‐interface (ALI) airway tissue model has been used as an in vitro cell culture system for evaluating the toxicity of inhaled substances. ALI airway cultures are highly differentiated, which has made it challenging
Autor:
Lindsey N. Williams, Charles C. Valentine, Rohan Kulkarni, Jesse J. Salk, Robert R. Young, Mark R. Fielden, Tan Li, Sheroy Minocherhomji
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Error-corrected next-generation sequencing (ecNGS) can be used to rapidly detect and quantify the in vivo mutagenic impact of environmental exposures or endogenous processes in any tissue, from any species, at any genomic location. The g
Autor:
Jesse J. Salk, Rohan Kulkarni, Tan Li, Charles C. Valentine, Robert R. Young, Sheroy Minocherhomji, Mark R. Fielden, Lindsey N. Williams
The ability to accurately measure mutations is critical for basic research and identification of potential drug and chemical carcinogens. Current methods for in vivo quantification of mutagenesis are limited because they rely on transgenic rodent sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95d3e925b5ca7bb1ee0b6af874663f00
https://doi.org/10.1101/2020.06.28.176685
https://doi.org/10.1101/2020.06.28.176685
Autor:
Rebecca Garris, Jesse J. Salk, Gabriel Pratt, Lindsey N. Williams, Victor M. Rivera, Jerald P. Radich, Marina Konopleva, Rashmi Kanagal-Shamanna, Koji Sasaki, Nicholas J. Short, Hagop M. Kantarjian, Jorge E. Cortes, Ghayas C. Issa, Guillermo Garcia-Manero, Farhad Ravandi, Justin R. Pritchard, Elias Jabbour, Steven M. Kornblau, Jake Higgins, Charles C. Valentine
Publikováno v:
Blood Cancer Journal, Vol 10, Iss 5, Pp 1-9 (2020)
Blood Cancer Journal
Blood Cancer Journal
Mutations of ABL1 are the dominant mechanism of relapse in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph + ALL). We performed highly accurate Duplex Sequencing of exons 4–10 of ABL1 on bone marrow or peripheral blood samples fro
Autor:
Charles C. Valentine, Rhonda E. Ries, Fang Yin Lo, Benjamin J. Huang, Michael J. Hipp, Lindsey N. Williams, Soheil Meshinchi, Jacob Higgins, Jesse J. Salk, Amanda R. Leonti, Jerald P. Radich
Publikováno v:
Blood. 136:31-32
Sensitive and specific detection of measurable residual disease (MRD) after treatment in pediatric acute myeloid leukemia (AML) is prognostic of relapse and is important for clinical decision making. Mutation-based methods are increasingly being used
Autor:
Robert Zeillinger, Jesse J. Salk, Charles C. Valentine, Thierry Soussi, Elisabeth Maritschnegg, Lindsey N. Williams, Jacob Higgins, Mary J. Emond, Kaitlyn Loubet-Senear, Adriaan Vanderstichele, Lawrence A. Loeb, Reinhard Horvat, Kathryn T. Baker, Rosa Ana Risques, Paul Speiser, Daniela Nachmanson, Maria S. Tretiakova, Emily Loter
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2019, 28 (1), pp.132-144.e3. ⟨10.1016/j.celrep.2019.05.109⟩
Cell Reports, Vol 28, Iss 1, Pp 132-144.e3 (2019)
Cell Reports, 2019, 28 (1), pp.132-144.e3. ⟨10.1016/j.celrep.2019.05.109⟩
Cell Reports, Elsevier Inc, 2019, 28 (1), pp.132-144.e3. ⟨10.1016/j.celrep.2019.05.109⟩
Cell Reports, Vol 28, Iss 1, Pp 132-144.e3 (2019)
Cell Reports, 2019, 28 (1), pp.132-144.e3. ⟨10.1016/j.celrep.2019.05.109⟩
Summary: High-accuracy next-generation DNA sequencing promises a paradigm shift in early cancer detection by enabling the identification of mutant cancer molecules in minimally invasive body fluid samples. We demonstrate 80% sensitivity for ovarian c
Autor:
Elisabeth Maritschnegg, Thierry Soussi, Reinhard Horvat, Paul Speiser, Mary J. Emond, Rosa Ana Risques, Daniela Nachmanson, Charles C. Valentine, Jesse J. Salk, Emily Loter, Robert Zeillinger, Kaitlyn Loubet-Senear, Lindsey N. Williams, Adriaan Vanderstichele, Lawrence A. Loeb, Kathryn T. Baker
High accuracy next-generation DNA sequencing promises a paradigm shift in early cancer detection by enabling the identification of mutant cancer molecules in minimally-invasive body fluid samples. We demonstrate 80% sensitivity for ovarian cancer det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ba92f0f22af85b0a54bfd054a80140
https://doi.org/10.1101/457291
https://doi.org/10.1101/457291