Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lindsay B. McKenna"'
Autor:
Mark J. Ferreira, Lindsay B. McKenna, Jia Zhang, Maximilian Reichert, Basil Bakir, Elizabeth L. Buza, Emma E. Furth, Clifford W. Bogue, Anil K. Rustgi, Klaus H. Kaestner
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 5, Pp 550-569 (2015)
Background & Aims: Perturbations in pancreatic ductal bicarbonate secretion cause chronic pancreatitis. The physiologic mechanism of ductal secretion is known, but its transcriptional control is not. We determine the role of the transcription factor
Externí odkaz:
https://doaj.org/article/13f8248f1d774c53929ed9a3b0f1912d
Autor:
Lindsay B. McKenna, Anil K. Rustgi, Klaus H. Kaestner, Elizabeth L. Buza, Maximilian Reichert, Jia Zhang, Emma E. Furth, Basil Bakir, Clifford W. Bogue, Mark J. Ferreira
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 5, Pp 550-569 (2015)
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 5, Pp 550-569 (2015)
Background & Aims: Perturbations in pancreatic ductal bicarbonate secretion cause chronic pancreatitis. The physiologic mechanism of ductal secretion is known, but its transcriptional control is not. We determine the role of the transcription factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4d47afb63231dc76bc343cd25e42e4
https://doi.org/10.1016/j.jcmgh.2015.06.007
https://doi.org/10.1016/j.jcmgh.2015.06.007
Autor:
Yan Gao, Lindsay B. McKenna, John Le Lay, Linda E. Greenbaum, Klaus H. Kaestner, Jonathan Schug
Publikováno v:
Nucleic Acids Research
MicroRNAs fine-tune the activity of hundreds of protein-coding genes. The identification of tissue-specific microRNAs and their promoters has been constrained by the limited sensitivity of prior microRNA quantification methods. Here, we determine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62bfe38f5ef7d797b461e472a52ee564
https://doi.org/10.1093/nar/gkq782
https://doi.org/10.1093/nar/gkq782
Publikováno v:
Journal of Biological Chemistry. 284:5936-5944
The hedgehog (Hh) signaling pathway is a key component of cross-talk during vertebrate gut development, involving endodermally secreted Sonic (Shh) and Indian hedgehog (Ihh) proteins that directly signal to adjacent mesoderm. Here we show that the cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6aaff18bd4bf65c2731169adf212daa
https://doi.org/10.1074/jbc.m808103200
https://doi.org/10.1074/jbc.m808103200
Autor:
Anastassios Vourekas, Jaime B. McKenna, Jonathan Schug, Lindsay B. McKenna, Klaus H. Kaestner, Nuria C. Bramswig, Joshua R. Friedman
Publikováno v:
Gastroenterology. 139:1654-1664.e1
BACKGROUND & AIMS: Whereas the importance of microRNA (miRNA) for the development of several tissues is well established, its role in the intestine is unknown. We aimed to quantify the complete miRNA expression profile of the mammalian intestinal muc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39fc471c229949e0b0c5ee9abcb23aaf
https://doi.org/10.1053/j.gastro.2010.07.040
https://doi.org/10.1053/j.gastro.2010.07.040
Publikováno v:
Gastroenterology. 136:A-66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41b335a5181206962a2a3b9835789baf
https://doi.org/10.1016/s0016-5085(09)60298-5
https://doi.org/10.1016/s0016-5085(09)60298-5
Autor:
Lindsay B. McKenna, Vasumathi Kameswaran, Jonathan Schug, Nuria C. Bramswig, Joshua R. Friedman, Klaus H. Kaestner, Kumar Vivek, Inchan Choi, Kyoung-Jae Won, Anastassios Vourekas, Nicholas J. Hand, Melinda Penn, Chengyang Liu, Ying Chen, Ali Naji
Publikováno v:
Cell Metabolism. (1):135-145
SummaryType 2 diabetes mellitus (T2DM) is a complex disease characterized by the inability of the insulin-producing β cells in the endocrine pancreas to overcome insulin resistance in peripheral tissues. To determine if microRNAs are involved in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8eb14c0388db10f4ab812e8776e9b2
Autor:
Sarmistha Mukherjee, Gabriel Walton, Nicholas J. Hand, Lindsay B. McKenna, Joshua R. Friedman, Zhongjie Shi, Yan Gao, Karen Markley, Jonathan Schug, Anastassios Vourekas, Vasumathi Kameswaran, Linda E. Greenbaum, Klaus H. Kaestner, Momo Nakagawa, Kow Essuman
Publikováno v:
BMC Genomics
Background Validation of physiologic miRNA targets has been met with significant challenges. We employed HITS-CLIP to identify which miRNAs participate in liver regeneration, and to identify their target mRNAs. Results miRNA recruitment to the RISC i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea66ced7e1d3f233a70999ced4b296a