Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lindsey J. Panton"'
Autor:
Russell J. Howard, Stephen B. Aley, James A. Sherwood, Masamichi Aikawa, F W Klotz, Allan Saul, Jeffrey A. Lyon, Shigehiko Uni, Kevin Marsh, Lindsey J. Panton
Publikováno v:
The Journal of Cell Biology
The profound changes in the morphology, antigenicity, and functional properties of the host erythrocyte membrane induced by intraerythrocytic parasites of the human malaria Plasmodium falciparum are poorly understood at the molecular level. We have u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85da858846492b19ab1e3595b16e189c
https://ora.ox.ac.uk/objects/uuid:2af4c600-70b4-46b7-8a38-f8f5e89a458a
https://ora.ox.ac.uk/objects/uuid:2af4c600-70b4-46b7-8a38-f8f5e89a458a
Publikováno v:
Molecular and Biochemical Parasitology. 51:313-320
We report a genetic linkage map of the Plasmodium falciparum genome, using the inheritance patterns of nearly 90 RFLP markers in a genetic cross. Markers were assigned to polymorphic loci on all 14 nuclear chromosomes. Genetic recombination between p
Publikováno v:
The Journal of Protozoology. 38:224-228
We tested if genetic exchange was observable between two strains of Leishmania major (Trypanosomatidae) during mixed infection of the sand fly Phlebotomus papatasi. Previous studies suggested that genetic exchange may occur in natural populations of
The resurgence of malaria in recent decades has been accompanied by the worldwide spread of resistance to chloroquine, a drug once uncontested as the first-line antimalarial agent because of its efficacy and low toxicity. Chloroquine-resistant strain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e933eb5d73ede5382829534fbe67a3
https://europepmc.org/articles/PMC51451/
https://europepmc.org/articles/PMC51451/
Publikováno v:
Parasitology. 89:27-34
SummaryThe inheritance of an antigen designated Py-1 in the rodent malaria parasitePlasmodium yoeliihas been investigated. A cross was made between 2 lines differing in the electrophoretic mobility and quantity of Py-1 detected by crossed immunoelect
Autor:
McPhie P, Lindsey J. Panton, Thomas E. Wellems, Maloy Wl, Diane Wallace Taylor, Russell J. Howard
Publikováno v:
Molecular and Biochemical Parasitology. 35:149-160
The human malarial parasite Plasmodium falciparum secretes a histidine-rich protein (HRP-II) from infected erythrocytes. HRP-II has a very high content of histidine (H) (34%), alanine (A) (37%) and aspartic acid (D) (10%) and many contiguous repeats
Publikováno v:
Parasitology. 89:17-26
SummaryAntigens of three lines of the rodent malaria parasitePlasmodium yoeliihave been studied using crossed immunoelectrophoresis.P. y. yoeliiline A1is a mild line which is restricted to reticulocytes.P. y. yoeliiline YM andP. y. nigeriensisline D1
Autor:
M Aikawa, Lindsey J. Panton, A Escajadillo, A T Lee, R N Rossan, K L Kirk, R J Howard, L A Cohen, V M Labroo, Y Matsumoto
The effects of four halogenated analogs of histidine on in vitro growth of Plasmodium falciparum malaria parasites were monitored by measurement of the incorporation of 3H-labeled amino acids into parasite proteins and by light and electron microscop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3a2c29590d8a6853c7876dffe516a4
https://europepmc.org/articles/PMC175947/
https://europepmc.org/articles/PMC175947/
Autor:
Russell J. Howard, J Ellen J. Winchell, Lindsey J. Panton, R. J. M. Wilson, Irene T. Ling, Kevin Marsh
Publikováno v:
Parasite immunology. 8(1)
Summary Ring-stage asexual parasites of P. falciparum were collected from six Gambian children and the S-antigens radiolabeled by 3H-glycine uptake during in vitro culture up to rupture of infected cells and merozoite release. Ouchterlony double diff
Autor:
Russell J. Howard, Shigehiko Uni, Mark E. Stearns, George B. Chapman, Lindsey J. Panton, Diane Wallace Taylor, Stephen B. Aley, Marcela Parra, Joan Rener, Masamichi Aikawa
Publikováno v:
Molecular and biochemical parasitology. 25(2)
Plasmodium falciparum parasites that induce knobs in the host erythrocyte membrane (K+ phenotype) synthesize a 90 kDa histidine-rich protein (PfHRP-1), whereas knobless variants do not. A monoclonal antibody (mAb 89) to PfHRP-1, in combination with c