Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Lindsey B, Crawford"'
Autor:
Samuel Medica, Lindsey B Crawford, Michael Denton, Chan-Ki Min, Taylor A Jones, Timothy Alexander, Christopher J Parkins, Nicole L Diggins, Gabriel J Streblow, Adam T Mayo, Craig N Kreklywich, Patricia Smith, Sophia Jeng, Shannon McWeeney, Meaghan H Hancock, Andrew Yurochko, Michael S Cohen, Patrizia Caposio, Daniel N Streblow
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011682 (2023)
Human cytomegalovirus (HCMV) encodes multiple putative G protein-coupled receptors (GPCRs). US28 functions as a viral chemokine receptor and is expressed during both latent and lytic phases of virus infection. US28 actively promotes cellular migratio
Externí odkaz:
https://doaj.org/article/c4deb3fdeb3d4b18942e4ecdab4602f4
Autor:
Lindsey B. Crawford
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
The human betaherpesviruses including human cytomegalovirus (HCMV), human herpesvirus (HHV)-6a and HHV-6b, and HHV-7 infect and establish latency in CD34+ hematopoietic stem and progenitor cells (HPCs). The diverse repertoire of HPCs in humans and th
Externí odkaz:
https://doaj.org/article/f5a4632044254c7b832806a2f8a00c1d
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Human cytomegalovirus (HCMV) is a highly prevalent beta-herpesvirus and a significant cause of morbidity and mortality following hematopoietic and solid organ transplant, as well as the leading viral cause of congenital abnormalities. A key
Externí odkaz:
https://doaj.org/article/d1611c7c034140f68ba91dbe8d45937d
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Each herpesvirus family establishes latency in a unique cell type. Since herpesviruses genomes are maintained as episomes, the viruses need to devise mechanisms to retain the latent genome during cell division.
Externí odkaz:
https://doaj.org/article/7beab12f4ad247e89b494036072c8109
Autor:
Meaghan H. Hancock, Lindsey B. Crawford, Wilma Perez, Hillary M. Struthers, Jennifer Mitchell, Patrizia Caposio
Publikováno v:
mSphere, Vol 6, Iss 1 (2021)
Human cytomegalovirus (HCMV) causes serious disease in immunocompromised individuals and is a significant problem during transplantation. The virus can establish a latent infection in CD34 +
Externí odkaz:
https://doaj.org/article/ec079e6dd1f34673afbd2b6fe21c35f1
Autor:
Lindsey B. Crawford, Rebecca Tempel, Daniel N. Streblow, Craig Kreklywich, Patricia Smith, Louis J. Picker, Jay A. Nelson, Patrizia Caposio
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract The strict species specificity of Human Cytomegalovirus (HCMV) has impeded our understanding of antiviral adaptive immune responses in the context of a human immune system. We have previously shown that HCMV infection of human hematopoietic
Externí odkaz:
https://doaj.org/article/63f137c8af204eeab7c5949faeb8e663
Autor:
Iliyana Mikell, Lindsey B Crawford, Meaghan H Hancock, Jennifer Mitchell, Jason Buehler, Felicia Goodrum, Jay A Nelson
Publikováno v:
PLoS Pathogens, Vol 15, Iss 11, p e1007854 (2019)
Reactivation of latent Human Cytomegalovirus (HCMV) in CD34+ hematopoietic progenitor cells (HPCs) is closely linked to hematopoiesis. Viral latency requires maintenance of the progenitor cell quiescence, while reactivation initiates following mobili
Externí odkaz:
https://doaj.org/article/c5b0156f73024df2935fdfc37b1ec146
Autor:
Lindsey B. Crawford, Patrizia Caposio, Craig Kreklywich, Andrew H. Pham, Meaghan H. Hancock, Taylor A. Jones, Patricia P. Smith, Andrew D. Yurochko, Jay A. Nelson, Daniel N. Streblow
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Human cytomegalovirus (HCMV) infection of CD34+ hematopoietic progenitor cells (CD34+ HPCs) provides a critical reservoir of virus in stem cell transplant patients, and viral reactivation remains a significant cause of morbidity and mortalit
Externí odkaz:
https://doaj.org/article/2213cd7c92b0456f946b96b2a577e848
Autor:
Lindsey B, Crawford
Publikováno v:
Current Protocols. 2
Pluripotent human embryonic stem cell (hESC) lines are a valuable in vitro tool to differentiate specific cell lineages, including cells from all three germ layers, i.e., neuronal cells, myocytes, and hematopoietic cells, including progenitors (descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4ab162afdab4c579fd15925490408a
https://doi.org/10.1002/cpz1.622
https://doi.org/10.1002/cpz1.622
Autor:
Lindsey B. Crawford, Rebecca Tempel, Daniel N. Streblow, Andrew D. Yurochko, Felicia D. Goodrum, Jay A. Nelson, Patrizia Caposio
Publikováno v:
Microorganisms, Vol 8, Iss 4, p 525 (2020)
Human cytomegalovirus (HCMV) infection is a serious complication in hematopoietic stem cell transplant (HSCT) recipients due to virus-induced myelosuppression and impairment of stem cell engraftment. Despite the clear clinical link between myelosuppr
Externí odkaz:
https://doaj.org/article/fd04cf77fd6d44d2a57c0f8ec7654d01