Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lindsay A Broadfield"'
Autor:
Peter K Ward, Sara Roose, Mio Ayana, Lindsay A Broadfield, Peter Dahlberg, Narcis Kabatereine, Adama Kazienga, Zeleke Mekonnen, Betty Nabatte, Lieven Stuyver, Fiona Vande Velde, Sofie Van Hoecke, Bruno Levecke
Publikováno v:
PLoS ONE, Vol 19, Iss 10, p e0309816 (2024)
BackgroundManual screening of a Kato-Katz (KK) thick stool smear remains the current standard to monitor the impact of large-scale deworming programs against soil-transmitted helminths (STHs). To improve this diagnostic standard, we recently designed
Externí odkaz:
https://doaj.org/article/b36e22e1d5bf4f7e9670b77a8cee3328
Autor:
Lindsay A. Broadfield, Amna Saigal, Jake C. Szamosi, Joanne A. Hammill, Ksenia Bezverbnaya, Dongdong Wang, Jaya Gautam, Evangelia E. Tsakiridis, Fiorella Di Pastena, Jamie McNicol, Jianhan Wu, Saad Syed, James S.V. Lally, Amogelang R. Raphenya, Marie-Jose Blouin, Michael Pollak, Andrea Sacconi, Giovanni Blandino, Andrew G. McArthur, Jonathan D. Schertzer, Michael G. Surette, Stephen M. Collins, Jonathan L. Bramson, Paola Muti, Theodoros Tsakiridis, Gregory R. Steinberg
Publikováno v:
Molecular Metabolism, Vol 61, Iss , Pp 101498- (2022)
Background/Purpose: Type 2 diabetes and obesity increase the risk of developing colorectal cancer. Metformin may reduce colorectal cancer but the mechanisms mediating this effect remain unclear. In mice and humans, a high-fat diet (HFD), obesity and
Externí odkaz:
https://doaj.org/article/9fae3275a0774580a7ba65a044f50126
Autor:
Paula Mc Kenna, Lindsay A. Broadfield, Annik Willems, Serge Masyn, Theresa Pattery, Ruxandra Draghia-Akli
Publikováno v:
Expert Review of Vaccines. 22:243-255
Large-scale vaccination campaigns can benefit from using digital health tools, particularly in low- and middle-income countries (LMICs). Selecting the best tool to fit into a pre-existing digital landscape can be challenging. We conducted a narrative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f779a2e8da37720b708a5722f5d422
https://doi.org/10.1080/14760584.2023.2184091
https://doi.org/10.1080/14760584.2023.2184091
Autor:
Sarah-Maria Fendt, Katrien De Bock, Shinya Kuroda, Diego di Bernardo, Diether Lambrechts, Johannes V. Swinnen, Christophe M. Deroose, Chantal Mathieu, Adrian Liston, Thomas G.P. Grünewald, Jos van Pelt, Rebeca Alba Rubio, James Dooley, Jia Zeng, Jonas Dehairs, Joke Van Elsen, Juan Fernandez-Garcia, Roman Vangoitsenhoven, Bryan Holvoet, Miki Eto, Masashi Fujii, Suguru Fujita, Francesco Napolitano, Yasuaki Karasawa, Kim Vriens, Mélanie Planque, Koen Veys, Dorien Broekaert, Roberta Schmieder, João André Gonçalves Duarte, Lindsay A. Broadfield
This document contains supplemental figures 1-7 and detailed supplemental methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f44ebc09205b2e32761557565475e6
https://doi.org/10.1158/0008-5472.22430289.v1
https://doi.org/10.1158/0008-5472.22430289.v1
Autor:
Sarah-Maria Fendt, Katrien De Bock, Shinya Kuroda, Diego di Bernardo, Diether Lambrechts, Johannes V. Swinnen, Christophe M. Deroose, Chantal Mathieu, Adrian Liston, Thomas G.P. Grünewald, Jos van Pelt, Rebeca Alba Rubio, James Dooley, Jia Zeng, Jonas Dehairs, Joke Van Elsen, Juan Fernandez-Garcia, Roman Vangoitsenhoven, Bryan Holvoet, Miki Eto, Masashi Fujii, Suguru Fujita, Francesco Napolitano, Yasuaki Karasawa, Kim Vriens, Mélanie Planque, Koen Veys, Dorien Broekaert, Roberta Schmieder, João André Gonçalves Duarte, Lindsay A. Broadfield
Supplemental tables 1-10.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73115082b4a3a4a81d0ded6705f5c24e
https://doi.org/10.1158/0008-5472.22430286.v1
https://doi.org/10.1158/0008-5472.22430286.v1
Autor:
Sarah-Maria Fendt, Katrien De Bock, Shinya Kuroda, Diego di Bernardo, Diether Lambrechts, Johannes V. Swinnen, Christophe M. Deroose, Chantal Mathieu, Adrian Liston, Thomas G.P. Grünewald, Jos van Pelt, Rebeca Alba Rubio, James Dooley, Jia Zeng, Jonas Dehairs, Joke Van Elsen, Juan Fernandez-Garcia, Roman Vangoitsenhoven, Bryan Holvoet, Miki Eto, Masashi Fujii, Suguru Fujita, Francesco Napolitano, Yasuaki Karasawa, Kim Vriens, Mélanie Planque, Koen Veys, Dorien Broekaert, Roberta Schmieder, João André Gonçalves Duarte, Lindsay A. Broadfield
Hepatic fat accumulation is associated with diabetes and hepatocellular carcinoma (HCC). Here, we characterize the metabolic response that high-fat availability elicits in livers before disease development. After a short term on a high-fat diet (HFD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::066c5087b982f8287631b91a658df7f4
https://doi.org/10.1158/0008-5472.c.6513585.v1
https://doi.org/10.1158/0008-5472.c.6513585.v1
Autor:
Linda A. Villani, Brennan K. Smith, Katarina Marcinko, Rebecca J. Ford, Lindsay A. Broadfield, Alex E. Green, Vanessa P. Houde, Paola Muti, Theodoros Tsakiridis, Gregory R. Steinberg
Publikováno v:
Molecular Metabolism, Vol 5, Iss 10, Pp 1048-1056 (2016)
Objective: The sodium-glucose transporter 2 (SGLT2) inhibitors Canagliflozin and Dapagliflozin are recently approved medications for type 2 diabetes. Recent studies indicate that SGLT2 inhibitors may inhibit the growth of some cancer cells but the me
Externí odkaz:
https://doaj.org/article/b9f92a22e002499f9a6381410683e0c8
Autor:
Matteo Rossi, Patricia Altea-Manzano, Margherita Demicco, Ginevra Doglioni, Laura Bornes, Marina Fukano, Anke Vandekeere, Alejandro M. Cuadros, Juan Fernández-García, Carla Riera-Domingo, Cristina Jauset, Mélanie Planque, H. Furkan Alkan, David Nittner, Dongmei Zuo, Lindsay A. Broadfield, Sweta Parik, Antonino Alejandro Pane, Francesca Rizzollo, Gianmarco Rinaldi, Tao Zhang, Shao Thing Teoh, Arin B. Aurora, Panagiotis Karras, Ines Vermeire, Dorien Broekaert, Joke Van Elsen, Maximilian M. L. Knott, Martin F. Orth, Sofie Demeyer, Guy Eelen, Lacey E. Dobrolecki, Ayse Bassez, Thomas Van Brussel, Karl Sotlar, Michael T. Lewis, Harald Bartsch, Manfred Wuhrer, Peter van Veelen, Peter Carmeliet, Jan Cools, Sean J. Morrison, Jean-Christophe Marine, Diether Lambrechts, Massimiliano Mazzone, Gregory J. Hannon, Sophia Y. Lunt, Thomas G. P. Grünewald, Morag Park, Jacco van Rheenen, Sarah-Maria Fendt
Publikováno v:
Nature
Rossi, M, Altea-Manzano, P, Demicco, M, Doglioni, G, Bornes, L, Fukano, M, Vandekeere, A, Cuadros, A M, Fernández-García, J, Riera-Domingo, C, Jauset, C, Planque, M, Alkan, H F, Nittner, D, Zuo, D, Broadfield, L A, Parik, S, Pane, A A, Rizzollo, F, Rinaldi, G, Zhang, T, Teoh, S T, Aurora, A B, Karras, P, Vermeire, I, Broekaert, D, Elsen, J V, Knott, M M L, Orth, M F, Demeyer, S, Eelen, G, Dobrolecki, L E, Bassez, A, Brussel, T V, Sotlar, K, Lewis, M T, Bartsch, H, Wuhrer, M, Veelen, P V, Carmeliet, P, Cools, J, Morrison, S J, Marine, J C, Lambrechts, D, Mazzone, M, Hannon, G J, Lunt, S Y, Grünewald, T G P, Park, M, Rheenen, J V & Fendt, S M 2022, ' PHGDH heterogeneity potentiates cancer cell dissemination and metastasis ', Nature, vol. 605, no. 7911, pp. 747-753 . https://doi.org/10.1038/s41586-022-04758-2
Nature, 605(7911), 747-+. NATURE PORTFOLIO
Rossi, M, Altea-Manzano, P, Demicco, M, Doglioni, G, Bornes, L, Fukano, M, Vandekeere, A, Cuadros, A M, Fernández-García, J, Riera-Domingo, C, Jauset, C, Planque, M, Alkan, H F, Nittner, D, Zuo, D, Broadfield, L A, Parik, S, Pane, A A, Rizzollo, F, Rinaldi, G, Zhang, T, Teoh, S T, Aurora, A B, Karras, P, Vermeire, I, Broekaert, D, Elsen, J V, Knott, M M L, Orth, M F, Demeyer, S, Eelen, G, Dobrolecki, L E, Bassez, A, Brussel, T V, Sotlar, K, Lewis, M T, Bartsch, H, Wuhrer, M, Veelen, P V, Carmeliet, P, Cools, J, Morrison, S J, Marine, J C, Lambrechts, D, Mazzone, M, Hannon, G J, Lunt, S Y, Grünewald, T G P, Park, M, Rheenen, J V & Fendt, S M 2022, ' PHGDH heterogeneity potentiates cancer cell dissemination and metastasis ', Nature, vol. 605, no. 7911, pp. 747-753 . https://doi.org/10.1038/s41586-022-04758-2
Nature, 605(7911), 747-+. NATURE PORTFOLIO
Cancer metastasis requires the transient activation of cellular programs enabling dissemination and seeding in distant organs1. Genetic, transcriptional and translational heterogeneity contributes to this dynamic process2,3. Metabolic heterogeneity h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e5caca229c7c7298416a476ab4cc79
https://hdl.handle.net/1887/3480405
https://hdl.handle.net/1887/3480405
Autor:
James S. V. Lally, Lindsay A. Broadfield, Tammy Mathurin, Gregory R. Steinberg, Panayiotis G. Zacharidis, Evangelia E. Tsakiridis, Paola Muti, Theodoros Tsakiridis, Danitra Maharaj, Gabe Menjolian, Linda Villani, Marcia Smoke, Thomas J. Farrell, Katarina Marcinko
Publikováno v:
The Prostate. 79:489-497
Background Radiotherapy (RT) is a key therapeutic modality for prostate cancer (PrCa), but RT resistance necessitates dose-escalation, often causing bladder and rectal toxicity. Aspirin, a prodrug of salicylate (SAL), has been associated with improve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c300e67f2246c6177f0695e468b79b5c
https://doi.org/10.1002/pros.23755
https://doi.org/10.1002/pros.23755
Autor:
Matteo Rossi, Patricia Altea-Manzano, Margherita Demicco, Ginevra Doglioni, Laura Bornes, Marina Fukano, Anke Vandekeere, Alejandro M. Cuadros, Juan Fernández-García, Carla Riera-Domingo, Cristina Jauset, Mélanie Planque, H. Furkan Alkan, David Nittner, Dongmei Zuo, Lindsay A. Broadfield, Sweta Parik, Antonino Alejandro Pane, Francesca Rizzollo, Gianmarco Rinaldi, Tao Zhang, Shao Thing Teoh, Arin B. Aurora, Panagiotis Karras, Ines Vermeire, Dorien Broekaert, Joke Van Elsen, Maximilian M. L. Knott, Martin F. Orth, Sofie Demeyer, Guy Eelen, Lacey E. Dobrolecki, Ayse Bassez, Thomas Van Brussel, Karl Sotlar, Michael T. Lewis, Harald Bartsch, Manfred Wuhrer, Peter van Veelen, Peter Carmeliet, Jan Cools, Sean J. Morrison, Jean-Christophe Marine, Diether Lambrechts, Massimiliano Mazzone, Gregory J. Hannon, Sophia Y. Lunt, Thomas G. P. Grünewald, Morag Park, Jacco van Rheenen, Sarah-Maria Fendt
Publikováno v:
Nature. 609:E8-E8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::470c42f68aee97514279e50b49e85d70
https://doi.org/10.1038/s41586-022-05226-7
https://doi.org/10.1038/s41586-022-05226-7