Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Lindsay Lundberg"'
Autor:
Lindsay Lundberg, Jacque Fontenot, Shih-Chao Lin, Chelsea Pinkham, Brian D. Carey, Catherine E. Campbell, Kylene Kehn-Hall
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Venezuelan equine encephalitis virus (VEEV) is a positive sense, single-stranded RNA virus and member of the New World alphaviruses. It causes a biphasic febrile illness that can be accompanied by central nervous system involvement and moderate morbi
Externí odkaz:
https://doaj.org/article/a967b9a20c384889b9424684be410d02
Autor:
Lindsay Lundberg, Chelsea Pinkham, Cynthia de la Fuente, Ashwini Brahms, Nazly Shafagati, Kylie M Wagstaff, David A Jans, Sharon Tamir, Kylene Kehn-Hall
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 11, p e0005122 (2016)
The capsid structural protein of the New World alphavirus, Venezuelan equine encephalitis virus (VEEV), interacts with the host nuclear transport proteins importin α/β1 and CRM1. Novel selective inhibitor of nuclear export (SINE) compounds, KPT-185
Externí odkaz:
https://doaj.org/article/6ee7079ab4dd440c80b3aad825d36fab
Autor:
Todd M. Bell, Virginia Espina, Lindsay Lundberg, Chelsea Pinkham, Ashwini Brahms, Brian D. Carey, Shih-Chao Lin, Bibha Dahal, Caitlin Woodson, Cynthia de la Fuente, Lance A. Liotta, Charles L. Bailey, Kylene Kehn-Hall
Publikováno v:
Viruses, Vol 10, Iss 4, p 191 (2018)
Viruses must parasitize host cell translational machinery in order to make proteins for viral progeny. In this study, we sought to use this signal transduction conduit against them by inhibiting multiple kinases that influence translation. Previous w
Externí odkaz:
https://doaj.org/article/6039e7714e9144469310bb7ca084488b
Autor:
Nazly Shafagati, Lindsay Lundberg, Alan Baer, Alexis Patanarut, Katherine Fite, Benjamin Lepene, Kylene Kehn-Hall
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128215 (2015)
Rift Valley fever virus (RVFV) is a highly pathogenic arthropod-borne virus that has a detrimental effect on both livestock and human populations. While there are several diagnostic methodologies available for RVFV detection, many are not sensitive e
Externí odkaz:
https://doaj.org/article/29dcdfb0b2fe41d1b4f098d47465d301
Publikováno v:
Viruses, Vol 9, Iss 10, p 279 (2017)
Venezuelan equine encephalitis virus (VEEV) is a New World alphavirus that is vectored by mosquitos and cycled in rodents. It can cause disease in equines and humans characterized by a febrile illness that may progress into encephalitis. Like the cap
Externí odkaz:
https://doaj.org/article/5231f6ed96b549159a53cd85c841dda5
Autor:
Dana Austin, Alan Baer, Lindsay Lundberg, Nazly Shafagati, Annalise Schoonmaker, Aarthi Narayanan, Taissia Popova, Jean Jacques Panthier, Fatah Kashanchi, Charles Bailey, Kylene Kehn-Hall
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36327 (2012)
Rift Valley fever virus (RVFV) is an emerging viral zoonosis that is responsible for devastating outbreaks among livestock and is capable of causing potentially fatal disease in humans. Studies have shown that upon infection, certain viruses have the
Externí odkaz:
https://doaj.org/article/18754295d1b048c0a9f6e162e78beb36
Autor:
Kylene Kehn-Hall, Aarthi Narayanan, Lindsay Lundberg, Gavin Sampey, Chelsea Pinkham, Irene Guendel, Rachel Van Duyne, Svetlana Senina, Kimberly L Schultz, Eric Stavale, M Javad Aman, Charles Bailey, Fatah Kashanchi
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34761 (2012)
Alphaviruses, including Venezuelan Equine Encephalitis Virus (VEEV), cause disease in both equine and humans that exhibit overt encephalitis in a significant percentage of cases. Features of the host immune response and tissue-specific responses may
Externí odkaz:
https://doaj.org/article/a88941b1091b4188b28cdceedc7b7130
Autor:
David A. Jans, Lindsay Lundberg, Kylie M. Wagstaff, Sharon Shechter, David R. Thomas, Kylene Kehn-Hall, Shih-Chao Lin, Chelsea Pinkham, Aaron DeBono
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports
Scientific Reports
Therapeutics are currently unavailable for Venezuelan equine encephalitis virus (VEEV), which elicits flu-like symptoms and encephalitis in humans, with an estimated 14% of cases resulting in neurological disease. Here we identify anti-VEEV agents us
Autor:
Neha Bansal, Lindsay Lundberg, Aarthi Narayanan, Kylene Kehn-Hall, Soyeon An, Chelsea Pinkham, Ashwini Benedict
Publikováno v:
Virology. 496:175-185
Rift Valley fever (RVF) is a zoonotic disease that can cause severe illness in humans and livestock, triggering spontaneous abortion in almost 100% of pregnant ruminants. In this study, we demonstrate that signal transducer and activator of transcrip
Autor:
Danielle Swales, Lindsay Lundberg, Nicole Waybright, Jonathan L. Jacobs, Chelsea Pinkham, Kylene Kehn-Hall, Alan Baer, Jonathan D. Dinman
Publikováno v:
Journal of Virology
Venezuelan equine encephalitis virus (VEEV) is a previously weaponized arthropod-borne virus responsible for causing acute and fatal encephalitis in animal and human hosts. The increased circulation and spread in the Americas of VEEV and other enceph