Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lindsay M. Milich"'
Publikováno v:
Acta Neuropathol
Virtually all phases of spinal cord injury pathogenesis, including inflammation, cell proliferation and differentiation, as well as tissue remodeling, are mediated in part by infiltrating monocyte-derived macrophages. It is now clear that these infil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7eee9e63388d6c6dd8b7656c2716c56
https://doi.org/10.1007/s00401-019-01992-3
https://doi.org/10.1007/s00401-019-01992-3
Single-cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord
Autor:
Susana R. Cerqueira, Sofia Benavides, Jae K. Lee, James S. Choi, Lindsay M. Milich, Pantelis Tsoulfas, Christine B. Ryan, Stephanie L. Yahn
Publikováno v:
The Journal of Experimental Medicine
This study uses single-cell RNA sequencing to investigate the transcriptional heterogeneity of all cell types known to comprise the acutely injured spinal cord in mice. The authors investigate both cell subtype heterogeneity and potential signaling i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b053744241673faeddb0f65d4b49631a
http://europepmc.org/articles/PMC8212781
http://europepmc.org/articles/PMC8212781
Single cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord
Autor:
Stephanie L. Yahn, James S. Choi, Christine B. Ryan, Lindsay M. Milich, Pantelis Tsoulfas, Jae K. Lee
The wound healing process that occurs after spinal cord injury is critical for maintaining tissue homeostasis and limiting tissue damage, but eventually results in a scar-like environment that is not conducive to regeneration and repair. A better und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b360b51c572b7772e7b10099f406dfc
Publikováno v:
Glia. 65:883-899
Oligodendrocyte progenitor cells (OPCs) are present throughout the adult brain and spinal cord and can replace oligodendrocytes lost to injury, aging, or disease. Their differentiation, however, is inhibited by myelin debris, making clearance of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::055956f44a0740b570037d733ea6d5d4
https://doi.org/10.1002/glia.23132
https://doi.org/10.1002/glia.23132
Publikováno v:
Acta Neuropathologica. 137:799-800
The original version of the article contains a labeling error in Fig. 2. The boxed molecular description of pro-inflammatory and anti-inflammatory macrophages were switched. Ly6CHi, Cx3Cr1Lo, Ccr2Hi should have been associated with pro-inflammatory m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::511e03db87540c49d3471b88ac4bf41d
https://doi.org/10.1007/s00401-019-02016-w
https://doi.org/10.1007/s00401-019-02016-w
Publikováno v:
Experimental Neurology. 255:113-126
Spinal cord injury (SCI) evokes rapid deleterious and reparative glial reactions. Understanding the triggers for these responses is necessary for designing strategies to maximize repair. This study examined lesion formation and glial responses to vas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044db1c99002d40bcf4174bba5675cab
https://doi.org/10.1016/j.expneurol.2014.02.025
https://doi.org/10.1016/j.expneurol.2014.02.025