Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Lindsey M Brier"'
Autor:
Patrick W Wright, Lindsey M Brier, Adam Q Bauer, Grant A Baxter, Andrew W Kraft, Matthew D Reisman, Annie R Bice, Abraham Z Snyder, Jin-Moo Lee, Joseph P Culver
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185759 (2017)
The interplay between hemodynamic-based markers of cortical activity (e.g. fMRI and optical intrinsic signal imaging), which are an indirect and relatively slow report of neural activity, and underlying synaptic electrical and metabolic activity thro
Externí odkaz:
https://doaj.org/article/dbb20ca61ad74ab69ed44a3c8e6f3a27
Autor:
Rachel M Rahn, Allen Yen, Siyu Chen, Seana H Gaines, Annie R Bice, Lindsey M Brier, Raylynn G Swift, LeiLani Lee, Susan E Maloney, Joseph P Culver, Joseph D Dougherty
Publikováno v:
Cerebral Cortex.
As a regressive neurodevelopmental disorder with a well-established genetic cause, Rett syndrome and its Mecp2 loss-of-function mouse model provide an excellent opportunity to define potentially translatable functional signatures of disease progressi
Autor:
Lindsey M. Brier, Joseph P. Culver
Publikováno v:
Neurophotonics. 10
Autor:
Julian V Clarke, Lindsey M Brier, Rachel M Rahn, Deepti Diwan, Jane Y Yuan, Annie R Bice, Shin-ichiro Imai, Ananth K Vellimana, Joseph P Culver, Gregory J Zipfel
Publikováno v:
J Cereb Blood Flow Metab
Functional connectivity (FC) is a sensitive metric that provides a readout of whole cortex coordinate neural activity in a mouse model. We examine the impact of experimental SAH modeled through endovascular perforation, and the effectiveness of subse
Autor:
Joseph P. Culver, Joseph D. Dougherty, Lindsey M. Brier, Annie R. Bice, Rachel M. Rahn, Matthew D. Reisman
Publikováno v:
Cereb Cortex
Cross-sectional studies have established a variety of structural, synaptic, and cell physiological changes corresponding to critical periods in cortical development. However, the emergence of functional connectivity (FC) in development has not been f
Autor:
Rachel M. Rahn, Allen Yen, Siyu Chen, Seana H. Gaines, Annie R. Bice, Lindsey M. Brier, Raylynn G. Swift, LeiLani Lee, Susan E. Maloney, Joseph P. Culver, Joseph D. Dougherty
As a regressive neurodevelopmental disorder with a well-established genetic cause, Rett Syndrome and its Mecp2 loss-of-function mouse model provide an excellent opportunity to define potentially translatable functional signatures of disease progressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d5a3593e74df2799961c2afff109460
https://doi.org/10.1101/2021.10.28.466323
https://doi.org/10.1101/2021.10.28.466323
Autor:
Joseph P. Culver, Lindsey M. Brier
Wide-field optical imaging (WOI) produces concurrent hemodynamic and cell-specific calcium recordings across the entire cerebral cortex. There have been multiple studies using WOI to image mouse models with various environmental or genetic manipulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3573ea44adc8893ab9b88890d4b0b2
https://doi.org/10.1101/2021.04.07.438885
https://doi.org/10.1101/2021.04.07.438885
Autor:
Eric C. Landsness, Seana H Gaines, Annie R. Bice, Lindsey M. Brier, Joseph P. Culver, Xiaohui Zhang, Mark A. Anastasio, Jin-Moo Lee
Publikováno v:
Cereb Cortex
Temporal correlation analysis of spontaneous brain activity (e.g., Pearson “functional connectivity,” FC) has provided insights into the functional organization of the human brain. However, bivariate analysis techniques such as this are often sus
Autor:
Seana H Gaines, Jon R. Bumstead, Lindsey M. Brier, Hunter Banks, Annie R. Bice, Joseph P. Culver
Publikováno v:
Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics.
By paying careful attention to optical and mechanical design, a two-photon microscope (TPM) can image a large field of view (FOV) with high spatial and temporal resolution. Successfully applying such a TPM for functional neuroimaging requires careful
Autor:
Jan R. Crowley, Azad Bonni, Joseph P. Culver, Thomas Papouin, Nicholas Rensing, Lindsey M. Brier, Annie R. Bice, Marcia C. Haigis, Joseph E. Ippolito, Anna Oldenborg, Krikor Dikranian, Michael Wong, Alison E. Ringel, Guoyan Zhao, Sarah E. Smith, Jonathan R. Bumstead, Xiaoying Chen, Haewon Shin
Publikováno v:
Communications Biology
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Familial hemiplegic migraine is an episodic neurological disorder characterized by transient sensory and motor symptoms and signs. Mutations of the ion pump α2-Na/K ATPase cause familial hemiplegic migraine, but the mechanisms by which α2-Na/K ATPa