Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lindsey E. Fox"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Type I interferons (IFNs) are critical effector cytokines of the immune system and were originally known for their important role in protecting against viral infections; however, they have more recently been shown to play protective or detrimental ro
Externí odkaz:
https://doaj.org/article/b11ec326915a46b48018170788316ff2
Autor:
Lindsey E. Fox, Deborah J. Lenschow
Publikováno v:
Cell hostmicrobe. 30(1)
Effector-triggered immunity involves "guarded" host processes that, when perturbed by pathogen factors, prompt a secondary response. A recent study published in Nature by Gaidt et al. demonstrates that MORC3 serves as both the guard and the guarded a
Autor:
Marissa C. Locke, Kristen Monte, Lindsey E. Fox, Alissa R. Young, Bria F. Dunlap, Deborah J. Lenschow
Publikováno v:
J Virol
Chikungunya virus (CHIKV) is an arthritogenic alphavirus that causes both debilitating acute and chronic disease. Previous work has shown that type I interferons (IFNs) play a critical role in limiting CHIKV pathogenesis and that interferon alpha (IF
Autor:
Kristen Monte, L. David Sibley, Devesha H. Kulkarni, Jiani N. Chai, Jisun Jung, Georgia Wilke, Alec Wehmeier, Chyi-Song Hsieh, Bernd H. Zinselmeyer, Aidan T. Miller, Jaeu Yi, Vivek Durai, Rafael S. Czepielewski, Shannon Young, Suellen Greco, Kenneth M. Murphy, Lindsey E. Fox, Lisa J. Funkhouser-Jones, Rodney D. Newberry, Emilie V. Russler-Germain
Publikováno v:
Immunity. 54:2547-2564.e7
Summary Cryptosporidium can cause severe diarrhea and morbidity, but many infections are asymptomatic. Here, we studied the immune response to a commensal strain of Cryptosporidium tyzzeri (Ct-STL) serendipitously discovered when conventional type 1
Autor:
Bradley E Hiller, Yongjun Yin, Yi-Chieh Perng, Ítalo de Araujo Castro, Lindsey E Fox, Marissa C Locke, Kristen J Monte, Carolina B López, David M Ornitz, Deborah J Lenschow
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010228 (2022)
Influenza A virus (IAV) preferentially infects conducting airway and alveolar epithelial cells in the lung. The outcome of these infections is impacted by the host response, including the production of various cytokines, chemokines, and growth factor
Externí odkaz:
https://doaj.org/article/a0c0e8f27fd44ecfa41112866636508b