Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Lindsay Moritz"'
Autor:
Ondrej Sanovec, Michaela Frolikova, Veronika Kraus, Jana Vondrakova, Maryam Qasemi, Daniela Spevakova, Ondrej Simonik, Lindsay Moritz, Drew Lewis Caswell, Frantisek Liska, Lukas Ded, Jiri Cerny, Tomer Avidor-Reiss, Saher Sue Hammoud, Hubert Schorle, Pavla Postlerova, Klaus Steger, Katerina Komrskova
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
There is a well-established link between abnormal sperm chromatin states and poor motility, however, how these two processes are interdependent is unknown. Here, we identified a possible mechanistic insight by showing that Protamine 2, a nuclear DNA
Externí odkaz:
https://doaj.org/article/01217af291054fa2bce783d7e7012b4f
Autor:
Yu-chi Shen, Adrienne Niederriter Shami, Lindsay Moritz, Hailey Larose, Gabriel L. Manske, Qianyi Ma, Xianing Zheng, Meena Sukhwani, Michael Czerwinski, Caleb Sultan, Haolin Chen, Stephen J. Gurczynski, Jason R. Spence, Kyle E. Orwig, Michelle Tallquist, Jun Z. Li, Saher Sue Hammoud
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Whether the adult testis harbours a somatic progenitor population is unknown. Here, the authors provide evidence that the testis interstitial cells expressing the transcription factor Tcf21 maintain adult testis homeostasis during aging, and act as p
Externí odkaz:
https://doaj.org/article/0ad48386d6e94016bc9c108c31f26ee9
Autor:
Lindsay Moritz, Saher Sue Hammoud
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Male fertility throughout life hinges on the successful production of motile sperm, a developmental process that involves three coordinated transitions: mitosis, meiosis, and spermiogenesis. Germ cells undergo both mitosis and meiosis to generate hap
Externí odkaz:
https://doaj.org/article/8b89264461f948ba9b3584fd5d0c1104
Autor:
Yi Sheng, Alan P. Boyle, Ritvija Agrawal, Jun Li, Samantha B. Schon, Kelsey Jorgensen, Yueh-Chiang Hu, Kaushik Ragunathan, Adam G. Diehl, Jayakrishnan Nandakumar, Caleb Sultan, Mashiat Rabbani, Kyle E. Orwig, Sy Redding, Lindsay Moritz, Xianing Zheng, Saher Sue Hammoud, Devon F. Pendlebury
SummaryConventional dogma presumes that protamine-mediated DNA compaction in sperm is achieved by passive electrostatics between DNA and the arginine-rich core of protamines. However, phylogenetic analysis reveals several non-arginine residues that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b38c96e40ad8c1daa5d161f380fe2b2
https://doi.org/10.1101/2021.09.16.460631
https://doi.org/10.1101/2021.09.16.460631
Autor:
Kyle E. Orwig, Caleb Sultan, Jason R. Spence, Michael Czerwinski, Jun Li, Gabriel L. Manske, Michelle D. Tallquist, Adrienne Niederriter Shami, Xianing Zheng, Qianyi Ma, Hailey Larose, Lindsay Moritz, Yu chi Shen, Haolin Chen, Meena Sukhwani, Stephen J. Gurczynski, Saher Sue Hammoud
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Testicular development and function rely on interactions between somatic cells and the germline, but similar to other organs, regenerative capacity declines in aging and disease. Whether the adult testis maintains a reserve progenitor population rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d19a9a7b00da1aafc368201a682197c
http://europepmc.org/articles/PMC8222243
http://europepmc.org/articles/PMC8222243
Tcf21+mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration
Autor:
Meena Sukhwani, Qianyi Ma, Jourdan Clements, Michael Czerwinski, Yu-chi Shen, Haolin Chen, Hailey Larose, Lindsay Moritz, Caleb Sultan, Jun Li, Michelle D. Tallquist, Adrienne Niederriter Shami, Jason R. Spence, Gabriel L. Manske, Saher Sue Hammoud, Kyle E. Orwig, Xianing Zheng
SummaryTesticular development and function relies on interactions between somatic cells and the germline, but similar to other organs, regenerative capacity decline in aging and disease. Whether the adult testis maintains a reserve progenitor populat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5312701c6c4df990870ee23df2d24a1d
https://doi.org/10.1101/2020.05.02.074518
https://doi.org/10.1101/2020.05.02.074518
Autor:
Lindsay Moritz, Hailey Larose, Sue Hammoud, Kyle E. Orwig, Meena Sukhwani, Adrienne Niederriter Shami, Gabriel L. Manske, Qianyi Ma, Xianing Zheng, Jun Li, Yu-chi Shen
Publikováno v:
Fertility and Sterility. 114:e397
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78047a076337683152b69c68a39b3d30
https://doi.org/10.1016/j.fertnstert.2020.08.1164
https://doi.org/10.1016/j.fertnstert.2020.08.1164
Autor:
David L. Tierney, Lindsay Moritz, Abraham Jon Moller, Mahesh Aitha, Alex Bergstrom, Robert A. Bonomo, Amy R. Marts, Michael W. Crowder, Lucien H. Turner, Richard C. Page, Jay C. Nix
Publikováno v:
Biochemistry
This study examines metal binding to metallo-β-lactamase VIM-2, demonstrating the first successful preparation of a Co(II)-substituted VIM-2 analogue. Spectroscopic studies of the half- and fully metal loaded enzymes show that both Zn(II) and Co(II)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf91f4b903333880ab657c88dd7a392
http://europepmc.org/articles/PMC4245990
http://europepmc.org/articles/PMC4245990
Autor:
Saher Sue Hammoud, Gabriel L. Manske, Xianing Zheng, Bethany B. Moore, Michelle D. Tallquist, Caleb Sultan, Adrienne Niederriter Shami, Jun Li, Qianyi Ma, Christopher D. Green, Stephen J. Gurczynski, Lindsay Moritz, Simone Marini
Publikováno v:
Developmental Cell. 46:651-667.e10
Summary Spermatogenesis requires intricate interactions between the germline and somatic cells. Within a given cross section of a seminiferous tubule, multiple germ and somatic cell types co-occur. This cellular heterogeneity has made it difficult to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80249e40682f7c90fed363a74f5e166
https://doi.org/10.1016/j.devcel.2018.07.025
https://doi.org/10.1016/j.devcel.2018.07.025
Autor:
Brian Bennett, Omar Sanyurah, Zahilyn Roche, Michael W. Crowder, Lindsay Moritz, Mahesh Aitha, Indra D. Sahu, Robert M. McCarrick, Gary A. Lorigan
Publikováno v:
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 20(3)
Previous crystallographic and mutagenesis studies have implicated the role of a position-conserved hairpin loop in the metallo-β-lactamases in substrate binding and catalysis. In an effort to probe the motion of that loop during catalysis, rapid-fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd677d4d332342387c07f2444607ebb
https://pubmed.ncbi.nlm.nih.gov/25827593
https://pubmed.ncbi.nlm.nih.gov/25827593