Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Lindsay D Butcher"'
Autor:
Gerco den Hartog, Ranajoy Chattopadhyay, Amber Ablack, Emily H Hall, Lindsay D Butcher, Asima Bhattacharyya, Lars Eckmann, Paul R Harris, Soumita Das, Peter B Ernst, Sheila E Crowe
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005382 (2016)
Generation of reactive oxygen species (ROS) during infection is an immediate host defense leading to microbial killing. APE1 is a multifunctional protein induced by ROS and after induction, protects against ROS-mediated DNA damage. Rac1 and NAPDH oxi
Externí odkaz:
https://doaj.org/article/70fcfad7834e4969a1e7f0b936341600
Autor:
Arwa S Kathiria, Lindsay D Butcher, Linda A Feagins, Rhonda F Souza, C Richard Boland, Arianne L Theiss
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31231 (2012)
Autophagy is an adaptive response to extracellular and intracellular stress by which cytoplasmic components and organelles, including damaged mitochondria, are degraded to promote cell survival and restore cell homeostasis. Certain genes involved in
Externí odkaz:
https://doaj.org/article/27768fd276f547c6a2adca76bb1a8057
Autor:
Gerco den Hartog, Lindsay D. Butcher, Amber L. Ablack, Laura A. Pace, Jailal N. G. Ablack, Richard Xiong, Soumita Das, Thaddeus S. Stappenbeck, Lars Eckmann, Peter B. Ernst, Sheila E. Crowe
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Pathogenic intestinal bacteria lead to significant disease in humans. Here we investigated the role of the multifunctional protein, Apurinic/apyrimidinic endonuclease 1 (APE1), in regulating the internalization of bacteria into the intestinal epithel
Externí odkaz:
https://doaj.org/article/909a51ee968d491cb7336a83d534599b
Autor:
Sean J. Lund, Kathryn A. Patras, Jacqueline M. Kimmey, Asami Yamamura, Lindsay D. Butcher, Pamela G.B. Del Rosario, Gilberto E. Hernandez, Alyssa M. McCoy, Omar Lakhdari, Victor Nizet, Lawrence S. Prince
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101207- (2020)
Summary: Streptococcus agalactiae (Group B Streptococcus, GBS) is the most common neonatal pathogen. However, the cellular and molecular mechanisms for neonatal susceptibility to GBS pneumonia and sepsis are incompletely understood. Here we optimized
Externí odkaz:
https://doaj.org/article/08a3b66fdb2f440388d8fc7d11f6b5fb
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 3, Pp 316-322 (2017)
Helicobacter pylori is a gram-negative, microaerophilic bacterium that infects the stomach and can lead to, among other disorders, the development of gastric cancer. The inability of the host to clear the infection results in a chronic inflammatory s
Externí odkaz:
https://doaj.org/article/01b2d6531b9d4901b33eb7c831d86af2
Autor:
Alex W. Tong, Marvin J. Stone, Joseph Newman, Joe Kansopon, Dongkun Chang, Reuben Hernandez-Alcoceba, Lindsay D. Butcher, Erica M. Gomes, Margret S. Fernandes
Supplementary Data from Growth Inhibition of Human Multiple Myeloma Cells by an Oncolytic Adenovirus Carrying the CD40 Ligand Transgene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4725954a492ce6a0fd9260c3b7d9e66e
https://doi.org/10.1158/1078-0432.22440796.v1
https://doi.org/10.1158/1078-0432.22440796.v1
Autor:
Alex W. Tong, Marvin J. Stone, Joseph Newman, Joe Kansopon, Dongkun Chang, Reuben Hernandez-Alcoceba, Lindsay D. Butcher, Erica M. Gomes, Margret S. Fernandes
Purpose: The growth-inhibitory activity of recombinant CD40 ligand (CD40L) is well documented in human multiple myeloma (MM). We examined MM-targeted delivery of CD40L by a conditional replicative oncolytic adenovirus, AdEHCD40L.Experimental Design:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e57faa45f585d750bb8a95ceda141f6
https://doi.org/10.1158/1078-0432.c.6518071
https://doi.org/10.1158/1078-0432.c.6518071
Autor:
Alyssa M. McCoy, Omar Lakhdari, Sayane Shome, Kaitlin Caoili, Gilberto E. Hernandez, Nima Aghaeepour, Lindsay D. Butcher, Kathleen Fisch, Lawrence S. Prince
Publikováno v:
Development. 150
Members of the Sp family of transcription factors regulate gene expression via binding GC boxes within promoter regions. Unlike Sp1, which stimulates transcription, the closely related Sp3 can either repress or activate gene expression and is require
Autor:
David Rios-Covian, Lindsay D. Butcher, Amber L. Ablack, Gerco den Hartog, Mason T. Matsubara, Hong Ly, Andrew W. Oates, Guorong Xu, Kathleen M. Fisch, Eric T. Ahrens, Shusuke Toden, Corrie C. Brown, Kenneth Kim, Dzung Le, Lars Eckmann, Bithika Dhar, Tadahide Izumi, Peter B. Ernst, Sheila E. Crowe
While best known for its role in oxidative DNA damage repair, apurinic-apyrimidinic endonuclease-1 (APE1) is a multifunctional protein that regulates multiple host responses during oxidative stress including the reductive activation of transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe004c4f6c31b2bf57a0dc06964a1723
http://hdl.handle.net/10029/625917
http://hdl.handle.net/10029/625917
Autor:
David, Rios-Covian, Lindsay D, Butcher, Amber L, Ablack, Gerco, den Hartog, Mason T, Matsubara, Hong, Ly, Andrew W, Oates, Guorong, Xu, Kathleen M, Fisch, Eric T, Ahrens, Shusuke, Toden, Corrie C, Brown, Kenneth, Kim, Dzung, Le, Lars, Eckmann, Bithika, Dhar, Tadahide, Izumi, Peter B, Ernst, Sheila E, Crowe
Publikováno v:
Antioxidantsredox signaling.