Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lindsay E. Kugler"'
Autor:
Lindsay E. Kugler, Kenneth W. Ng, Clark T. Hung, Gerard A. Ateshian, Christopher J. O’Conor, James L. Cook
Publikováno v:
Annals of Biomedical Engineering. 39:2491-2500
The purpose of the presented work is to examine the response of engineered cartilage to a transient, 2-week application of anabolic growth factors compared to continuous exposure in in vitro culture. Immature bovine chondrocytes were suspended in aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19307260b23a1ec65c151371066db20c
https://doi.org/10.1007/s10439-011-0356-8
https://doi.org/10.1007/s10439-011-0356-8
Publikováno v:
Osteoarthritis and Cartilage. 17:220-227
Summary Objective It was hypothesized that controlled, scaffold removal in engineered cartilage constructs would improve their collagen content and mechanical properties over time in culture. Design Preliminary experiments characterized the effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d517deda135ea977d4ae8e572ea36732
https://doi.org/10.1016/j.joca.2008.06.013
https://doi.org/10.1016/j.joca.2008.06.013
Autor:
Lindsay E. Kugler, Christopher J. O’Conor, Clark T. Hung, Kenneth W. Ng, Terri-Ann N. Kelly, J. G. DeFrancis, Mandy M.-Y. Ho, Gerard A. Ateshian
Publikováno v:
Amino Acids. 35:433-438
Increased amino acid supplementation (0.5 x, 1.0 x, and 5.0 x recommended concentrations or additional proline) was hypothesized to increase the collagen content in engineered cartilage. No significant differences were found between groups in matrix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e853445da3ad5b6086188f25d024a7b9
https://doi.org/10.1007/s00726-007-0583-3
https://doi.org/10.1007/s00726-007-0583-3
Publikováno v:
ASME 2007 Summer Bioengineering Conference.
Agarose has been used as a model scaffold for cartilage tissue engineering research due to its maintenance of chondrocyte phenotype, support of cartilage tissue development, and ability to transmit mechanical stimuli [1–4]. In a previous study, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e78fa9e57d1edac3ae35a551518c0e6
https://doi.org/10.1115/sbc2007-176558
https://doi.org/10.1115/sbc2007-176558
Publikováno v:
ASME 2007 Summer Bioengineering Conference.
Agarose has been used as an experimental scaffold for cartilage tissue engineering research due to its biocompatibility with chondrocytes, support of cartilage tissue development, and ability to transmit mechanical stimuli [1–3]. Tissue engineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78006cba06dad7880dede758b008916a
https://doi.org/10.1115/sbc2007-176523
https://doi.org/10.1115/sbc2007-176523
Autor:
Lauren Y. Statman, Kenneth W. Ng, Lindsay E. Kugler, Evan Y. Lin, Justin D. Saliman, Gerard A. Ateshian, Clark T. Hung, Sean B. Lo
Publikováno v:
Annals of biomedical engineering. 35(11)
Media supplementation with collagen hydrolysate was hypothesized to increase the collagen content in engineered cartilage. By d28, hydrolysate at 0.5 mg/mL increased type II collagen content and 1 mg/mL increased mechanical properties, total collagen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218324e584c660b84aaae5f2dd1d8a0f
https://pubmed.ncbi.nlm.nih.gov/17721729
https://pubmed.ncbi.nlm.nih.gov/17721729