Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Lindsay Kilburn"'
Autor:
Erin R. Bonner, Robin Harrington, Augustine Eze, Miriam Bornhorst, Cassie N. Kline, Heather Gordish-Dressman, Adam Dawood, Biswajit Das, Li Chen, Rini Pauly, P. Mickey Williams, Chris Karlovich, Amanda Peach, D’andra Howell, James Doroshow, Lindsay Kilburn, Roger J. Packer, Sabine Mueller, Javad Nazarian
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-6 (2022)
Abstract Molecular profiling of childhood CNS tumors is critical for diagnosis and clinical management, yet tissue access is restricted due to the sensitive tumor location. We developed a targeted deep sequencing platform to detect tumor driver mutat
Externí odkaz:
https://doaj.org/article/9e314be8330c4153b226c12c059956f7
Autor:
Eric W. Prince, Ros Whelan, David M. Mirsky, Nicholas Stence, Susan Staulcup, Paul Klimo, Richard C. E. Anderson, Toba N. Niazi, Gerald Grant, Mark Souweidane, James M. Johnston, Eric M. Jackson, David D. Limbrick, Amy Smith, Annie Drapeau, Joshua J. Chern, Lindsay Kilburn, Kevin Ginn, Robert Naftel, Roy Dudley, Elizabeth Tyler-Kabara, George Jallo, Michael H. Handler, Kenneth Jones, Andrew M. Donson, Nicholas K. Foreman, Todd C. Hankinson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Deep learning (DL) is a widely applied mathematical modeling technique. Classically, DL models utilize large volumes of training data, which are not available in many healthcare contexts. For patients with brain tumors, non-invasive diagnosi
Externí odkaz:
https://doaj.org/article/48a196a679684d488c084efeeb434cda
Autor:
Eric Prince, Ros Whelan, Andrew Donson, Susan Staulcup, Astrid Hengartner, Trinka Vijmasi, Chibueze Agwu, Kevin O. Lillehei, Nicholas K. Foreman, James M. Johnston, Luca Massimi, Richard C. E. Anderson, Mark M. Souweidane, Robert P. Naftel, David D. Limbrick, Gerald Grant, Toba N. Niazi, Roy Dudley, Lindsay Kilburn, Eric M. Jackson, George I. Jallo, Kevin Ginn, Amy Smith, Joshua J. Chern, Amy Lee, Annie Drapeau, Mark D. Krieger, Michael H. Handler, Todd C. Hankinson, on behalf of the Advancing Treatment for Pediatric Craniopharyngioma Consortium
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-10 (2020)
Abstract Adamantinomatous craniopharyngioma (ACP) is a biologically benign but clinically aggressive lesion that has a significant impact on quality of life. The incidence of the disease has a bimodal distribution, with peaks occurring in children an
Externí odkaz:
https://doaj.org/article/a32c5645c0614369aacbf5d325ac568d
Autor:
Sulgi Lee, Madhuri Kambhampati, M. Isabel Almira-Suarez, Cheng-Ying Ho, Eshini Panditharatna, Seth I. Berger, Joyce Turner, David Van Mater, Lindsay Kilburn, Roger J. Packer, John S. Myseros, Eric Vilain, Javad Nazarian, Miriam Bornhorst
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
Anaplastic astrocytomas are aggressive glial cancers that present poor prognosis and high recurrence. Heterozygous IDH1 R132H mutations are common in adolescent and young adult anaplastic astrocytomas. In a majority of cases, the IDH1 R132H mutation
Externí odkaz:
https://doaj.org/article/d2bac8e5f1d44d029b2c7bb1a8cc5b82
Autor:
Hasan R. Syed, Lindsay Kilburn, Adriana Fonseca, Javad Nazarian, Chima Oluigbo, John S. Myseros, Roger J. Packer, Robert F. Keating
Publikováno v:
Journal of Neuro-Oncology. 162:449-451
Autor:
Sabine Mueller, Javad Nazarian, Sebastian M. Waszak, Adam Resnick, Michael Prados, Annette Molinaro, Michael Berens, Sara Byron, Winnie Liang, John Kuhn, Adam Kraya, Jo Lynne Rokita, Krutika S. Gaonkar, Bo Zhang, Sridevi Yadavilli, Jie Zhang, Madhuri Kambhampati, Yalan Zhang, Tracy Luks, Javier Villanueva-Meyer, Roger J. Packer, Anu Banerjee, John R. Crawford, Nalin Gupta, Erin R. Bonner, Lindsay Kilburn, Payal Jain, Cassie Kline
Purpose:PNOC003 is a multicenter precision medicine trial for children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG).Patients and Methods:Patients (3–25 years) were enrolled on the basis of imaging consistent with DI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd015a3199b4df3ee68f96b784b3d48
https://doi.org/10.1158/1078-0432.c.6532295
https://doi.org/10.1158/1078-0432.c.6532295
Autor:
Sabine Mueller, Javad Nazarian, Sebastian M. Waszak, Adam Resnick, Michael Prados, Annette Molinaro, Michael Berens, Sara Byron, Winnie Liang, John Kuhn, Adam Kraya, Jo Lynne Rokita, Krutika S. Gaonkar, Bo Zhang, Sridevi Yadavilli, Jie Zhang, Madhuri Kambhampati, Yalan Zhang, Tracy Luks, Javier Villanueva-Meyer, Roger J. Packer, Anu Banerjee, John R. Crawford, Nalin Gupta, Erin R. Bonner, Lindsay Kilburn, Payal Jain, Cassie Kline
Supplementary Figure from Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019d2fe800b2e02f3568ddd329dc848f
https://doi.org/10.1158/1078-0432.22486334.v1
https://doi.org/10.1158/1078-0432.22486334.v1
Autor:
Margot A Lazow, Martijn T Nievelstein, Adam Lane, Pratiti Bandopadhayhay, Mariko DeWire-Schottmiller, Maryam Fouladi, John W Glod, Robert J Greiner, Lindsey M Hoffman, Trent R Hummel, Lindsay Kilburn, Sarah Leary, Jane E Minturn, Roger Packer, David S Ziegler, Brooklyn Chaney, Katie Black, Peter de Blank, James L Leach
Publikováno v:
Neuro Oncol
Background Cross-sectional tumor measures are traditional clinical trial endpoints; however volumetric measures may better assess tumor growth. We determined the correlation and compared the prognostic impact of cross-sectional and volumetric measure
Autor:
Jane E. Minturn, Ayman El-Sheikh, Gustavo Sevlever, Michelle Monje-Deisseroth, Hetal Dholaria, Karen Tsui, Maryam Fouladi, Pratiti Bandopadhayay, Cynthia Hawkins, Scott L Coven, Lindsay Kilburn, Christopher L. Tinkle, David S. Ziegler, Eric Sandler, Yvan Samson, Jordan R. Hansford, Eric Bouffet, Sylvia Cheng, Sridharan Gururangan, Kathleen Dorris, Tim Hassall, Mohamed S. Zaghloul, Carl Koschmann, Sarah Leary, Mercedes Garcia Lombardi, Blaise V. Jones, Paul G. Fisher, Anthony Asher, Rachid Drissi, Blanca Diez, Kenneth J. Cohen, Jie Ma, Adriana Fonseca, Katie Black, Nicholas G. Gottardo, Stewart Goldman, Christine E. Fuller, Tabitha Cooney, Moatasem El-Ayadi, Adam Lane, Brooklyn Chaney, Mariko DeWire, Robert J. Greiner, Ute Bartels, Margot A Lazow, James L. Leach, Lars M. Wagner, Roger J. Packer
Publikováno v:
Neuro Oncol
Background Diffuse intrinsic pontine glioma (DIPG) remains a clinico-radiologic diagnosis without routine tissue acquisition. Reliable imaging distinction between DIPG and other pontine tumors with potentially more favorable prognoses and treatment c
Autor:
Nirali Patel, Kathleen Felton, Surajit Bhattacharya, Maria Isabel Almira-Suarez, Augustine Eze, Joyce Turner, Robert Keating, Chima Oluigbo, Reuven J. Schore, Lindsay Kilburn, Roger J. Packer, John S. Myseros, Miriam Bornhorst
Publikováno v:
Journal of neurosurgery. Pediatrics.
OBJECTIVE Li-Fraumeni syndrome (LFS) is a cancer predisposition syndrome caused by germline mutations in the TP53 gene. CNS tumors are the fourth most common tumor type in LFS, and recent screening guidelines demonstrate that early tumor detection is