Signal requirement for cortical potential of transplantable human neuroepithelial stem cells.

Autor: Varga BV; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada. bv243@cam.ac.uk.; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Puddicombe Way, Cambridge, UK. bv243@cam.ac.uk., Faiz M; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.; Department of Surgery, Institute of Medical Science, University of Toronto, Toronto, ON, Canada., Pivonkova H; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Puddicombe Way, Cambridge, UK., Khelifi G; Cancer Research Center, Université Laval, Quebec City, QC, Canada.; CHU of Québec-Université Laval Research Center, Oncology Division, Quebec City, QC, Canada., Yang H; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada., Gao S; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada., Linderoth E; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada., Zhen M; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada., Karadottir RT; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Puddicombe Way, Cambridge, UK.; Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Hussein SM; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.; Cancer Research Center, Université Laval, Quebec City, QC, Canada.; CHU of Québec-Université Laval Research Center, Oncology Division, Quebec City, QC, Canada., Nagy A; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada. nagy@lunenfeld.ca.; Department of Obstetrics and Gynaecology, and Institute of Medical Science, University of Toronto, Toronto, ON, Canada. nagy@lunenfeld.ca.; Australian Regenerative Medicine Institute, Monash University, Melbourne, VIC, Australia. nagy@lunenfeld.ca.

Publikováno v: Nature communications [Nat Commun] 2022 May 23; Vol. 13 (1), pp. 2844. Date of Electronic Publication: 2022 May 23.

The role of Ack1 in TRAIL receptor signalling

Autor: Linderoth, E.

The Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is one of the most recently identified death inducing ligands of the TNF cytokine family. TRAIL induces apoptosis in most cancer cells, whereas the majority of normal cells are resi

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625936

Pathway analysis of peripheral blood CD8+ T cell transcriptome shows differential regulation of sphingolipid signaling in multiple sclerosis and glioblastoma.

Autor: Stefanović, Milan¹ (AUTHOR), Jovanović, Ivan¹ (AUTHOR), Živković, Maja¹ (AUTHOR), Stanković, Aleksandra¹ (AUTHOR) alexas@vinca.rs

Publikováno v: PLoS ONE. 6/11/2024, Vol. 19 Issue 6, p1-17. 17p.

TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding.

Autor: Petrova PS; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Viller NN; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Wong M; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Pang X; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Lin GH; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Dodge K; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Chai V; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Chen H; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Lee V; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., House V; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Vigo NT; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Jin D; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Mutukura T; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Charbonneau M; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Truong T; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Viau S; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Johnson LD; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Linderoth E; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Sievers EL; Trillium Therapeutics Inc., Mississauga, Ontario, Canada., Maleki Vareki S; London Regional Cancer Program, London Health Sciences Centre, Lawson Heath Research Institute, London, Ontario, Canada.; Department of Oncology, University of Western Ontario, London, Ontario, Canada., Figueredo R; London Regional Cancer Program, London Health Sciences Centre, Lawson Heath Research Institute, London, Ontario, Canada.; Department of Oncology, University of Western Ontario, London, Ontario, Canada., Pampillo M; London Regional Cancer Program, London Health Sciences Centre, Lawson Heath Research Institute, London, Ontario, Canada., Koropatnick J; London Regional Cancer Program, London Health Sciences Centre, Lawson Heath Research Institute, London, Ontario, Canada.; Department of Oncology, University of Western Ontario, London, Ontario, Canada., Trudel S; Princess Margaret Cancer Center, University Health Network (UHN), Toronto, Ontario, Canada., Mbong N; Princess Margaret Cancer Center, University Health Network (UHN), Toronto, Ontario, Canada., Jin L; Princess Margaret Cancer Center, University Health Network (UHN), Toronto, Ontario, Canada., Wang JC; Princess Margaret Cancer Center, University Health Network (UHN), Toronto, Ontario, Canada.; Division of Medical Oncology and Hematology, Department of Medicine, UHN, and Department of Medicine, University of Toronto, Toronto, Ontario, Canada., Uger RA; Trillium Therapeutics Inc., Mississauga, Ontario, Canada. bob@trilliumtherapeutics.com.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2017 Feb 15; Vol. 23 (4), pp. 1068-1079. Date of Electronic Publication: 2016 Nov 17.

Intervention of AXL in EGFR Signaling via Phosphorylation and Stabilization of MIG6 in Non-Small Cell Lung Cancer.

Autor: Yang, Ya-Yu¹ (AUTHOR) irelandfish@nhri.edu.tw, Lin, Sheng-Chieh¹ (AUTHOR) jaysclin@gmail.com, Lay, Jong-Ding² (AUTHOR) jdlay@nutc.edu.tw, Cho, Chun-Yu¹ (AUTHOR) chunyu0116@nhri.edu.tw, Jang, Te-Hsuan^1,3 (AUTHOR) jang@nhri.edu.tw, Ku, Hsiu-Ying¹ (AUTHOR) shiuo@nhri.edu.tw, Yao, Chih-Jung^4,5 (AUTHOR) yao0928@tmu.edu.tw, Chuang, Shuang-En¹ (AUTHOR) sechuang@nhri.edu.tw

Publikováno v: International Journal of Molecular Sciences. Oct2023, Vol. 24 Issue 19, p14879. 16p.