Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lindsei K. Sarna"'
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 309:R1215-R1225
AMPK is an endogenous energy sensor that regulates lipid and carbohydrate metabolism. Nonalcoholic fatty liver disease (NAFLD) is regarded as a hepatic manifestation of metabolic syndrome with impaired lipid and glucose metabolism and increased oxida
Activation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase during high fat diet feeding
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1832(10):1560-1568
The liver plays a central role in regulating cholesterol homeostasis. High fat diets have been shown to induce obesity and hyperlipidemia. Despite considerable advances in our understanding of cholesterol metabolism, the regulation of liver cholester
Autor:
Hooman Derakhshani, Yue Shang, Ehsan Khafipour, Connie W.H. Woo, Yaw L. Siow, Karmin O, Lindsei K. Sarna
Publikováno v:
Lipids. 52(6)
The gut microbiota is proposed as a “metabolic organ” involved in energy utilization and is associated with obesity. Dietary intervention is one of the approaches for obesity management. Changes in dietary components have significant impacts on h
Publikováno v:
Applied Physiology, Nutrition, and Metabolism. 37:1164-1170
Oxidative stress plays an important role in the development of atherosclerosis. Excess visceral adipose tissue (VAT) and increased carotid intima-media thickness (IMT) are risk factors for coronary artery disease. We tested the hypothesis that VAT an
Publikováno v:
Food Research International. 44:2409-2417
Oxidative stress is a cellular event that occurs at the molecular level and arises when the balance of intrinsic antioxidants and reactive molecular species tips towards the latter. Although oxidative stress has been implicated in the pathophysiology
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 88:369-378
Oxidative stress and amplified redox signaling contribute to the pathogenesis of many human diseases including atherosclerosis. The superoxide-generating phagocytic NADPH oxidase is a key source of oxidative stress in the developing atheroma. The aim
Publikováno v:
Lipids. 51(5)
The Mediterranean diet is known for its cardioprotective effects. Recently, its protective qualities have also been reported in patients with non-alcoholic fatty liver disease (NAFLD). Oxidative stress is one of the important factors responsible for
Autor:
Yaw L. Siow, Lindsei K. Sarna
Publikováno v:
Canadian journal of physiology and pharmacology. 93(1)
Non-alcoholic fatty liver disease (NAFLD) is a broad spectrum liver disorder diagnosed in patients without a history of alcohol abuse. NAFLD is growing at alarming rates worldwide. Its pathogenesis is complex and incompletely understood. The cystathi
Publikováno v:
The FASEB Journal. 28
High fat diets (HFD) are obesogenic and predispose to metabolic syndromes. Non-alcoholic fatty liver disease (NAFLD), a hepatic manifestation of the metabolic syndrome, is characterized by hepatic steatosis with progression to steatohepatitis in adva
Publikováno v:
The FASEB Journal. 25