Oxygen Consumption Rates Between Skeletal Muscle Cells Derived from Young and Old Human Donors Elucidate Mitochondrial Dysfunction

Autor: Park, Lindsay (Na Yeon), Arevalo, José, Brooks, George, Lishko, Polina

Publikováno v: Berkeley Scientific Journal, vol 27, iss 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::3aa915f067e0c1e2905b0e32badd79b5
https://escholarship.org/uc/item/1fj2t7js

Building a Culture of Champions: The Importance of Leadership in Resuscitation

Autor: Amanda O’Halloran, Lindsay Nadkarni Shepard, Vinay M. Nadkarni

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 5 (2021)

Externí odkaz: https://doaj.org/article/15f72d3265c14a23b00284e932fac9d1

Using the Five Domains Model to Assess the Adverse Impacts of Husbandry, Veterinary, and Equitation Interventions on Horse Welfare

Autor: Paul McGreevy, Jeannine Berger, Nic de Brauwere, Orla Doherty, Anna Harrison, Julie Fiedler, Claudia Jones, Sue McDonnell, Andrew McLean, Lindsay Nakonechny, Christine Nicol, Liane Preshaw, Peter Thomson, Vicky Tzioumis, John Webster, Sarah Wolfensohn, James Yeates, Bidda Jones

Publikováno v: Animals, Vol 8, Iss 3, p 41 (2018)

The aim of this study was to conduct a series of paper-based exercises in order to assess the negative (adverse) welfare impacts, if any, of common interventions on domestic horses across a broad range of different contexts of equine care and trainin

Externí odkaz: https://doaj.org/article/4333d01204834a498ac241d02391b410

Optimization of permeability in a series of pyrrolotriazine inhibitors of IRAK4.

Autor: Degorce SL; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, United Kingdom. Electronic address: sebastien.degorce@astrazeneca.com., Anjum R; Bioscience, Oncology, IMED Biotech Unit, AstraZeneca, Boston, 35 Gatehouse Drive, Waltham, MA 02451, United States., Dillman KS; Bioscience, Oncology, IMED Biotech Unit, AstraZeneca, Boston, 35 Gatehouse Drive, Waltham, MA 02451, United States., Drew L; Bioscience, Oncology, IMED Biotech Unit, AstraZeneca, Boston, 35 Gatehouse Drive, Waltham, MA 02451, United States., Groombridge SD; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom., Halsall CT; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom., Lenz EM; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, United Kingdom., Lindsay NA; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, United Kingdom., Mayo MF; Bioscience, Oncology, IMED Biotech Unit, AstraZeneca, Boston, 35 Gatehouse Drive, Waltham, MA 02451, United States., Pink JH; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom., Robb GR; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, United Kingdom., Scott JS; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, United Kingdom., Stokes S; Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, United Kingdom., Xue Y; Discovery Sciences, IMED Biotech Unit, AstraZeneca, Gothenburg SE-431 83, Mölndal, Sweden.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2018 Feb 15; Vol. 26 (4), pp. 913-924. Date of Electronic Publication: 2018 Jan 17.

A small molecule mitigates hearing loss in a mouse model of Usher syndrome III.

Autor: Alagramam KN; Otolaryngology Head and Neck Surgery, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.; Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, USA.; Neurosciences, Case Western Reserve University, Cleveland, Ohio, USA., Gopal SR; Otolaryngology Head and Neck Surgery, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, USA., Geng R; Otolaryngology Head and Neck Surgery, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, USA., Chen DH; Otolaryngology Head and Neck Surgery, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, USA., Nemet I; Pharmacology and Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, Cleveland, Ohio, USA., Lee R; Pharmacology and Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, Cleveland, Ohio, USA., Tian G; Pharmacology and Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, Cleveland, Ohio, USA., Miyagi M; Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, USA., Malagu KF; BioFocus, a Charles River company, Chesterford Research Park, Saffron Walden, UK., Lock CJ; BioFocus, a Charles River company, Chesterford Research Park, Saffron Walden, UK., Esmieu WR; BioFocus, a Charles River company, Chesterford Research Park, Saffron Walden, UK., Owens AP; BioFocus, a Charles River company, Chesterford Research Park, Saffron Walden, UK., Lindsay NA; BioFocus, a Charles River company, Chesterford Research Park, Saffron Walden, UK., Ouwehand K; Charles River Nederland BV, Leiden, the Netherlands., Albertus F; Charles River Nederland BV, Leiden, the Netherlands., Fischer DF; Charles River Nederland BV, Leiden, the Netherlands., Bürli RW; BioFocus, a Charles River company, Chesterford Research Park, Saffron Walden, UK., MacLeod AM; BioFocus, a Charles River company, Chesterford Research Park, Saffron Walden, UK., Harte WE; Office of Translation and Innovation, Case Western Reserve University, Cleveland, Ohio, USA., Palczewski K; Pharmacology and Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, Cleveland, Ohio, USA., Imanishi Y; Pharmacology and Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, Cleveland, Ohio, USA.

Publikováno v: Nature chemical biology [Nat Chem Biol] 2016 Jun; Vol. 12 (6), pp. 444-51. Date of Electronic Publication: 2016 Apr 25.