Smooth muscle-specific deletion of Ccn2 causes severe aorta malformation and atherosclerosis.

Autor: Larsen JH; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Centre for Individualized Medicine in Arterial Diseases, Odense University Hospital, Odense, Denmark., Hegelund JS; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Pedersen MK; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Andersson CM; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Lindegaard CA; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Hansen DR; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Stubbe J; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Lindholt JS; Centre for Individualized Medicine in Arterial Diseases, Odense University Hospital, Odense, Denmark.; Department of Cardiothoracic and Vascular Surgery, Odense University Hospital, Odense, Denmark., Hansen CS; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Grentzmann A; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Bloksgaard M; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Jensen BL; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Rodriguez-Díez RR; Department of Cell Biology, Complutense University School of Medicine, Madrid, Spain., Ruiz-Ortega M; Cellular and Molecular Biology in Renal and Vascular Pathology Laboratory, IIS-Fundación Jiménez Díaz-Universidad Autónoma Madrid, Madrid, Spain., Albinsson S; Vascular Physiology Environment, Department of Experimental Medical Science, Lund University, Lund, Sweden., Pasterkamp G; Laboratory of Clinical Chemistry and Haematology, University Medical Center, Heidelberglaan 100, Utrecht, the Netherlands., Mokry M; Laboratory of Clinical Chemistry and Haematology, University Medical Center, Heidelberglaan 100, Utrecht, the Netherlands.; Cardiology, University Medical Center Utrecht, Heidelberglaan 100, the Netherlands., Leask A; College of Dentistry, University of Saskatoon, Saskatoon, SK, Canada., Goldschmeding R; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., Pilecki B; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Sorensen GL; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Pyke C; Novo Nordisk A/S, Måløv, Denmark., Overgaard M; Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark., Beck HC; Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark., Ketelhuth DFJ; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Rasmussen LM; Centre for Individualized Medicine in Arterial Diseases, Odense University Hospital, Odense, Denmark.; Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark., Steffensen LB; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Centre for Individualized Medicine in Arterial Diseases, Odense University Hospital, Odense, Denmark.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2024 Aug 21. Date of Electronic Publication: 2024 Aug 21.

Splice-Switching Antisense Oligonucleotides Correct Phenylalanine Hydroxylase Exon 11 Skipping Defects and Rescue Enzyme Activity in Phenylketonuria.

Autor: Martínez-Pizarro A; Centro de Biología Molecular Severo Ochoa UAM-CSIC, IUBM, CIBERER, IdiPaz, Universidad Autónoma de Madrid, Madrid, Spain., Álvarez M; Centro de Biología Molecular Severo Ochoa UAM-CSIC, IUBM, CIBERER, IdiPaz, Universidad Autónoma de Madrid, Madrid, Spain., Dembic M; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Lindegaard CA; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Castro M; Centro de Diagnóstico de Enfermedades Moleculares (CEDEM), CIBERER, IdiPaz, Universidad Autónoma de Madrid, Madrid, Spain., Richard E; Centro de Biología Molecular Severo Ochoa UAM-CSIC, IUBM, CIBERER, IdiPaz, Universidad Autónoma de Madrid, Madrid, Spain., Andresen BS; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Desviat LR; Centro de Biología Molecular Severo Ochoa UAM-CSIC, IUBM, CIBERER, IdiPaz, Universidad Autónoma de Madrid, Madrid, Spain.

Publikováno v: Nucleic acid therapeutics [Nucleic Acid Ther] 2024; Vol. 34 (3), pp. 134-142. Date of Electronic Publication: 2024 Apr 09.