Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lindsey F. Nugent"'
Autor:
Osato Ogbeifun, Samuel J. H. Hinshaw, Lindsey F. Nugent, Ignacio R. Rodriguez, Igal Gery, Siqi Chen, Wambui S. Wandu, Arvydas Maminishkis, Guangpu Shi
Publikováno v:
Investigative Ophthalmology & Visual Science. 56:1658-1664
PURPOSE The inflammatory process plays a major role in the pathogenesis of AMD, and recent data indicate the involvement of inflammasomes. Inflammasomes are intracellular structures that trigger inflammation by producing mature interleukin-(IL)-1β a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f073a9a764e02e06f35860f1b7c89ab9
https://doi.org/10.1167/iovs.14-14557
https://doi.org/10.1167/iovs.14-14557
Autor:
Igal Gery, Lindsey F. Nugent, Cuiyan Tan, Dennis M. Klinman, Barbara P. Vistica, Eric F. Wawrousek, Guangpu Shi
Publikováno v:
The Journal of Immunology. 191:415-423
The interaction between TLRs and their cognate ligands triggers both the innate and adaptive immune systems, and thus can play a pivotal role in the defense against pathogen invasion. This work investigates the differentiation of naive CD4 cells into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5138d3479c54ab8fd1dcddfb883676
https://doi.org/10.4049/jimmunol.1201732
https://doi.org/10.4049/jimmunol.1201732
Autor:
Samuel J. H. Hinshaw, Guangpu Shi, Barbara P. Vistica, Lindsey F. Nugent, Osato Ogbeifun, Igal Gery
Publikováno v:
Investigative ophthalmologyvisual science. 54(12)
Purpose Ligands for aryl hydrocarbon receptor (AHR), such as dioxins, are highly toxic. One such ligand, TCDD, was found to exert potent immunosuppressive capacities in mice developing pathogenic autoimmune processes, including EAU, but its toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6c05316a907a4a3aee91dd41f08a4d
https://pubmed.ncbi.nlm.nih.gov/24150760
https://pubmed.ncbi.nlm.nih.gov/24150760
Autor:
Kimberly Boelte, Lindsey F. Nugent, Daniel W. McVicar, Toshiyuki Takai, V. Montalvo, Igal Gery, Laura Quigley, Barbara P. Vistica
Publikováno v:
Immunology. 140(4)
DNAX-activation protein 12 (DAP12), a transmembrane adapter, plays a major role in transducing activation signals in natural killer cells and various myeloid cells. Quantitative RT-PCR detected in normal mouse eyes considerable levels of DAP12 and mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c321e866d88591f44af28a64476901
https://pubmed.ncbi.nlm.nih.gov/23906311
https://pubmed.ncbi.nlm.nih.gov/23906311