Zobrazeno 1 - 10
of 4 691
pro vyhledávání: '"Linden J"'
Autor:
Tomalika R. Ullah, Matt D. Johansen, Katherine R. Balka, Rebecca L. Ambrose, Linden J. Gearing, James Roest, Julian P. Vivian, Sunil Sapkota, W. Samantha N. Jayasekara, Daniel S. Wenholz, Vina R. Aldilla, Jun Zeng, Stefan Miemczyk, Duc H. Nguyen, Nicole G. Hansbro, Rajan Venkatraman, Jung Hee Kang, Ee Shan Pang, Belinda J. Thomas, Arwaf S. Alharbi, Refaya Rezwan, Meredith O’Keeffe, William A. Donald, Julia I. Ellyard, Wilson Wong, Naresh Kumar, Benjamin T. Kile, Carola G. Vinuesa, Graham E. Kelly, Olivier F. Laczka, Philip M. Hansbro, Dominic De Nardo, Michael P. Gantier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract TANK-binding kinase 1 (TBK1) is a key signalling component in the production of type-I interferons, which have essential antiviral activities, including against SARS-CoV-2. TBK1, and its homologue IκB kinase-ε (IKKε), can also induce pro-
Externí odkaz:
https://doaj.org/article/780fdb67fa074e35823aa88357231e9d
Publikováno v:
Journal of Intelligence, Vol 12, Iss 7, p 66 (2024)
The aim of this Special Issue was to put forward a multifaceted reflection on the relevance of perceptual experience in affecting and modeling various aspects of cognitive performance [...]
Externí odkaz:
https://doaj.org/article/a7a5726b2e844d87a7d3f334f17d1e52
Publikováno v:
Journal of Intelligence, Vol 12, Iss 4, p 42 (2024)
We tested predictions deriving from the “Pleasure-Interest Model of Aesthetic Liking” (PIA Model), whereby aesthetic preferences arise from two fluency-based processes: an initial automatic, percept-driven default process and a subsequent perceiv
Externí odkaz:
https://doaj.org/article/7bb4c421d2104f6787aa80848d0ebb24
Autor:
Beth H. Richardson, Linden J. Ball
Publikováno v:
Journal of Intelligence, Vol 12, Iss 3, p 28 (2024)
Metareasoning refers to processes that monitor and control ongoing thinking and reasoning. The “metareasoning framework” that was established in the literature in 2017 has been useful in explaining how monitoring processes during reasoning are se
Externí odkaz:
https://doaj.org/article/7d9e0c9238474ef0a164eba17ecd1a97
Autor:
Marion C Bichet, Jack Adderley, Laura Avellaneda-Franco, Isabelle Magnin-Bougma, Natasha Torriero-Smith, Linden J Gearing, Celine Deffrasnes, Cassandra David, Genevieve Pepin, Michael P Gantier, Ruby Cy Lin, Ruzeen Patwa, Gregory W Moseley, Christian Doerig, Jeremy J Barr
Publikováno v:
PLoS Biology, Vol 21, Iss 10, p e3002341 (2023)
There is a growing appreciation that the direct interaction between bacteriophages and the mammalian host can facilitate diverse and unexplored symbioses. Yet the impact these bacteriophages may have on mammalian cellular and immunological processes
Externí odkaz:
https://doaj.org/article/6f17943a39654ebdb9c37c01b6a2076b
Autor:
Rosa C Coldbeck-Shackley, Ornella Romeo, Sarah Rosli, Linden J Gearing, Jodee A Gould, San S Lim, Kylie H Van der Hoek, Nicholas S Eyre, Byron Shue, Sarah A Robertson, Sonja M Best, Michelle D Tate, Paul J Hertzog, Michael R Beard
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1010843 (2023)
The immunological surveillance factors controlling vulnerability of the female reproductive tract (FRT) to sexually transmitted viral infections are not well understood. Interferon-epsilon (IFNɛ) is a distinct, immunoregulatory type-I IFN that is co
Externí odkaz:
https://doaj.org/article/5466e29dbea44bb9bb2a994a75c3a117
BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation
Autor:
Andrew Keniry, Natasha Jansz, Linden J. Gearing, Iromi Wanigasuriya, Joseph Chen, Christian M. Nefzger, Peter F. Hickey, Quentin Gouil, Joy Liu, Kelsey A. Breslin, Megan Iminitoff, Tamara Beck, Andres Tapia del Fierro, Lachlan Whitehead, Andrew Jarratt, Sarah A. Kinkel, Phillippa C. Taberlay, Tracy Willson, Miha Pakusch, Matthew E. Ritchie, Douglas J. Hilton, Jose M. Polo, Marnie E. Blewitt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Female embryonic stem cells (ESCs) are the ideal model to study X chromosome inactivation (XCI) establishment; however, these cells are challenging to keep in culture. Here the authors create fluorescent ‘Xmas’ reporter mice as a renewable source
Externí odkaz:
https://doaj.org/article/55d8f97f36464af78639b6d7c2a5c371
Autor:
Wendy Dankers, Melissa Northcott, Taylah Bennett, Akshay D’Cruz, Rochelle Sherlock, Linden J. Gearing, Paul Hertzog, Brendan Russ, Iolanda Miceli, Sebastian Scheer, Maki Fujishiro, Kunihiro Hayakawa, Keigo Ikeda, Eric F. Morand, Sarah A. Jones
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
SLE is a systemic multi-organ autoimmune condition associated with reduced life expectancy and quality of life. Glucocorticoids (GC) are heavily relied on for SLE treatment but are associated with detrimental metabolic effects. Type 1 interferons (IF
Externí odkaz:
https://doaj.org/article/3505bf1850804a299c6894502a57d398
Autor:
Nollaig M. Bourke, Sharon L. Achilles, Stephanie U-Shane Huang, Helen E. Cumming, San S. Lim, Irene Papageorgiou, Linden J. Gearing, Ross Chapman, Suruchi Thakore, Niamh E. Mangan, Sam Mesiano, Paul J. Hertzog
Publikováno v:
JCI Insight, Vol 7, Iss 18 (2022)
Although published studies have demonstrated that IFN-ε has a crucial role in regulating protective immunity in the mouse female reproductive tract, expression and regulation of IFN-ε in the human female reproductive tract (hFRT) have not been char
Externí odkaz:
https://doaj.org/article/617002a4f4874767b54742108c6286e8
Autor:
Melissa Northcott, Linden J. Gearing, Julie Bonin, Rachel Koelmeyer, Alberta Hoi, Paul J. Hertzog, Eric F. Morand
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectivesThe analysis of gene module expression in SLE is emerging as a tool to identify active biological pathways, with the aim of developing targeted therapies for subsets of patients. Detailed information on the effect of immunosuppressants on g
Externí odkaz:
https://doaj.org/article/12e3786e48b141e0b7b5099a6b5d3f2d