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pro vyhledávání: '"Lindsay Juriga"'
Autor:
Pan‐Fen Wang, Anshuman Sharma, Michael Montana, Alicia Neiner, Lindsay Juriga, Kavya Narayana Reddy, Dani Tallchief, Jane Blood, Evan D. Kharasch
Publikováno v:
British Journal of Clinical Pharmacology. 88:4881-4893
Methadone metabolism and clearance are determined principally by polymorphic cytochrome P4502B6 (CYP2B6). Some CYP2B6 allelic variants affect methadone metabolism in vitro and disposition in vivo. We assessed methadone metabolism by CYP2B6 minor vari
Publikováno v:
Anesthesiology. 130:936-945
Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Opioids are a mainstay of perioperative analgesia. Opioid use in children with obstructive sleep apnea is challenging because of assumption