Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lindsay N. Hayes"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 13035 (2021)
Many types of stressors have an impact on brain development, function, and disease susceptibility including immune stressors, psychosocial stressors, and exposure to drugs of abuse. We propose that these diverse developmental stressors may utilize a
Externí odkaz:
https://doaj.org/article/25cc7da1eac749eebe7d7a278c2ca35d
Autor:
Adriana Ramos, Koko Ishizuka, Ho Namkung, Lindsay N. Hayes, Atsushi Saito, Arisa Hayashida, Rupali Srivastava, Noah Elkins, Trexy Palen, Elisa Carloni, Tsuyoshi Tsujimura, Coleman Calva, Satoshi Ikemoto, Rana Rais, Barbara S. Slusher, Minae Niwa, Toshiaki Saitoh, Eiki Takimoto, Akira Sawa
We report a mechanism that underlies stress-induced cognitive inflexibility at the molecular level. In a mouse model under subacute stress in which deficits in rule shifting tasks were elicited, the nuclear glyceraldehyde dehydrogenase (N-GAPDH) casc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0737842be23afa4b2efef0da56aa7c6
https://doi.org/10.1101/2022.06.21.497065
https://doi.org/10.1101/2022.06.21.497065
Autor:
Lindsay N. Hayes, Kyongman An, Elisa Carloni, Fangze Li, Elizabeth Vincent, Manish Paranjpe, Gül Dölen, Loyal A. Goff, Adriana Ramos, Shin-ichi Kano, Akira Sawa
Recent studies suggested that microglia, the primary brain immune cells, can affect circuit connectivity and neuronal function1–3. Microglia infiltrate the neuroepithelium early in embryonic development and are maintained in the brain throughout ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9973dfeaacd28dd1b64e5e9a94bdebd
https://doi.org/10.1101/2021.12.27.473694
https://doi.org/10.1101/2021.12.27.473694
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13035, p 13035 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Many types of stressors have an impact on brain development, function, and disease susceptibility including immune stressors, psychosocial stressors, and exposure to drugs of abuse. We propose that these diverse developmental stressors may utilize a
Autor:
Juliet Richetto, Flavia Mueller, Urs Meyer, Ulrike Weber-Stadlbauer, Daniela D. Pollak, Alice Zambon, Lindsay N. Hayes, Akira Sawa
Maternal immune activation (MIA) models that are based on administration of the viral mimetic, poly(I:C), are widely used as experimental tools to study neuronal and behavioral dysfunctions in relation to immune-mediated neurodevelopmental disorders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09a76c8b8524b5eece47f43d709c7eb
https://doi.org/10.5167/uzh-180195
https://doi.org/10.5167/uzh-180195
Autor:
Lindsay N. Hayes, Kyongman An, Elisa Carloni, Fangze Li, Elizabeth Vincent, Chloë Trippaers, Manish Paranjpe, Gül Dölen, Loyal A. Goff, Adriana Ramos, Shin-ichi Kano, Akira Sawa
Publikováno v:
Nature. 610(7931)
Recent studies suggested that microglia, the primary brain immune cells, can affect circuit connectivity and neuronal function
Autor:
Pei-Lung Chen, Mikhail V. Pletnikov, Lindsay N. Hayes, Cassandra Obie, Ann E. Pulver, David Valle, A. V. Shevelkin, Gary Steel, Mariela Zeledon, Dimitrios Avramopoulos, Akira Sawa
Publikováno v:
Complex Psychiatry. 2:79-87
Neuregulin 3 (NRG3) is a paralog of NRG1. Genetic studies in schizophrenia demonstrate that risk variants in NRG3 are associated with cognitive and psychotic symptom severity, and several intronic single nucleotide polymorphisms in NRG3 are associate
Autor:
Shin Ichi Kano, Atsushi Kamiya, Minae Niwa, Atsushi Saito, Mari Kondo, Catherine A. Foss, Jennifer M. Coughlin, Daisuke Fukudome, Martin G. Pomper, Travis E. Faust, Brian J. Lee, Akira Sawa, Lindsay N. Hayes
Publikováno v:
Schizophrenia research. 197
Changes in inflammatory cascades have been implicated in the underlying pathophysiology of psychosis. Translocator protein 18 kDa (TSPO) has been used to assess neuroinflammatory processes in psychotic disorders. Nonetheless, it is unclear whether TS
Publikováno v:
Developmental Biology. 374:115-126
Sonic hedgehog (Shh) signaling is critical for various developmental processes including specification of the midbrain dopamine (mDA) neurons in the ventral mesencephalon (vMes). While the timing of Shh and its response gene Gli1 segregates mDA neuro
Autor:
Robert H. Yolken, Katrina Rodriguez, Emily G. Severance, William W. Eaton, Lindsay N. Hayes, Shuojia Yang, Akira Sawa, Teppei Tanaka, Taro Matsuda
Publikováno v:
Neuroscience research. 115
The present study investigated the relationship between exposure to infectious agents and inflammation markers in individuals with schizophrenia (SZ), bipolar disorder (BP), and controls without a psychiatric disorder. We measured plasma levels of an