Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Lindsay LeBaron"'
Autor:
Frank Porreca, Chaoling Qu, Lindsay LeBaron, Yeon Sun Lee, Cyf Ramos-Colon, Victor J. Hruby, Jennifer Y. Xie, Sara M. Hall, Josephine Lai
Publikováno v:
ACS Chemical Neuroscience. 7:1746-1752
Dynorphin A (Dyn A) is a unique endogenous ligand that possesses well-known neuroinhibitory effects via opioid receptors with a preference for the kappa receptor but also neuroexcitatory effects, which cause hyperalgesia. We have shown that the neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::919cd1c40e2825eec312b2b397bea5ad
https://doi.org/10.1021/acschemneuro.6b00258
https://doi.org/10.1021/acschemneuro.6b00258
Autor:
Ann Nguyen, Michael Remesic, Frank Porreca, Victor J. Hruby, David Rankin, Cyf Ramos-Colon, Lindsay LeBaron, Yeon Sun Lee, Sara M. Hall, Josephine Lai
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:30-33
It has been shown that under chronic pain or nerve injury conditions, up-regulated dynorphin A (Dyn A) interacts with bradykinin receptors (BRs) to cause hyperalgesia in the spinal cord. Thus BRs antagonist can modulate hyperalgesia by blocking Dyn A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c07cfebda0e4078ede1b61566162e4e
https://doi.org/10.1016/j.bmcl.2014.11.026
https://doi.org/10.1016/j.bmcl.2014.11.026