Enrichment of adeno-associated virus serotype 5 full capsids by anion exchange chromatography with dual salt elution gradients.

Autor: Lavoie RA; BridgeBio Gene Therapy LLC, Raleigh, North Carolina, USA., Zugates JT; Shattuck Labs, Durham, North Carolina, USA., Cheeseman AT; Cytiva, Marlborough, Massachusetts, USA., Teten MA; BridgeBio Gene Therapy LLC, Raleigh, North Carolina, USA., Ramesh S; BridgeBio Gene Therapy LLC, Raleigh, North Carolina, USA., Freeman JM; BridgeBio Gene Therapy LLC, Raleigh, North Carolina, USA., Swango S; BridgeBio Gene Therapy LLC, Raleigh, North Carolina, USA., Fitzpatrick J; BridgeBio Gene Therapy LLC, Raleigh, North Carolina, USA., Joshi A; BridgeBio Gene Therapy LLC, Raleigh, North Carolina, USA., Hollers B; KBI Biopharma, Durham, North Carolina, USA., Debebe Z; Shattuck Labs, Durham, North Carolina, USA., Lindgren TK; BridgeBio Gene Therapy LLC, Raleigh, North Carolina, USA., Kozak AN; BridgeBio Gene Therapy LLC, Raleigh, North Carolina, USA., Kondeti VK; BridgeBio Gene Therapy LLC, Raleigh, North Carolina, USA., Bright MK; BridgeBio Gene Therapy LLC, Raleigh, North Carolina, USA., Yearley EJ; BridgeBio Gene Therapy LLC, Raleigh, North Carolina, USA., Tracy A; Code Biotherapeutics, Hatfield, Pennsylvania, USA., Irwin JA; BridgeBio Gene Therapy LLC, Raleigh, North Carolina, USA., Guerrero M; BridgeBio Gene Therapy LLC, Raleigh, North Carolina, USA.

Publikováno v: Biotechnology and bioengineering [Biotechnol Bioeng] 2023 Oct; Vol. 120 (10), pp. 2953-2968. Date of Electronic Publication: 2023 May 31.