Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lindsay J Georgopoulos"'
Autor:
Stephanie L Swift, Guillermo C Rivera, Vincent Dussupt, Regina M Leadley, Lucy C Hudson, Corrina Ma de Ridder, Robert Kraaij, Julie E Burns, Norman J Maitland, Lindsay J Georgopoulos
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65557 (2013)
Gene therapy represents an attractive strategy for the non-invasive treatment of prostate cancer, where current clinical interventions show limited efficacy. Here, we evaluate the use of the insect virus, baculovirus (BV), as a novel vector for human
Externí odkaz:
https://doaj.org/article/2b44e3f412824eb893a9ff1215f03de6
Autor:
Norman J. Maitland, Alastair Droop, Katrin Tiemann, Helen J. Rippon, Davide Pellacani, Lindsay J. Georgopoulos, Guillermo C. Rivera-Gonzalez
Publikováno v:
Nucleic Acids Research
In the human prostate, expression of prostate-specific genes is known to be directly regulated by the androgen–induced stimulation of the androgen receptor (AR). However, less is known about the expression control of the prostate-restricted TGM4 (h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978051089b102bd665bd674d9d7b0e62
http://europepmc.org/articles/PMC3367184
http://europepmc.org/articles/PMC3367184
Autor:
Guillermo C. Rivera-Gonzalez, Vincent Dussupt, Norman J. Maitland, Lindsay J. Georgopoulos, Stephanie L. Swift
Publikováno v:
Journal of Invertebrate Pathology. 107:S59-S70
Prostate cancer is the most commonly diagnosed cancer in ageing men in the western world. While the primary cancers can be treated with androgen ablation, radiotherapy and surgery, recurrent castration resistant cancers have an extremely poor prognos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df4496927f0cfd5ffdbd927d44e25b52
https://doi.org/10.1016/j.jip.2011.05.006
https://doi.org/10.1016/j.jip.2011.05.006
Autor:
Karen F. Chambers, Lindsay J. Georgopoulos, Corrina M.A. de Ridder, Magnus Essand, Angelika Danielsson, Chris H. Bangma, Regina M. Leadley, Helen Evans, Wytske M. van Weerden, Martha Simpson-Holley, Robert Kraaij, Norman J. Maitland
Publikováno v:
Human Gene Therapy, 21(7), 815-827. Mary Ann Liebert Inc.
Destruction of cancer cells by genetically modified viral and nonviral vectors has been the aim of many research programs. The ability to target cytotoxic gene therapies to the cells of interest is an essential prerequisite, and the treatment has alw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4f252c055bfb9094d4a455834ef62aa
https://doi.org/10.1089/hum.2009.210
https://doi.org/10.1089/hum.2009.210
Autor:
Julie E. Burns, Stephanie L. Swift, Vincent Dussupt, Lindsay J. Georgopoulos, Robert Kraaij, Guillermo C. Rivera, Norman J. Maitland, Regina M. Leadley, Lucy C. Hudson, Corrina M.A. de Ridder
Publikováno v:
PLoS One (print), 8(6). Public Library of Science
PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e65557 (2013)
PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e65557 (2013)
Gene therapy represents an attractive strategy for the non-invasive treatment of prostate cancer, where current clinical interventions show limited efficacy. Here, we evaluate the use of the insect virus, baculovirus (BV), as a novel vector for human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122cf6b72c929e4325668e13fe2d209f
https://hdl.handle.net/1765/73649
https://hdl.handle.net/1765/73649
Autor:
Munitta Muthana, Bernard Burke, Lindsay J. Georgopoulos, Peter Hoskin, Julian L Burton, Hsin-Yu Fang, Neil Cross, Fiona Morrow, Roshna Mistry, Simon D. Scott, Craig Murdoch, Norman J. Maitland, Seth B. Coffelt, Athina Giannoudis, F.C. Hamdy, Magnus Essand, Nicola J. Brown, Claire E. Lewis
Publikováno v:
Cancer research. 71(5)
New therapies are required to target hypoxic areas of tumors as these sites are highly resistant to conventional cancer therapies. Monocytes continuously extravasate from the bloodstream into tumors where they differentiate into macrophages and accum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffda300c727023209e2d5f56bb420ce7
https://pubmed.ncbi.nlm.nih.gov/21233334
https://pubmed.ncbi.nlm.nih.gov/21233334
Publikováno v:
Innovation through Knowledge Transfer ISBN: 9783642145933
A much-favoured strategy to strengthen the UK economy is to exploit more of the world-class research being carried out in universities. This requires increased collaboration between universities and the industry sector and will benefit enormously fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d302af039a5fbb3872e5b1b33289faf5
https://doi.org/10.1007/978-3-642-14594-0_24
https://doi.org/10.1007/978-3-642-14594-0_24
Autor:
Ellen, Schenk, Magnus, Essand, Chris H, Bangma, Chris, Barber, Jean-Paul, Behr, Simon, Briggs, Robert, Carlisle, Wing-Shing, Cheng, Angelika, Danielsson, Iris J C, Dautzenberg, Helena, Dzojic, Patrick, Erbacher, Kerry, Fisher, April, Frazier, Lindsay J, Georgopoulos, Rob, Hoeben, Stefan, Kochanek, Daniela, Koppers-Lalic, Robert, Kraaij, Florian, Kreppel, Leif, Lindholm, Maria, Magnusson, Norman, Maitland, Patrick, Neuberg, Berith, Nilsson, Manfred, Ogris, Jean-Serge, Remy, Michelle, Scaife, Erik, Schooten, Len, Seymour, Thomas, Totterman, Taco G, Uil, Karel, Ulbrich, Joke L M, Veldhoven-Zweistra, Jeroen, de Vrij, Wytske, van Weerden, Ernst, Wagner, Ralph, Willemsen
Publikováno v:
Human gene therapy. 21(7)
Prostate cancer is at present the most common malignancy in men in the Western world. When localized to the prostate, this disease can be treated by curative therapy such as surgery and radiotherapy. However, a substantial number of patients experien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c414325be1d7717ec4c110b2250ac4a8
https://pubmed.ncbi.nlm.nih.gov/20001452
https://pubmed.ncbi.nlm.nih.gov/20001452
Autor:
Vincent Dussupt, Lindsay J. Georgopoulos, Thomas H. Tötterman, Bo Nilsson, Norman J. Maitland, Graciela Elgue, John D. Lambris, Paola Magotti, Javier Sanchez
Publikováno v:
Molecular immunology. 46(15)
Interactions of gene therapy vectors with human blood components upon intravenous administration have a significant effect on vector efficacy and patient safety. Here we describe methods to evaluate these interactions and their effects in whole human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4671236c35af5ebb4e53c580a5826593
https://pubmed.ncbi.nlm.nih.gov/19665799
https://pubmed.ncbi.nlm.nih.gov/19665799
Publikováno v:
BMC Genomics, Vol 10, Iss 1, p 67 (2009)
BMC Genomics
BMC Genomics, 10 p. 67. (2009)
BMC Genomics
BMC Genomics, 10 p. 67. (2009)
Background Cells transformed by human adenoviruses (Ad) exhibit differential capacities to induce tumours in immunocompetent rodents; for example, Ad12-transformed rodent cells are oncogenic whereas Ad5-transformed cells are not. The E1A gene determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77651b72e36ac6554a66679a697de628
http://www.biomedcentral.com/1471-2164/10/67
http://www.biomedcentral.com/1471-2164/10/67