Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lindsey D Bogachus"'
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 103:1522-1529
CONTEXT: Total pancreatectomy and intrahepatic islet autotransplantation (TP/IAT) is performed to alleviate severe abdominal pain, avoid narcotic use, maintain islet function, and avoid diabetes in patients with chronic pancreatitis. However, many TP
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 102:3288-3295
Context Total pancreatectomy followed by intrahepatic islet autotransplantation (TP/IAT) is performed to alleviate severe, unrelenting abdominal pain caused by chronic pancreatitis, to improve quality of life, and to prevent diabetes. Objective To de
Autor:
Vincenzo Cirulli, Michele Black, Elizabeth Oseid, Stephanie Hahn, Lindsey D. Bogachus, Tsehay Abebe, Jana Mahadevan, Fumihiko Urano, R. Paul Robertson
Publikováno v:
JCI Insight. 2
Many theories have been advanced to better understand why β cell function and structure relentlessly deteriorate during the course of type 2 diabetes (T2D). These theories include inflammation, apoptosis, replication, neogenesis, autophagy, differen
Autor:
Lindsey D. Bogachus, Timothy L. Pruett, Melena D. Bellin, Michael R. Rickels, David E.R. Sutherland, R. Paul Robertson, Susan D. Parazzoli, Appakalai N. Balamurugan, Gregory J. Beilman, Christian Schuetz, Mary-Elizabeth Patti, Elizabeth Oseid, Ty B. Dunn
Publikováno v:
Diabetes
We used intravenous arginine with measurements of insulin, C-peptide, and glucagon to examine β-cell and α-cell survival and function in a group of 10 chronic pancreatitis recipients 1–8 years after total pancreatectomy and autoislet transplantat
Autor:
Bernhard J. Hering, Timothy L. Pruett, Melena D. Bellin, R. P. Robertson, Mary-Elizabeth Patti, Christian Schuetz, Elizabeth Oseid, Ty B. Dunn, Gregory J. Beilman, D. E. R. Sutherland, Appakalai N. Balamurugan, Susan D. Parazzoli, Lindsey D Bogachus
Publikováno v:
American Journal of Transplantation. 14:1880-1886
Defective glucagon secretion during hypoglycemia after islet transplantation has been reported in animals and humans with type 1 diabetes. To ascertain whether this is true of islets from nondiabetic humans, subjects with autoislet transplantation in
Autor:
Lorraine P. Turcotte, Anders Thorell, Christina Koutsari, David A. Bernlohr, Sandra J. Taler, Manpreet S. Mundi, Jonas Nygren, Asem H. Ali, Julie K. Heimbach, Lindsey D. Bogachus, Mark D. Stegall, Michael D. Jensen
Publikováno v:
Diabetes
OBJECTIVE Because direct adipose tissue free fatty acid (FFA) storage may contribute to body fat distribution, we measured FFA (palmitate) storage rates and fatty acid (FA) storage enzymes/proteins in omental and abdominal subcutaneous fat. RESEARCH
Publikováno v:
American Journal of Physiology-Cell Physiology. 299:C1549-C1561
Metformin is known to improve insulin sensitivity in part via a rise in AMP-activated protein kinase (AMPK) activity and alterations in muscle metabolism. However, a full understanding of how metformin alters AMPK-α1vs. AMPK-α2activation remains un
Autor:
Janet L. Vierck, Michael V. Dodson, Carrie P. Nevins, Nicole S. Velotta, Federico Castro-Muñozledo, Lindsey D. Bogachus
Publikováno v:
Cytotechnology. 49:71-75
A method is described for assembling an evaporation manifold from a cell culture flask, which allows for efficient nitrogen evaporation of hexane from 24- and 96-well plates. The precursor parts are readily available in most research laboratories. Th
Publikováno v:
Journal of Antivirals & Antiretrovirals.
C-Jun-N-terminal kinase (JNK1/2) pro-inflammatory signaling has been shown to play a role in highly active antiretroviral therapy (HAART)-induced insulin resistance in skeletal muscle cells. To determine the effectiveness of metformin and resveratrol
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 111(1)
AMP-activated protein kinase (AMPK) is a fuel sensor in skeletal muscle with multiple downstream signaling targets that may be triggered by increases in intracellular Ca2+concentration ([Ca2+]). The purpose of this study was to determine whether incr