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pro vyhledávání: '"Lindsey Anne Dudley"'
Autor:
Lindsey Anne Dudley, Stephen C. J. Parker, Sally A. Camper, Michael T. Peel, Alexandre Z. Daly, Stephen A. Liebhaber
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-21 (2021)
BMC Biology
BMC Biology
BackgroundThe pituitary gland is a neuroendocrine organ containing diverse cell types specialized in secreting hormones that regulate physiology. Pituitary thyrotropes produce thyroid-stimulating hormone (TSH), a critical factor for growth and mainte
Autor:
Lindsey Anne Dudley, Michael T. Peel, Stephen C. J. Parker, Sally A. Camper, Alexandre Z. Daly, Stephen A. Liebhaber
Pituitary thyrotropes are specialized cells that produce thyroid stimulating hormone (TSH), a critical factor for growth and maintenance of metabolism. The transcription factors POU1F1 and GATA2 have been implicated in thyrotrope fate and transcripti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d9cbd358c76dbdf8421f2151876aae6
https://doi.org/10.1101/2020.08.05.238253
https://doi.org/10.1101/2020.08.05.238253
Autor:
Lindsey Anne Dudley, Alexandre Zacharie Daley, Sally A. Camper, Amanda H. Mortensen, Michelle L. Brinkmeier, Leonard Y.M. Cheung, Rachna Sridhar
Publikováno v:
Journal of the Endocrine Society
Many transcription factors have been identified that are important for specification and differentiation of the hormone-producing cells of the pituitary gland. For example, POU1F1 is essential for differentiation of thyrotropes, somatotropes, and lac
Publikováno v:
Journal of the Endocrine Society
Pituitary and hypothalamic cell lines have been developed by targeted oncogenesis. This involved using cell-specific transcriptional regulatory sequences to drive expression of large and small SV40 T-antigens in transgenic mice. Invariably, tumors de