Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lindsay M Lueptow"'
Autor:
Suhail Khoja, Jenna Lambert, Matthew Nitzahn, Adam Eliav, YuChen Zhang, Mikayla Tamboline, Colleen T. Le, Eram Nasser, Yunfeng Li, Puja Patel, Irina Zhuravka, Lindsay M. Lueptow, Ilona Tkachyova, Shili Xu, Itzhak Nissim, Andreas Schulze, Gerald S. Lipshutz
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 278-296 (2022)
Creatine deficiency disorders are inborn errors of creatine metabolism, an energy homeostasis molecule. One of these, guanidinoacetate N-methyltransferase (GAMT) deficiency, has clinical characteristics that include features of autism, self-mutilatio
Externí odkaz:
https://doaj.org/article/87a7fdb6ecd04a129c24284a36c20cca
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Anxiety disorders are prevalent across the United States and result in a large personal and societal burden. Currently, numerous therapeutic and pharmaceutical treatment options exist. However, drugs to classical receptor targets have shown limited e
Externí odkaz:
https://doaj.org/article/b50b925463e04c24ac1e7d35123b7843
Autor:
Lindsay M Lueptow, Bill Tawil
Publikováno v:
Journal of Applied Biotechnology & Bioengineering. 10:37-43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7197d360afa0989e742d8e36b59c0acb
https://doi.org/10.15406/jabb.2023.10.00325
https://doi.org/10.15406/jabb.2023.10.00325
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Opioids remain among the most effective pain-relieving therapeutics. However, their long-term use is limited due to the development of tolerance and potential for addiction. For many years, researchers have explored the underlying mechanisms that lea
Externí odkaz:
https://doaj.org/article/90547a75d12e4ecc8c1b339cb493d177
Autor:
Catherine M. Cahill, Lindsay M. Lueptow, Raj Shusharla, Christopher J. Evans, Hannah Kim, Amy Bishop
Publikováno v:
Handb Exp Pharmacol
The Kappa Opioid Receptor ISBN: 9783030890735
The Kappa Opioid Receptor ISBN: 9783030890735
Pain is complex and is a unique experience for individuals in that no two people will have exactly the same physiological and emotional response to the same noxious stimulus or injury. Pain is composed of two essential processes: a sensory component
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4430700f4d540c584d9c70bfa14b5f4
https://escholarship.org/uc/item/7sz581x8
https://escholarship.org/uc/item/7sz581x8
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience
Frontiers in Neuroscience
Anxiety disorders are prevalent across the United States and result in a large personal and societal burden. Currently, numerous therapeutic and pharmaceutical treatment options exist. However, drugs to classical receptor targets have shown limited e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ce7873653afe750dc6a97f70d7545b
https://doi.org/10.3389/fnins.2021.675769
https://doi.org/10.3389/fnins.2021.675769
Autor:
Anna M.W. Taylor, Lindsay M. Lueptow, F. Ivy Carroll, Inés Ibarra-Lecue, Tuan Trang, Joshua K. Hakimian, Kristina Komarek, Frances M. Leslie, Anne M. Andrews, Amie L. Severino, Shiwei Liu, Sarah Pickens, Caroline E. Bass, Hongyan Yang, Christopher Cook, Wendy Walwyn, Nicole E. Burma, Catherine M. Cahill, Christopher J. Evans, Lihua Xue, Mary C. Olmstead
Publikováno v:
The Journal of Neuroscience. 39:4162-4178
Pain is a multidimensional experience and negative affect, or how much the pain is “bothersome”, significantly impacts the sufferers' quality of life. It is well established that the κ opioid system contributes to depressive and dysphoric states
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc1261998e9ee0cceb5a4b87748a261
https://doi.org/10.1523/jneurosci.0274-19.2019
https://doi.org/10.1523/jneurosci.0274-19.2019
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0631c6aab56bc9e4c8b805bad3d3997
https://doi.org/10.1096/fasebj.2021.35.s1.02980
https://doi.org/10.1096/fasebj.2021.35.s1.02980
Autor:
Adrianne R. Wilson-Poe, Jose A. Morón, Cherkaouia Kibaly, Beth Wiese, Catherine M. Cahill, Preeti Anand, Jeniffer J. Garcia, Lindsay M. Lueptow
Publikováno v:
Pain Reports
PAIN Reports, Vol 6, Iss 1, p e897 (2021)
Pain reports, vol 6, iss 1
PAIN Reports, Vol 6, Iss 1, p e897 (2021)
Pain reports, vol 6, iss 1
Western blot and GTPγS analyses reveal inflammatory pain–induced adaptations in the midbrain periaqueductal gray, which is critically involved in descending pain modulation. Pain upregulates the expression of the CB1 receptor and increases G-prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ece5453b99fe8b0ec73879ee7c13459
http://europepmc.org/articles/PMC7939232
http://europepmc.org/articles/PMC7939232
Autor:
Margaret G Miller, Lindsay M. Lueptow, Catherine M. Cahill, Elizabeth C Shashkova, Christopher J. Evans
Publikováno v:
Current anesthesiology reports, vol 10, iss 4
Curr Anesthesiol Rep
Curr Anesthesiol Rep
PURPOSE OF REVIEW: Opioids remain the most potent form of pain relief currently available, yet have a high abuse liability. Here we discuss underlying neurobiological changes in Opioid Use Disorder (OUD) that likely contribute to drug craving, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1b20859f8a0b1f8b6fe97b513f1422
https://escholarship.org/uc/item/8mm69086
https://escholarship.org/uc/item/8mm69086