Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Lindie Schloms"'
Autor:
Lindie Schloms, Amanda C. Swart
Publikováno v:
Molecules, Vol 19, Iss 3, Pp 3681-3695 (2014)
Major rooibos flavonoids—dihydrochalcones, aspalathin and nothofagin, flavones—orientin and vitexin, and a flavonol, rutin, were investigated to determine their influence on the activity of adrenal steroidogenic enzymes, 3β-hydroxysteroid dehydr
Externí odkaz:
https://doaj.org/article/34da8d9b3af04472ac86804355e4523a
Publikováno v:
Molecules, Vol 18, Iss 11, Pp 13228-13244 (2013)
The biological significance of 11β-hydroxyandrostenedione (11OHA4) has eluded researchers for the past six decades. It is now known that 11OHA4 is biosynthesized in the androgen arm of the adrenal steroidogenesis pathway and subsequently metabolized
Externí odkaz:
https://doaj.org/article/52beece96129446292afdb8163f93ad4
Autor:
Amanda C. Swart, Lindie Schloms
Publikováno v:
Molecules
Molecules, Vol 19, Iss 3, Pp 3681-3695 (2014)
Molecules; Volume 19; Issue 3; Pages: 3681-3695
Molecules, Vol 19, Iss 3, Pp 3681-3695 (2014)
Molecules; Volume 19; Issue 3; Pages: 3681-3695
Major rooibos flavonoids—dihydrochalcones, aspalathin and nothofagin, flavones—orientin and vitexin, and a flavonol, rutin, were investigated to determine their influence on the activity of adrenal steroidogenic enzymes, 3β-hydroxysteroid dehydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c13a408d443a96b8787e66ef71e0f3c
https://doi.org/10.3390/molecules19033681
https://doi.org/10.3390/molecules19033681
Autor:
Jeanine L. Marnewick, Karl-Heinz Storbeck, Amanda C. Swart, Pieter Swart, Carine Smith, Lindie Schloms
Publikováno v:
Molecular Nutrition & Food Research. 58:537-549
cope To determine the effect of Rooibos (Aspalathus linearis) on glucocorticoid biosynthesis and inactivation in vivo and in vitro. Methods and results Ultra-performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) analyses of in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c425b923a18bf897738f507b2c9258a
https://doi.org/10.1002/mnfr.201300463
https://doi.org/10.1002/mnfr.201300463
Autor:
Karl-Heinz Storbeck, Donita Africander, Amanda C. Swart, Lindie Schloms, Liezl M. Bloem, Pieter Swart
Publikováno v:
Molecular and Cellular Endocrinology. 377:135-146
Adrenal C19 steroids, dehydroepiandrostenedione (DHEA(S)) and androstenedione (A4), play a critical role in castration resistant prostate cancer (CRPC) as they are metabolised to dihydrotestosterone (DHT), via testosterone (T), or via the alternate 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fad0e1e386b2a6c9b019bbdc4f228a
https://doi.org/10.1016/j.mce.2013.07.006
https://doi.org/10.1016/j.mce.2013.07.006
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 128:128-138
The steroid hormone output of the adrenal gland is crucial in the maintenance of hormonal homeostasis, with hormonal imbalances being associated with numerous clinical conditions which include, amongst others, hypertension, metabolic syndrome, cardio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a109f171d52e119ffb2700567848c4
https://doi.org/10.1016/j.jsbmb.2011.11.003
https://doi.org/10.1016/j.jsbmb.2011.11.003
Advances in the analytical methodologies: Profiling steroids in familiar pathways-challenging dogmas
Autor:
Pieter Swart, Therina du Toit, Liezl M. Bloem, Karl-Heinz Storbeck, Amanda C. Swart, Lindie Schloms
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 153
The comprehensive evaluation of the adrenal steroidogenic pathway, given its complexity, requires methodology beyond the standard techniques currently employed. Advances in LC-MS/MS, coupled with in vitro cell models that produce all the steroid meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ee788550431ebda4fbcff08624bed2
https://pubmed.ncbi.nlm.nih.gov/25869556
https://pubmed.ncbi.nlm.nih.gov/25869556
Publikováno v:
Molecules
Molecules, Vol 18, Iss 11, Pp 13228-13244 (2013)
Molecules, Vol 18, Iss 11, Pp 13228-13244 (2013)
The biological significance of 11β-hydroxyandrostenedione (11OHA4) has eluded researchers for the past six decades. It is now known that 11OHA4 is biosynthesized in the androgen arm of the adrenal steroidogenesis pathway and subsequently metabolized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2fe84c9d21d9129e5f7b55c28bf4a9e
https://pubmed.ncbi.nlm.nih.gov/24165582
https://pubmed.ncbi.nlm.nih.gov/24165582
Autor:
Amanda C. Swart, Pieter Swart, Karl-Heinz Storbeck, Liezl M. Bloem, Lindie Schloms, Therina du Toit, William E. Rainey, Jonathan L. Quanson
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 138
11β-Hydroxyandrostenedione (11OHA4), which is unique to the adrenal, was first isolated from human adrenal tissue in the fifties. It was later shown in the sixties that 11β-hydroxytestosterone (11OHT) was also produced by the human adrenal. Attenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937f28eb5d659a684bcf6803b245a0ac
https://pubmed.ncbi.nlm.nih.gov/23685396
https://pubmed.ncbi.nlm.nih.gov/23685396
Autor:
Carine Smith, Pieter Swart, M Roos, Lindie Schloms, Karl-Heinz Storbeck, Amanda C. Swart, Jeanine L. Marnewick
Publikováno v:
PharmaNutrition. 2:82-83
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::220d4255384d99c3a11056ab0b195427
https://doi.org/10.1016/j.phanu.2013.11.023
https://doi.org/10.1016/j.phanu.2013.11.023