Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Lindsay E. Nyhoff"'
Autor:
Devyani Joshi, Lindsay E. Nyhoff, Veronika I. Zarnitsyna, Alberto Moreno, Kelly Manning, Susanne Linderman, Allison R. Burrell, Kathy Stephens, Carson Norwood, Grace Mantus, Rafi Ahmed, Evan J. Anderson, Mary A. Staat, Mehul S. Suthar, Jens Wrammert
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107967- (2023)
Summary: As SARS-CoV-2 becomes endemic, it is critical to understand immunity following early-life infection. We evaluated humoral responses to SARS-CoV-2 in 23 infants/young children. Antibody responses to SARS-CoV-2 spike antigens peaked approximat
Externí odkaz:
https://doaj.org/article/ed544dd2fbaf4305bcbd062470e7123a
Autor:
Rachel H. Bonami, Christina E. Thurman, Sonam Verma, Camille S. Westlake, Lindsay E. Nyhoff, Bridgette B. Barron, Andrea Reboldi, Peggy L. Kendall
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Bruton’s tyrosine kinase (Btk) deficiency preferentially eliminates autoreactive B cells while sparing normal humoral responses, but has not been studied in mucosal immunity. Commensal microbes and intact BTK signaling have been independently shown
Externí odkaz:
https://doaj.org/article/02d107f8b6104e819fad01d61a7841d3
Autor:
Robert C. Kauffman, Oluwaseyi Adekunle, Hanyi Yu, Alice Cho, Lindsay E. Nyhoff, Meagan Kelly, Jason B. Harris, Taufiqur Rahman Bhuiyan, Firdausi Qadri, Stephen B. Calderwood, Richelle C. Charles, Edward T. Ryan, Jun Kong, Jens Wrammert
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Immunity to the severe diarrheal disease cholera is largely mediated by lipopolysaccharide (LPS)-specific antibodies. However, the properties and protective mechanism of functionally relevant antibodies have not been well defined.
Externí odkaz:
https://doaj.org/article/8e0f934dff5f485db6acca027300e978
Autor:
Rajesh M. Valanparambil, Jennifer Carlisle, Susanne L. Linderman, Akil Akthar, Ralph Linwood Millett, Lilin Lai, Andres Chang, Ashley A. McCook-Veal, Jeffrey Switchenko, Tahseen H. Nasti, Manpreet Saini, Andreas Wieland, Kelly E. Manning, Madison Ellis, Kathryn M. Moore, Stephanie L. Foster, Katharine Floyd, Meredith E. Davis-Gardner, Venkata-Viswanadh Edara, Mit Patel, Conor Steur, Ajay K. Nooka, Felicia Green, Margaret A. Johns, Fiona O'Brein, Uma Shanmugasundaram, Veronika I. Zarnitsyna, Hasan Ahmed, Lindsay E. Nyhoff, Grace Mantus, Michael Garett, Srilatha Edupuganti, Madhusmita Behra, Rustom Antia, Jens Wrammert, Mehul S. Suthar, Madhav V. Dhodapkar, Suresh Ramalingam, Rafi Ahmed
Publikováno v:
Journal of Clinical Oncology. 40:3808-3816
PURPOSE To examine COVID-19 mRNA vaccine–induced binding and neutralizing antibody responses in patients with non–small-cell lung cancer (NSCLC) to SARS-CoV-2 614D (wild type [WT]) strain and variants of concern after the primary 2-dose and boost
Autor:
Rajesh M Valanparambil, Jennifer Carlisle, Susanne L. Linderman, Akil Akthar, Ralph Linwood Millett, Lilin Lai, Andres Chang, Ashley A. McCook, Jeffrey Switchenko, Tahseen H. Nasti, Manpreet Saini, Andreas Wieland, Kelly E. Manning, Madison Ellis, Kathryn M. Moore, Stephanie L. Foster, Katharine Floyd, Meredith E. Davis-Gardner, Venkata-Viswanadh Edara, Mit Patel, Conor Steur, Ajay K. Nooka, Felicia Green, Margaret A. Johns, Fiona O’Brein, Uma Shanmugasundaram, Veronika I Zarnitsyna, Hasan Ahmed, Lindsay E. Nyhoff, Grace Mantus, Michael Garett, Srilatha Edupuganti, Madhusmita Behra, Rustom Antia, Jens Wrammert, Mehul S. Suthar, Madhav V. Dhodapkar, Suresh Ramalingam, Rafi Ahmed
Publikováno v:
medRxiv
PurposeWe investigated SARS-CoV-2 mRNA vaccine-induced binding and live-virus neutralizing antibody response in NSCLC patients to the SARS-CoV-2 wild type strain and the emerging Delta and Omicron variants.Methods82 NSCLC patients and 53 healthy adul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269dbe266a03f81062c2c87605cb3b7d
https://doi.org/10.1101/2022.01.03.22268599
https://doi.org/10.1101/2022.01.03.22268599
Autor:
Venkata-Viswanadh Edara, Kelly E. Manning, Madison Ellis, Lilin Lai, Kathryn M. Moore, Stephanie L. Foster, Katharine Floyd, Meredith E. Davis-Gardner, Grace Mantus, Lindsay E. Nyhoff, Sarah Bechnak, Ghina Alaaeddine, Amal Naji, Hady Samaha, Matthew Lee, Laurel Bristow, Laila Hussaini, Caroline Rose Ciric, Phuong-Vi Nguyen, Matthew Gagne, Jesmine Roberts-Torres, Amy R. Henry, Sucheta Godbole, Arash Grakoui, Marybeth Sexton, Anne Piantadosi, Jesse J. Waggoner, Daniel C. Douek, Evan J. Anderson, Nadine Rouphael, Jens Wrammert, Mehul S. Suthar
Publikováno v:
bioRxiv
Cell Reports Medicine
Cell Reports Medicine
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant emerged in November 2021 and consists of several mutations within the spike. We use serum from mRNA-vaccinated individuals to measure neutralization activity against omi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a248fce715eaa9c656d1cf1e71dc6b44
https://doi.org/10.1101/2021.12.20.473557
https://doi.org/10.1101/2021.12.20.473557
Autor:
Matthew T. Stier, Adam C. Seegmiller, Holly C. Casanova, Dawn C. Newcomb, Lindsay E. Nyhoff, R. Stokes Peebles, K. Goleniewska, Ramkrishna Mitra, Peggy L. Kendall, Matthew V. Puccetti, Christine M. Eischen, Jian Zhang
Publikováno v:
J Immunol
IL-33 is an IL-1 family member protein that is a potent driver of inflammatory responses in both allergic and nonallergic disease. This proinflammatory effect is mediated primarily by extracellular release of IL-33 from stromal cells and binding of t
Autor:
Shivan N. Patel, Sarah Furth, Rafi Ahmed, Julie Czartoski, Maria P. Lemos, Kristen W. Cohen, Sivaram Gunisetty, Mehul S. Suthar, Grace Mantus, M. Juliana McElrath, Rustom Antia, James B O'Keefe, Srilatha Edupuganti, Stephen C. De Rosa, Katharine Floyd, Hasan Ahmed, Mohini P. Gharpure, Lindsay E. Nyhoff, Aneesh K. Mehta, Brittany Prigmore, David S. Stephens, Susanne L. Linderman, Evan J. Anderson, Kathy Stephens, Veronika I. Zarnitsyna, Venkata Viswanadh Edara, Lilin Lai, Carson Norwood, Jens Wrammert, Zoe Moodie, Rachael E. Whaley, Nadine Rouphael, Carl W. Davis
Publikováno v:
medRxiv
Cell Reports Medicine
Cell Reports Medicine
Ending the COVID-19 pandemic will require long-lived immunity to SARS-CoV-2. Here, we evaluate 254 COVID-19 patients longitudinally up to 8 months and find durable broad-based immune responses. SARS-CoV-2 spike binding and neutralizing antibodies exh
Autor:
Stephen B. Calderwood, Robert C. Kauffman, Oluwaseyi Adekunle, Jason B. Harris, Edward T. Ryan, Jun Kong, Taufiqur Rahman Bhuiyan, Lindsay E. Nyhoff, Meagan Kelly, Alice Cho, Jens Wrammert, Firdausi Qadri, Richelle C. Charles, Hanyi Yu
Publikováno v:
mBio
mBio, Vol 12, Iss 2 (2021)
mBio, Vol 12, Iss 2 (2021)
Immunity to the severe diarrheal disease cholera is largely mediated by lipopolysaccharide (LPS)-specific antibodies. However, the properties and protective mechanism of functionally relevant antibodies have not been well defined.
Vibrio cholera
Vibrio cholera
Bruton’s tyrosine kinase (Btk) deficiency preferentially eliminates autoreactive B cells while sparing normal humoral responses, but has not been studied in mucosal immunity. Commensal microbes are essential for arthritis in K/BxN mice, used here t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28f9c59ab3f0a42799869a7cbec25bdc
https://doi.org/10.1101/2021.03.10.434762
https://doi.org/10.1101/2021.03.10.434762