Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lindice Mitie Nisimura"'
Autor:
Lindice Mitie Nisimura, Roberto Rodrigues Ferreira, Laura Lacerda Coelho, Gabriel Melo de Oliveira, Beatriz Matheus Gonzaga, Marcelo Meuser-Batista, Joseli Lannes-Vieira, Tania Araujo-Jorge, Luciana Ribeiro Garzoni
Publikováno v:
Biology, Vol 12, Iss 11, p 1414 (2023)
Chagas disease (CD) caused by Trypanosoma cruzi is a neglected illness and a major reason for cardiomyopathy in endemic areas. The existing therapy generally involves trypanocidal agents and therapies that control cardiac alterations. However, there
Externí odkaz:
https://doaj.org/article/fa3f9034331d4b4dab899d74e5e4e0ca
Autor:
Mariana Galvão Ferrarini, Lindice Mitie Nisimura, Richard Marcel Bruno Moreira Girard, Mayke Bezerra Alencar, Mariana Sayuri Ishikawa Fragoso, Carlla Assis Araújo-Silva, Alan de Almeida Veiga, Ana Paula Ressetti Abud, Sheila Cristina Nardelli, Rossiane C. Vommaro, Ariel Mariano Silber, Marie France-Sagot, Andréa Rodrigues Ávila
Publikováno v:
mSphere, Vol 6, Iss 1 (2021)
Currently, the drugs used for toxoplasmosis have severe toxicity to human cells, and the treatment still lacks effective and safer alternatives. The search for novel drug targets is timely.
Externí odkaz:
https://doaj.org/article/ab8bd52f627c4de5b2e487eb81926d12
Autor:
Lindice Mitie Nisimura, Vanessa Estato, Elen Mello de Souza, Patricia A Reis, Marcos Adriano Lessa, Hugo Caire Castro-Faria-Neto, Mirian Claudia de Souza Pereira, Eduardo Tibiriçá, Luciana Ribeiro Garzoni
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 7, p e2998 (2014)
Cardiomyopathy is the main clinical form of Chagas disease (CD); however, cerebral manifestations, such as meningoencephalitis, ischemic stroke and cognitive impairment, can also occur. The aim of the present study was to investigate functional micro
Externí odkaz:
https://doaj.org/article/5805a28f79a242b6a0cad6706d1d2138
Autor:
Gisele Tatiane Soares da Veiga, Rafael Amaral Donassolo, Sofia Forcellini, Julia Weber Ferraboli, Mario Antonio Kujbida Junior, Líndice Mitie Nisimura, Letícia Werzel Bassai, Rafael Luis Kessler, Mariana Serpeloni, Najara Carneiro Bittencourt, Yanka Evellyn Alves R. Salazar, Luiz Felipe Ferreira Guimarães, Jaime Louzada, Dayanne Kamylla Alves da Silva Barros, Stefanie Costa Pinto Lopes, Luzia Helena Carvalho, Tais Nóbrega de Sousa, Flora Satiko Kano, Fabio Trindade Maranhão Costa, Pryscilla Fanini Wowk, Letusa Albrecht
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Malaria represents a challenging global public health task, with Plasmodium vivax being the predominant parasite in Brazil and the most widely distributed species throughout the world. Developing a vaccine against P. vivax malaria demands innovative
Externí odkaz:
https://doaj.org/article/e9a1b407fbbe45ba8e14a9b258a7ae06
Autor:
Lindice Mitie Nisimura, Roberto Rodrigues Ferreira, Laura Lacerda Coelho, Elen Mello de Souza, Beatriz Matheus Gonzaga, Patrícia Mello Ferrão, Mariana Caldas Waghabi, Liliane Batista de Mesquita, Mirian Claudia de Souza Pereira, Otacilio da Cruz Moreira, Joseli Lannes-Vieira, Luciana Ribeiro Garzoni
Publikováno v:
Memórias do Instituto Oswaldo Cruz, Volume: 117, Article number: e220005, Published: 21 NOV 2022
BACKGROUND Angiogenesis has been implicated in tissue injury in several noninfectious diseases, but its role in Chagas disease (CD) physiopathology is unclear. OBJECTIVES The present study aimed to investigate the effect of Trypanosoma cruzi infectio
Autor:
Lindice Mitie Nisimura, Daniel Adesse, Pedro Henrique Victorino, Laura Lacerda Coelho, Paloma de Carvalho Vieira, Sanda Iacobas, Luciana Ribeiro Garzoni, Tatiana G. Melo, Dumitru A. Iacobas, Herbert B. Tanowitz, David C. Spray
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Chagas disease is responsible for more than 10,000 deaths per year and about 6 to 7 million infected people worldwide. In its chronic stage, patients can develop mega-colon, mega-esophagus, and cardiomyopathy. Differences in clinical outcomes may be
Autor:
Patrícia Mello Ferrão, Alanderson R. Nogueira, Otacilio C. Moreira, Julio A. Urbina, Lindice Mitie Nisimura, Mariana Caldas Waghabi, Luciana Ribeiro Garzoni, Marcelo Meuser-Batista
Publikováno v:
Molecular and biochemical parasitology. 238
Posaconazole (POS) is an inhibitor of ergosterol biosynthesis in clinical use for treating invasive fungal infections. POS has potent and selective anti-Trypanosoma cruzi activity and has been evaluated as a possible treatment for Chagas disease. Mic
Autor:
Beatriz Matheus de Souza Gonzaga, Líndice Mitie Nisimura, Laura Lacerda Coelho, Roberto Rodrigues Ferreira, Samuel Iwao Maia Horita, Daniela Gois Beghini, Vanessa Estato, Tania Cremonini de Araújo-Jorge, Luciana Ribeiro Garzoni
Publikováno v:
Biology, Vol 13, Iss 5, p 301 (2024)
Neurological commitment is a neglected manifestation of Chagas disease (CD). Meningoencephalitis mainly affects children and immunosuppressed patients, while stroke can occur with or without cardiac compromise. One of the possible causes of stroke de
Externí odkaz:
https://doaj.org/article/ae0ae991569a4d0e8c93559304118d36
Effect of benznidazole on cerebral microcirculation during acute Trypanosoma cruzi infection in mice
Autor:
Beatriz Matheus Souza Gonzaga, Samuel Iwao Maia Horita, Daniela Gois Beghini, Fabiana Gomes, Líndice Mitie Nisimura, Isabele Barbieri dos Santos, Vanessa Estato, Tania Cremonini de Araújo-Jorge, Luciana Ribeiro Garzoni
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Central nervous system alterations was described in Chagas disease in both human and experimental models, leading to meningoencephalitis, stroke and cognitive impairment. Recently, our group demonstrated that acute infection by Trypanossoma
Externí odkaz:
https://doaj.org/article/2767933348cc4777a42cb876751d588d
Autor:
Hugo C. Castro-Faria-Neto, Lindice Mitie Nisimura, Marcos Adriano Lessa, Luciana Ribeiro Garzoni, Elen Mello de Souza, Mirian Claudia de Souza Pereira, Patrícia A. Reis, Vanessa Estato, Eduardo Tibiriçá
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 7, p e2998 (2014)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Cardiomyopathy is the main clinical form of Chagas disease (CD); however, cerebral manifestations, such as meningoencephalitis, ischemic stroke and cognitive impairment, can also occur. The aim of the present study was to investigate functional micro