Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration

Autor: Soo-Yon Rhee, Vici Varghese, Susan P. Holmes, Gert U. Van Zyl, Kim Steegen, Mark A. Boyd, David A. Cooper, Sabin Nsanzimana, Shanmugam Saravanan, Charlotte Charpentier, Tulio de Oliveira, Mary-Ann A. Etiebet, Federico Garcia, Dominique Goedhals, Perpetua Gomes, Huldrych F. Günthard, Raph L. Hamers, Christopher J Hoffmann, Gillian Hunt, Awachana Jiamsakul, Pontiano Kaleebu, Phyllis Kanki, Rami Kantor, Bernhard Kerschberger, Vincent C. Marconi, Jean D'amour Ndahimana, Nicaise Ndembi, Nicole Ngo-Giang-Huong, Casper Rokx, Maria M. Santoro, Jonathan M. Schapiro, Daniel Schmidt, Lillian Seu, Kim C.E. Sigaloff, Sunee Sirivichayakul, Lindiwe Skhosana, Henry Sunpath, Michele Tang, Chunfu Yang, Sergio Carmona, Ravindra K. Gupta, Robert W. Shafer

Publikováno v: EBioMedicine, Vol 18, Iss C, Pp 225-235 (2017)

Tenofovir disoproxil fumarate (TDF) genotypic resistance defined by K65R/N and/or K70E/Q/G occurs in 20% to 60% of individuals with virological failure (VF) on a WHO-recommended TDF-containing first-line regimen. However, the full spectrum of reverse

Externí odkaz: https://doaj.org/article/c8c4f508a28b4db2b1253f3f557db59d

High Risk Janus Kinase 2 V617F Allele Burden in a Seven-Year Cohort of Patients with Myeloproliferative Neoplasms

Autor: Lindiwe Skhosana, Tracey Wiggill, Moses Chatambudza, Irene Ketseoglou

Publikováno v: Clinical laboratory. 67(11)

BACKGROUND JAK2 V617F is the most common somatic mutation associated with the classical Philadelphia (Ph) chromosome negative myeloproliferative neoplasms (MPNs), which include essential thrombocythemia (ET), polycythemia vera (PV), and primary myelo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c3a77e8ed3743b71bb76109fb72ca4
https://pubmed.ncbi.nlm.nih.gov/34758219

Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration

Autor: Casper Rokx, David A. Cooper, Perpétua Gomes, Rami Kantor, Nicole Ngo-Giang-Huong, Ravindra K. Gupta, Kim C. E. Sigaloff, Charlotte Charpentier, Jean d’Amour Ndahimana, Henry Sunpath, Vincent C. Marconi, Vici Varghese, Daniel Schmidt, Pontiano Kaleebu, Christopher J. Hoffmann, Chunfu Yang, Sunee Sirivichayakul, Gert U. van Zyl, Sergio Carmona, Gillian Hunt, Susan Holmes, Jonathan M. Schapiro, Federico García, Bernhard Kerschberger, Shanmugam Saravanan, Robert W. Shafer, Awachana Jiamsakul, Mark A. Boyd, Huldrych F. Günthard, Maria Mercedes Santoro, Nicaise Ndembi, Tulio de Oliveira, Michele Tang, Lillian Seu, Phyllis J. Kanki, Dominique Goedhals, Lindiwe Skhosana, Sabin Nsanzimana, Kim Steegen, Mary Ann A. Etiebet, Soo-Yon Rhee, Raph L. Hamers

Publikováno v: EBioMedicine, Vol 18, Iss C, Pp 225-235 (2017)
Rhee, S Y, Varghese, V, Holmes, S P, Van Zyl, G U, Steegen, K, Boyd, M A, Cooper, D A, Nsanzimana, S, Saravanan, S, Charpentier, C, de Oliveira, T, Etiebet, M A A, Garcia, F, Goedhals, D, Gomes, P, Günthard, H F, Hamers, R L, Hoffmann, C J, Hunt, G, Jiamsakul, A, Kaleebu, P, Kanki, P, Kantor, R, Kerschberger, B, Marconi, V C, D'amour Ndahimana, J, Ndembi, N, Ngo-Giang-Huong, N, Rokx, C, Santoro, M M, Schapiro, J M, Schmidt, D, Seu, L, Sigaloff, K C E, Sirivichayakul, S, Skhosana, L, Sunpath, H, Tang, M, Yang, C, Carmona, S, Gupta, R K & Shafer, R W 2017, ' Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen : An International Collaboration ', EBioMedicine, vol. 18, pp. 225-235 . https://doi.org/10.1016/j.ebiom.2017.03.024
EBioMedicine
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
EBioMedicine, 18, 225-235. Elsevier BV
EBioMedicine, 18, 225-235. Elsevier

Tenofovir disoproxil fumarate (TDF) genotypic resistance defined by K65R/N and/or K70E/Q/G occurs in 20% to 60% of individuals with virological failure (VF) on a WHO-recommended TDF-containing first-line regimen. However, the full spectrum of reverse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12acbc77e73a3262268ba8ffcca2c96d
http://www.sciencedirect.com/science/article/pii/S2352396417301202

A serious parvovirus B19 genotype 2 infection not detected in a commercial PCR assay

Autor: Cynthia Firnhaber, Vibha Kana, Lindiwe Skhosana, Sergio Carmona, Inéz Rossouw, Shookdev L. Modi

Publikováno v: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology. 60(1)

Lack of appropriate diagnostic assays due to cost, limited infratructure and sometimes sophisticated skills canhamper the ability o make accurate diagnoses, severely limiting appropriate patient are. In addition, laboratory diagnostic tests are desig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828059cdd94c8944e49691146dae93a6
https://pubmed.ncbi.nlm.nih.gov/24589313