Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Lindsay M Snyder"'
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009970 (2021)
Toxoplasma gondii is an orally acquired pathogen that induces strong IFN-γ based immunity conferring protection but that can also be the cause of immunopathology. The response in mice is driven in part by well-characterized MyD88-dependent signaling
Externí odkaz:
https://doaj.org/article/414ff491d4484a61aadcd0d8355b9edc
Autor:
Lindsay M. Snyder, Eric Y. Denkers
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2021)
The gastrointestinal tract is a major portal of entry for many pathogens, including the protozoan parasite Toxoplasma gondii. Billions of people worldwide have acquired T. gondii at some point in their life, and for the vast majority this has led to
Externí odkaz:
https://doaj.org/article/f84488472d4f465b89fa7448944a6dcb
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Vitamin A deficiency (A–) increases morbidity and mortality to gastrointestinal (GI) infection. Blocking retinoid signaling (dominant negative retinoic acid receptor, dnRAR) in intestinal epithelial cells (IEC, IECdnRAR) had no effect on vitamin A
Externí odkaz:
https://doaj.org/article/97ef667eae5f4817947537d34278f6ad
Autor:
Heather L Mercer, Lindsay M Snyder, Claire M Doherty, Barbara A Fox, David J Bzik, Eric Y Denkers
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008572 (2020)
The apicomplexan Toxoplasma gondii induces strong protective immunity dependent upon recognition by Toll-like receptors (TLR)11 and 12 operating in conjunction with MyD88 in the murine host. However, TLR11 and 12 proteins are not present in humans, i
Externí odkaz:
https://doaj.org/article/1158ee5894a54cd9af1900b0919a7d3c
Publikováno v:
ImmunoHorizons. 6:660-670
iToxoplasma gondii/iinduces strong IFN-γ-based immunity. Innate lymphoid cells (ILC), in particular ILC1, are an important innate source of this protective cytokine during infection. Our objective was to determine how MyD88-dependent signaling influ
Autor:
Lindsay M. Snyder, Kaitlin L. McDaniel, Yuan Tian, Cheng-Hsin Wei, Mary J. Kennett, Andrew D. Patterson, A. Catharine Ross, Margherita T. Cantorna
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Vitamin A deficiency affects over 250 million preschool-age children worldwide and is associated with increased childhood mortality and risk of developing enteric infections. Vitamin A deficient (A–) mice developed chronic Citrobacter rodentium inf
Externí odkaz:
https://doaj.org/article/99ca75cde6d54ab0a99d0a4e9abc1f73
Autor:
Adwitia Dey, Joselyn N. Allen, James W. Fraser, Lindsay M. Snyder, Yuan Tian, Limin Zhang, Robert F. Paulson, Andrew Patterson, Margherita T. Cantorna, Pamela A. Hankey-Giblin
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Neurodegeneration is a critical problem in aging populations and is characterized by severe central nervous system (CNS) inflammation. Macrophages closely regulate inflammation in the CNS and periphery by taking on different activation states. The so
Externí odkaz:
https://doaj.org/article/ef4e1224294c4953ab00e676ad87afbf
Autor:
Zhi Chai, Yafei Lyu, Qiuyan Chen, Cheng-Hsin Wei, Lindsay M. Snyder, Veronika Weaver, Aswathy Sebastian, István Albert, Qunhua Li, Margherita T. Cantorna, Catharine Ross
Publikováno v:
Nutrients; Volume 14; Issue 8; Pages: 1563
Vitamin A (VA) deficiency and diarrheal diseases are both serious public health issues worldwide. VA deficiency is associated with impaired intestinal barrier function and increased risk of mucosal infection-related mortality. The bioactive form of V
Autor:
Heather Lynn Mercer, Lindsay M. Snyder, Kayla L. Menard, Claire M. Doherty, David J. Bzik, Barbara A. Fox, Eric Y. Denkers
Publikováno v:
The Journal of Immunology. 206:112.13-112.13
The apicomplexan Toxoplasma gondii induces strong protective immunity in part dependent upon recognition by Toll-like receptors (TLR) 11 and 12 operating in conjunction with MyD88 in the murine host. However, these TLR are not present in humans, prom
Autor:
Barbara A. Fox, Heather L. Mercer, Claire M. Doherty, Eric Y. Denkers, David J. Bzik, Lindsay M. Snyder
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008572 (2020)
PLoS Pathogens
PLoS Pathogens
The apicomplexan Toxoplasma gondii induces strong protective immunity dependent upon recognition by Toll-like receptors (TLR)11 and 12 operating in conjunction with MyD88 in the murine host. However, TLR11 and 12 proteins are not present in humans, i