Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lindsay C. Johnson"'
Autor:
Conor C. Lynch, Todd E. Peterson, Robert L. Vessella, Lindsay C. Johnson, Alexandre Bruni-Cardoso
Supplementary Data from Osteoclast-Derived Matrix Metalloproteinase-9 Directly Affects Angiogenesis in the Prostate Tumor–Bone Microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8559695f8b8a2769ce437d994630dfb4
https://doi.org/10.1158/1541-7786.22518678.v1
https://doi.org/10.1158/1541-7786.22518678.v1
Publikováno v:
2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC).
Introduction: Myocardial Perfusion Imaging (MPI) remains a cornerstone of cardiovascular care with 8 million scans per year in the US. Relative to current SPECT technology, cardiac PET has improved sensitivity and specificity and allows for dynamic i
Publikováno v:
Medical Physics. 45:2952-2963
PURPOSE: In traditional multi-pinhole SPECT systems, image multiplexing — the overlapping of pinhole projection images — may occur on the detector, which can inhibit quality image reconstructions due to photon-origin uncertainty. One proposed sys
Autor:
Daniel J. Rader, Lindsay C. Johnson, Stephen C. Moore, Marie A Guerraty, Scott D. Metzler, Eric Blankemeyer
Publikováno v:
J Nucl Cardiol
BACKGROUND: Despite growing interest in Coronary Microvascular Disease (CMVD), there is a dearth of mechanistic understanding. Mouse models offer opportunities to understand molecular processes in CMVD. We have sought to develop quantitative mouse im
Autor:
Zhe Liu, Stephen C. Moore, Morgan C. Lyon, Scott D. Metzler, James G. Westberg, Mi-Ae Park, Victor H. Lushear, Lindsay C. Johnson
Publikováno v:
Medical Physics. 43:6336-6346
Purpose: One approach to preclinical single-photon emission computed tomography (SPECT) imaging that provides both high resolution and high sensitivity is based on imaging a mouse inside a collimating tube; many magnified pinhole projection images fr
Publikováno v:
Physics in Medicine and Biology. 61:2003-2013
We are designing a dual-resolution pre-clinical SPECT system based on square-pinhole apertures for use in applications with a small field-of-view (FOV), such as cardiac imaging of mice. Square pinholes allow for increased sensitivity due to more effi
Publikováno v:
Physics in Medicine & Biology. 65:175001
Ischemic heart disease remains a significant public health concern, accentuating the importance of basic research and therapeutic studies of small animals in which myocardial changes can be reproducibly detected and quantified. Few or no studies have
Autor:
Scott D. Metzler, Wei Chang, Joel S. Karp, Dale Stentz, Lindsay C. Johnson, Poopalasingam Sankar
Publikováno v:
2018 IEEE Nuclear Science Symposium and Medical Imaging Conference Proceedings (NSS/MIC).
C-SPECT is a human cardiac SPECT system designed to acquire all necessary views for imaging simultaneously. The system uses slit-slat collimation focused on a cylindrical region with the capability of identifying the heart either through a scout or t
Publikováno v:
IEEE Transactions on Nuclear Science. 62:2036-2042
Advances in fabrication techniques, electronics, and mechanical cooling systems have given rise to germanium detectors suitable for biomedical imaging. We are developing a small-animal SPECT system that uses a double-sided Ge strip detector. The dete
Publikováno v:
2017 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC).
To assess myocardial blood flow (MBF) in mice, and subsequently coronary microvascular function, we have previously developed a non-invasive, in-vivo, dynamic cardiac imaging protocol using the U-SPECT+ system. This work investigates microSPECT quant