Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Lindsey K Stolze"'
Autor:
Maria L Adelus, Jiacheng Ding, Binh T Tran, Austin C Conklin, Anna K Golebiewski, Lindsey K Stolze, Michael B Whalen, Darren A Cusanovich, Casey E Romanoski
Publikováno v:
eLife, Vol 12 (2024)
Heterogeneity in endothelial cell (EC) sub-phenotypes is becoming increasingly appreciated in atherosclerosis progression. Still, studies quantifying EC heterogeneity across whole transcriptomes and epigenomes in both in vitro and in vivo models are
Externí odkaz:
https://doaj.org/article/c8175c955d6e480189b526a1dbd02b29
Autor:
Zeyang Shen, Rick Z Li, Thomas A Prohaska, Marten A Hoeksema, Nathan J Spann, Jenhan Tao, Gregory J Fonseca, Thomas Le, Lindsey K Stolze, Mashito Sakai, Casey E Romanoski, Christopher K Glass
Publikováno v:
eLife, Vol 11 (2022)
Regulation of gene expression requires the combinatorial binding of sequence-specific transcription factors (TFs) at promoters and enhancers. Prior studies showed that alterations in the spacing between TF binding sites can influence promoter and enh
Externí odkaz:
https://doaj.org/article/98d44d7ff9f64f50bf3ced74f1b45425
Autor:
Nicholas T Hogan, Michael B Whalen, Lindsey K Stolze, Nizar K Hadeli, Michael T Lam, James R Springstead, Christopher K Glass, Casey E Romanoski
Publikováno v:
eLife, Vol 6 (2017)
Endothelial cells (ECs) are critical determinants of vascular homeostasis and inflammation, but transcriptional mechanisms specifying their identities and functional states remain poorly understood. Here, we report a genome-wide assessment of regulat
Externí odkaz:
https://doaj.org/article/25b57f160a724bd897fd2d963a30394d
Autor:
Adam W. Watson, Adam D. Grant, Sara S. Parker, Samantha Hill, Michael B. Whalen, Jayati Chakrabarti, Michael W. Harman, Mackenzie R. Roman, Brittany L. Forte, Cody C. Gowan, Raúl Castro-Portuguez, Lindsey K. Stolze, Christian Franck, Darren A. Cusanovich, Yana Zavros, Megha Padi, Casey E. Romanoski, Ghassan Mouneimne
Publikováno v:
Cell Reports, Vol 35, Iss 13, Pp 109293- (2021)
Summary: While the immediate and transitory response of breast cancer cells to pathological stiffness in their native microenvironment has been well explored, it remains unclear how stiffness-induced phenotypes are maintained over time after cancer c
Externí odkaz:
https://doaj.org/article/9120a5dd6d85476791e874d67897611c
Autor:
Maria L. Adelus, Jiacheng Ding, Binh T. Tran, Austin C. Conklin, Anna K. Golebiewski, Lindsey K. Stolze, Michael B. Whalen, Darren A. Cusanovich, Casey E. Romanoski
ObjectiveEndothelial cells (ECs) regulate atherogenesis with Endothelial-to-Mesenchymal (EndMT) transition correlating with disease. Single cell (sc) effects of EndMT perturbationsin vitro,with quantitative comparison to signatures of human lesionsin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc57dd8371e8b9d190189ce6291c8c2e
https://doi.org/10.1101/2023.04.03.535495
https://doi.org/10.1101/2023.04.03.535495
Autor:
Ilakya Selvarajan, Jin Li, Petri Pölönen, Tiit Örd, Kadri Õunap, Aarthi Ravindran, Kiira Mäklin, Anu Toropainen, Lindsey K. Stolze, Stephen White, Casey E. Romanoski, Merja Heinäniemi, Yun Fang, Minna Kaikkonen-Määttä
Coronary artery disease (CAD) is one of the major causes of mortality worldwide. Recent genome-wide association studies have started to unravel the genetic architecture of the disease. Such efforts have identified Calcitonin receptor-like (CALCRL), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e151be10fc3938e1c28e80d8eaa4bb9
https://doi.org/10.1101/2023.02.08.527795
https://doi.org/10.1101/2023.02.08.527795
Autor:
Zeyang Shen, Rick Z Li, Thomas A Prohaska, Marten A Hoeksema, Nathan J Spann, Jenhan Tao, Gregory J Fonseca, Thomas Le, Lindsey K Stolze, Mashito Sakai, Casey E Romanoski, Christopher K Glass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4175c3566ce7d3c1ecff2e2adfb25f9d
https://doi.org/10.7554/elife.70878.sa2
https://doi.org/10.7554/elife.70878.sa2
Autor:
Lindsey K Stolze, Anu Toropainen, Tiit Ord, Michael B Whalen, Minna Kaikkonen, Casey E Romanoski
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Genome-wide association studies have linked thousands of genetic variants with complex diseases and traits. However, most genetic variants identified reside in non-coding regions of the genome, including variants associated with a myriad of vascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71900c6d1becf2b88a7c5d67fb7fe2bb
https://doi.org/10.1161/atvb.41.suppl_1.104
https://doi.org/10.1161/atvb.41.suppl_1.104
Autor:
Paula Marta Torrell, Verena M. Link, Casey E. Romanoski, Michael B. Whalen, Anu Toropainen, Tiit Örd, Lindsey K. Stolze, Minna U. Kaikkonen
Functional consequences of genetic variation in the non-coding human genome are difficult to ascertain despite demonstrated associations to common, complex disease traits. To elucidate properties of functional non-coding SNPs with effects in human en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92ec812394d36d984ff595f988bb9372
https://doi.org/10.1101/2021.08.03.454513
https://doi.org/10.1101/2021.08.03.454513
Autor:
Anu Toropainen, Lindsey K. Stolze, Tiit Örd, Michael B. Whalen, Paula Martí Torrell, Verena M. Link, Minna U. Kaikkonen, Casey E. Romanoski
Publikováno v:
Genome research. 32(3)
Functional consequences of genetic variation in the noncoding human genome are difficult to ascertain despite demonstrated associations to common, complex disease traits. To elucidate properties of functional noncoding SNPs with effects in human endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2824748e46b0a21979dba99ca9cc82d0
https://pubmed.ncbi.nlm.nih.gov/35193936
https://pubmed.ncbi.nlm.nih.gov/35193936