Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lindsay N. Sausville"'
Autor:
Ambra Pozzi, Scott M. Williams, F. Peter Guengerich, John R. Falck, Jorge H. Capdevila, Megan M. Shuey, James M. Luther, Roy Zent, Shouzuo Wei, Shaojun Mei, Manuel Chiusa, Mahesha H. Gangadhariah, Lindsay N. Sausville
This file contains the primer sequence of CYP2C9* variants (Supplementary Table S1); the SNPs genotyped in the BioVU NSCLC study (Supplementary Table S2); quality control measures of SNPs in the BioVU NSCLC study (Supplementary Table S3); clinical an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308f7412116c1324a40a6f5c93f46538
https://doi.org/10.1158/0008-5472.22426270.v1
https://doi.org/10.1158/0008-5472.22426270.v1
Autor:
Ambra Pozzi, Scott M. Williams, F. Peter Guengerich, John R. Falck, Jorge H. Capdevila, Megan M. Shuey, James M. Luther, Roy Zent, Shouzuo Wei, Shaojun Mei, Manuel Chiusa, Mahesha H. Gangadhariah, Lindsay N. Sausville
Increased expression of cytochrome P450 CYP2C9, together with elevated levels of its products epoxyeicosatrienoic acids (EET), is associated with aggressiveness in cancer. Cytochrome P450 variants CYP2C9*2 and CYP2C9*3 encode proteins with reduced en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff77c3335eea0c969f51ecdd1f48097
https://doi.org/10.1158/0008-5472.c.6512281
https://doi.org/10.1158/0008-5472.c.6512281
Autor:
Lindsay N Sausville, Carissa C Jones, Melinda C Aldrich, William J Blot, Ambra Pozzi, Scott M Williams
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180471 (2017)
Globally, lung cancer results in more deaths worldwide than any other cancer, indicating a need for better treatments. Members of the eicosanoid metabolism pathway represent promising therapeutic targets, as several enzymes involved in the generation
Externí odkaz:
https://doaj.org/article/e65e1a27e0bd491abeee6d52aef21177
Autor:
Marquitta J. White, Cinzia Ciccacci, Lindsay N. Sausville, Scott M. Williams, Alessandra Tacconelli, Giorgio Sirugo, Gloria Tavera, Anders Solitander Bohlbro, Christian Wejse, Rafal S. Sobota, Jasmine M. Olvany
Publikováno v:
Infect Genet Evol
Olvany, J M, Sausville, L N, White, M J, Tacconelli, A, Tavera, G, Sobota, R S, Ciccacci, C, Bohlbro, A S, Wejse, C, Williams, S M & Sirugo, G 2020, ' CLEC4E (Mincle) genetic variation associates with pulmonary tuberculosis in Guinea-Bissau (West Africa) ', Infection, Genetics and Evolution, vol. 85, 104560 . https://doi.org/10.1016/j.meegid.2020.104560
Olvany, J M, Sausville, L N, White, M J, Tacconelli, A, Tavera, G, Sobota, R S, Ciccacci, C, Bohlbro, A S, Wejse, C, Williams, S M & Sirugo, G 2020, ' CLEC4E (Mincle) genetic variation associates with pulmonary tuberculosis in Guinea-Bissau (West Africa) ', Infection, Genetics and Evolution, vol. 85, 104560 . https://doi.org/10.1016/j.meegid.2020.104560
Tuberculosis (TB) is the leading cause of death from a single infectious agent. According to the WHO, 85% of cases in 2018 were pulmonary tuberculosis (PTB), making it the most prevalent form of the disease. Although the bacillus responsible for dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a038bef1630e0c369b6e35c88fcc5b3b
https://pubmed.ncbi.nlm.nih.gov/32971250
https://pubmed.ncbi.nlm.nih.gov/32971250
Autor:
Roy Zent, Mahesha Gangadhariah, James M. Luther, Megan M Shuey, Shaojun Mei, F. Peter Guengerich, Lindsay N. Sausville, Manuel Chiusa, J. Capdevila, Ambra Pozzi, Scott M. Williams, Shouzuo Wei, John R. Falck
Publikováno v:
Cancer Research. 78:4865-4877
Increased expression of cytochrome P450 CYP2C9, together with elevated levels of its products epoxyeicosatrienoic acids (EET), is associated with aggressiveness in cancer. Cytochrome P450 variants CYP2C9*2 and CYP2C9*3 encode proteins with reduced en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f2d5f68adeea617b675dcd6adf17da
https://doi.org/10.1158/0008-5472.can-17-3977
https://doi.org/10.1158/0008-5472.can-17-3977
Autor:
Rafal S. Sobota, Lindsay N. Sausville, Catherine M. Stein, William K. Scott, Giorgio Sirugo, Philip C. Hill, Scott M. Williams, W. Henry Boom, Nicola M. Zetola, Christian Wejse
Publikováno v:
Current Genetic Medicine Reports. 5:149-166
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), remains a major public health threat globally. Several lines of evidence support a role for host genetic factors in resistance/susceptibility to TB disease and MTB infection. However, res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df938a5cac8c26edf15bc53f67f2b4fa
https://doi.org/10.1007/s40142-017-0130-9
https://doi.org/10.1007/s40142-017-0130-9
Publikováno v:
Pharmacologytherapeutics. 196
Cytochrome CYP450 epoxygenases catalyze the epoxidation of polyunsaturated fatty acids including arachidonic acid, eicosapentaenoic acid, and docosahexaenoic acid. The arachidonic acid-derived products are potent pro-angiogenic lipids and promote tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f287c87b3305920438aee6e3bcf49a7f
https://pubmed.ncbi.nlm.nih.gov/30521883
https://pubmed.ncbi.nlm.nih.gov/30521883
Autor:
Carissa C. Jones, William J. Blot, Melinda C. Aldrich, Lindsay N. Sausville, Scott M. Williams, Ambra Pozzi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 7, p e0180471 (2017)
PLoS ONE, Vol 12, Iss 7, p e0180471 (2017)
Globally, lung cancer results in more deaths worldwide than any other cancer, indicating a need for better treatments. Members of the eicosanoid metabolism pathway represent promising therapeutic targets, as several enzymes involved in the generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87118d9b9f6b12edf23edf263150cdf8
http://europepmc.org/articles/PMC5509150
http://europepmc.org/articles/PMC5509150