Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lindsay Crickard"'
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48706 (2012)
Smallpox (variola virus) is a bioweapon concern. Monkeypox is a growing zoonotic poxvirus threat. These problems have resulted in extensive efforts to develop potential therapeutics that can prevent or treat potentially lethal poxvirus infections in
Externí odkaz:
https://doaj.org/article/dfc9291f762349f6927efd0481dfcd83
Autor:
David Neul, Andrew Morse, Joel Renick, Brittany Masatsugu, Chi Ching Mak, James T. Limberis, Dany Gitnick, Zachary W. Yoder, Michael R. Kennedy, Kiev S. Ly, Samantha Sevidal, Richard Barido, Robert E. Petroski, Graeme Freestone, Clifford Cabebe, Jillian Basinger, Vincent J. Santora, Christine Hoffmaster, Chris L. Bellows, Yingzhuo Yan, Mi Chen, De Michael Chung, John Nikpur, Kristen Sebring, Jenny Wen, Ali Tabatabaei, Brett C. Bookser, Theresa A. Almos, Andrew Richard Hudson, J. Guy Breitenbucher, Chih-Kun Chai, Dong Lee, Lindsay Crickard, Anne Danks, Varsha Gupta, Marco Peters, Alan P. Kaplan, Jim Na, Nicola J. Broadbent, Stephine Chow, Douglas Zook
Publikováno v:
Journal of Medicinal Chemistry. 61:6018-6033
We report here the identification and optimization of a novel series of potent GlyT1 inhibitors. A ligand design campaign that utilized known GlyT1 inhibitors as starting points led to the identification of a novel series of pyrrolo[3,4- c]pyrazoles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3769bd94e72c5343ca6a4bb3a9739f64
https://doi.org/10.1021/acs.jmedchem.8b00372
https://doi.org/10.1021/acs.jmedchem.8b00372
Publikováno v:
Neurochemistry International. 129:104471
Phosphodiesterase (PDE) inhibition has been broadly investigated as a target for a wide variety of indications including central nervous system (CNS) disorders. Cyclic nucleotide (cNT) changes within associated tissues may serve as a biomarker of PDE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5ed6fcd40873cb9f7940efcb33d81a
https://doi.org/10.1016/j.neuint.2019.104471
https://doi.org/10.1016/j.neuint.2019.104471
Autor:
Lindsay Crickard, Guibao Gu, Kathe Stauber, Michael Chung, Doug Zook, Trevor Scott, Ali Tabatabaei, Jie Chen, Jef Vivian, Jenny Chen, Vinny Santora, Anne Danks, Yu-wen Li
Publikováno v:
Drug Metabolism and Pharmacokinetics. 34:S67
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb91914f5113ad5b7437fb897cf0d716
https://doi.org/10.1016/j.dmpk.2018.09.230
https://doi.org/10.1016/j.dmpk.2018.09.230
Autor:
Thomas Kaever, Lindsay Crickard, Michael H. Matho, Bjoern Peters, Xiangzhi Meng, Andrew Schlossman, Shane Crotty, Dirk M. Zajonc, Yan Xiang
Vaccinia virus (VACV) A27 is a target for viral neutralization and part of the Dryvax smallpox vaccine. A27 is one of the three glycosaminoglycan (GAG) adhesion molecules and binds to heparan sulfate. To understand the function of anti-A27 antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9332bfd87e8609c15c0b558cd9be2e9a
https://europepmc.org/articles/PMC4836320/
https://europepmc.org/articles/PMC4836320/
Autor:
Tomoyuki Tahara, Shinichiro Kato, Megan McCausland, Ralph T. Kubo, Shane Crotty, Mohammed Rafii-El-Idrissi Benhnia, Steven W. Granger, John Laudenslager, Lindsay Crickard, Lilia Koriazova
Publikováno v:
Antiviral therapy. 15(4)
Background Treatment of rare severe side effects of vaccinia virus (VACV) immunization in humans is currently very challenging. VACV possesses two immunologically distinct virion forms in vivo — intracellular mature virion (MV, IMV) and extracellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f53b12132e95d59450b92454693d8c
https://pubmed.ncbi.nlm.nih.gov/20587859
https://pubmed.ncbi.nlm.nih.gov/20587859
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 11, p e48706 (2012)
PLoS ONE, Vol 7, Iss 11, p e48706 (2012)
Smallpox (variola virus) is a bioweapon concern. Monkeypox is a growing zoonotic poxvirus threat. These problems have resulted in extensive efforts to develop potential therapeutics that can prevent or treat potentially lethal poxvirus infections in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4ae41415bfdd001830d09b1d2fe9e5
https://doi.org/10.1371/journal.pone.0048706
https://doi.org/10.1371/journal.pone.0048706
Autor:
Kaever, Thomas1, Matho, Michael H.2, Xiangzhi Meng3, Lindsay, Crickard1, Schlossman, Andrew2, Yan Xiang3, Crotty, Shane1,4, Peters, Bjoern1, Zajonc, Dirk M.2,5 dzajonc@liai.org
Publikováno v:
Journal of Virology. May2016, Vol. 90 Issue 9, p4334-4345. 12p.