Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lindsey H. Remark"'
Autor:
Lindsey H. Remark, Kevin Leclerc, Malissa Ramsukh, Ziyan Lin, Sooyeon Lee, Backialakshmi Dharmalingam, Lauren Gillinov, Vasudev V. Nayak, Paulo El Parente, Margaux Sambon, Pablo J. Atria, Mohamed A. E. Ali, Lukasz Witek, Alesha B. Castillo, Christopher Y, Park, Ralf H. Adams, Aristotelis Tsirigos, Sophie M. Morgani, Philipp Leucht
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Skeletal stem and progenitor cells (SSPCs) perform bone maintenance and repair. With age, they produce fewer osteoblasts and more adipocytes leading to a loss of skeletal integrity. The molecular mechanisms that underlie this detrimental tra
Externí odkaz:
https://doaj.org/article/0d64cab140164afb8b8aaf26ab3db645
Autor:
Kevin Leclerc, Lindsey H. Remark, Malissa Ramsukh, Anne Marie Josephson, Laura Palma, Paulo E. L. Parente, Margaux Sambon, Sooyeon Lee, Emma Muiños Lopez, Sophie M. Morgani, Philipp Leucht
Publikováno v:
Development. 150
Periosteal stem and progenitor cells (PSPCs) are major contributors to bone maintenance and repair. Deciphering the molecular mechanisms that regulate their function is crucial for the successful generation and application of future therapeutics. Her
Publikováno v:
Aging (Albany NY)
Aging tissues undergo a progressive decline in regenerative potential. This decline in regenerative responsiveness has been attributed to changes in tissue-specific stem cells and their niches. In bone, aged skeletal stem/progenitor cell dysfunction
Autor:
Kevin Leclerc, Lindsey H. Remark, Malissa Ramsukh, Anne Marie Josephson, Sophie M. Morgani, Laura Palma, Paulo EL Parente, Sooyeon Lee, Emma Muiños Lopez, Philipp Leucht
Periosteal stem and progenitor cells are pivotal to the growth and lifelong turnover of bone and underpin its capacity to regenerate. Adjusting the potency of this cell population will therefore be critical to the successful generation and applicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bd359cef106386fa214fe375b1e3048
https://doi.org/10.1101/2022.05.15.492027
https://doi.org/10.1101/2022.05.15.492027
Publikováno v:
Journal of Orthopaedic Science.
Multiple techniques have been developed for the repair of acute quadriceps and patellar tendon ruptures with the goal of optimizing clinical outcomes while minimizing complications and costs. The purpose of this study was to evaluate the biomechanica
Autor:
Emma Muiños Lopez, Kevin Leclerc, Malissa Ramsukh, Paulo EL Parente, Karan Patel, Carlos J. Aranda, Anna M. Josephson, Lindsey H. Remark, David J. Kirby, Daniel B. Buchalter, Tarik Hadi, Sophie M. Morgani, Bhama Ramkhelawon, Philipp Leucht
Publikováno v:
Bone
Tissue injury leads to the well-orchestrated mobilization of systemic and local innate and adaptive immune cells. During aging, immune cell recruitment is dysregulated, resulting in an aberrant inflammatory response that is detrimental for successful
Autor:
Ruchi Tejwani, Danielle H. Markus, Philipp Leucht, Kevin Leclerc, Madeleine Z. Wong, Lindsey H. Remark, Hannah P. Litwa, Vivian Bradaschia-Correa, Sooyeon Lee, Daniel B Buchalter, Rivka C. Ihejirika, Nury L. Yim, Anne M Josephson
Publikováno v:
J Bone Miner Res
Selective serotonin reuptake inhibitors (SSRIs) are one of the most commonly prescribed antidepressants worldwide and recent data show significant impairment of fracture healing after treatment with the SSRI fluoxetine in mice. Here, we provide evide