Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lindsay Heyd"'
Autor:
Hong Ma, Andrea Wecker, Marianne Kearney, Marcy Silver, Toyoaki Murohara, Tina Thorne, Mary Gavin, Satoshi Shintani, Lindsay Heyd, Masaaki, Douglas W. Losordo, Kengo Fukushima Kusano, Cynthia Curry, Atsushi Iwakura
Publikováno v:
Nature Clinical Practice Cardiovascular Medicine. 3:S123-S128
Previous studies have shown that local angiogenic gene therapy acts, in part, by recruiting endothelial progenitor cells (EPCs) to ischemic tissue. Recent data indicate that patients with the most severe vascular disease may have insufficient or defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1671a142e2528f10f9ca72bb282c7c6
https://doi.org/10.1038/ncpcardio0430
https://doi.org/10.1038/ncpcardio0430
Autor:
Deepika Dinesh, Hong Ma, Takayuki Asahara, Yan Zhu, Masaaki, Lindsay Heyd, Mary Gavin, David A. Goukassian, Marcy Silver, Gangjian Qin, Liz Eaton, Raj Kishore, Young Sup Yoon, Thalia Papayannopoulou, Evelyn Bord, Douglas W. Losordo, Tina Thorne, Marianne Kearney, Andrea Wecker, Cynthia Curry
Publikováno v:
The Journal of Experimental Medicine
The cell surface receptor alpha4 integrin plays a critical role in the homing, engraftment, and maintenance of hematopoietic progenitor cells (HPCs) in the bone marrow (BM). Down-regulation or functional blockade of alpha4 integrin or its ligand vasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636615cc0a48f7b96f58bfb8a94a5ce4
https://doi.org/10.1084/jem.20050459
https://doi.org/10.1084/jem.20050459
Autor:
Sudha Sinha, Marianne Kearney, Donato Sodano, Janice Flanagan, Kian Keong Poh, Cindy Ouilette, Robert Weinstein, Douglas W. Losordo, Lindsay Heyd, Jill Wollins
Publikováno v:
Journal of Clinical Apheresis. 21:116-120
Information on the safety of mobilization and collection of peripheral blood progenitor cells (PBPC) in patients with advanced coronary heart disease (CHD) is limited. We report herein our early experience with patients participating in a Phase I tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e398af1a74105f3a0e562c1bba06b403
https://doi.org/10.1002/jca.20075
https://doi.org/10.1002/jca.20075
Autor:
Young-sup Yoon, Andrea Wecker, Lindsay Heyd, Jong-Seon Park, Tengiz Tkebuchava, Kengo Kusano, Allison Hanley, Heather Scadova, Gangjian Qin, Dong-Hyun Cha, Kirby L. Johnson, Ryuichi Aikawa, Takayuki Asahara, Douglas W. Losordo
Publikováno v:
Journal of Clinical Investigation. 115:326-338
We have identified a subpopulation of stem cells within adult human BM, isolated at the single-cell level, that self-renew without loss of multipotency for more than 140 population doublings and exhibit the capacity for differentiation into cells of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7f50d4b66edfa08f23b76b46e98ec4
https://doi.org/10.1172/jci200522326
https://doi.org/10.1172/jci200522326
Autor:
Timothy D. Henry, Douglas W. Losordo, Pinak B. Shah, Ken Story, Rachel E. Olson, Aaron Burg, Michelle Durgin, Jay H. Traverse, Christopher J. White, Victor Zak, Donata Sodano, Liz Eaton, Atsuhiko Kawamoto, Janice Flanagan, Peter A Soukas, Robert Weinstein, Douglas Dowling, Marianne Kearney, Lindsay Heyd, Kengo Fukushima Kusano, James E. Udelson, Vimal Veereshwarayya, Richard A. Schatz, Tina Thorne, Takayuki Asahara, Kian Keong Poh, Frederick G.P. Welt, Muqtada Chaudhry, Leon Shturman, Jill Wollins, Peter Hoffmeister, Toshinori Murayama
Publikováno v:
Circulation. 115(25)
Background— A growing population of patients with coronary artery disease experiences angina that is not amenable to revascularization and is refractory to medical therapy. Preclinical studies have indicated that human CD34 + stem cells induce neov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a523aada9396c1fad5590e7f64f13e
https://pubmed.ncbi.nlm.nih.gov/17562958
https://pubmed.ncbi.nlm.nih.gov/17562958
Autor:
Douglas W. Losordo, Corinne Luedemann, Marcy Silver, Tina Thorne, David A. Goukassian, Deepika Dinesh, Gangjian Qin, Allison Hanley, Raj Kishore, Marianne Kearney, Fabio Martelli, Cynthia Curry, Toshinori Murayama, Yan Zhu, Lindsay Heyd, Christine Dolan, Andrea Wecker
The transcription factor E2F1 is known to regulate cell proliferation and has been thought to modulate tumorigenesis via this mechanism alone. Here we show that mice deficient in E2F1 exhibit enhanced angiogenesis. The proangiogenic phenotype in E2F1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f3ddeaa3354d32b8923fe5f690ccf4
https://europepmc.org/articles/PMC1544166/
https://europepmc.org/articles/PMC1544166/
Autor:
Ryuichi Aikawa, Hideya Takenaka, Hiromichi Hamada, Marianne Kearney, David A. Goukassian, Young Sup Yoon, Jeffery A. Porter, Elizabeth Eaton, Satoshi Shintani, Tengiz Tkebuchava, Masaaki, Lindsay Heyd, Raj Kishore, Tina Thorne, Jun Asai, William E. Munger, Hong Ma, Atsuhiko Kawamoto, Douglas W. Losordo, Cynthia Curry, Atsushi Iwakura, Kengo Fukushima Kusano, Roberto Pola, Patrick von Samson, Marcy Silver, Toshinori Murayama
Publikováno v:
Nature medicine. 11(11)
Sonic hedgehog (Shh) is a crucial regulator of organ development during embryogenesis. We investigated whether intramyocardial gene transfer of naked DNA encoding human Shh (phShh) could promote a favorable effect on recovery from acute and chronic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e6e96c3da3947c5fbb20f7680c5ecc
https://pubmed.ncbi.nlm.nih.gov/16244652
https://pubmed.ncbi.nlm.nih.gov/16244652