Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Linde Buntinx"'
Autor:
Heleen Marynissen, Linde Buntinx, Dorien Bamps, Marleen Depre, Els Ampe, Anne Van Hecken, Kristin Gabriel, Steve Sands, Gabriel Vargas, Jan de Hoon
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 8, Pp 1968-1977 (2022)
Abstract Maxadilan, a potent vasodilator peptide, selectively activates the PAC1 receptor, a promising target for migraine therapy. Therefore, maxadilan has been suggested as a tool to study the pharmacodynamics (PDs) of PAC1 receptor antagonists. Th
Externí odkaz:
https://doaj.org/article/5f31137aa46647bc88467882c8d81c9b
UNLABELLED: A comparison was made between the established laser Doppler imaging (LDI) technique and the more recently developed laser speckle contrast imaging (LSCI) method to measure changes in capsaicin- and cinnamaldehyde-induced dermal blood flow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2dc5bd2ae09db48008507fc1d4c0d17
https://lirias.kuleuven.be/handle/123456789/646592
https://lirias.kuleuven.be/handle/123456789/646592
Autor:
Jan de Hoon, Cédric Draulans, Antoinette MaassenVanDenBrink, Vincent Geldhof, Steve Vermeersch, Emmanuel Lesaffre, Linde Buntinx, K. Ibrahimi, Pascal Frederiks
Publikováno v:
Cephalalgia, 37(12), 1164-1172. SAGE Publications Ltd
Background Migraine is much more common in females than in males, and occurrence is associated with changes in female sex hormones. Calcitonin gene-related peptide (CGRP) plays a key role in migraine, and variations in female sex hormones may affect
Publikováno v:
British Journal of Clinical Pharmacology. 83:603-611
Aim To develop a non-invasive, safe and reproducible target-engagement biomarker for future TRPA1 antagonists in healthy volunteers. Methods Dose Finding (n = 11): 3%, 10%, and 30% cinnamaldehyde (CA) and placebo (=vehicle) was topically applied on t
Autor:
Gisela M. Terwindt, Irene de Boer, Michel D. Ferrari, AH Stam, Ronald Zielman, Linde Buntinx, Eelco J.P. de Koning, Jan de Hoon, Iris van der Steen, Arn M. J. M. van den Maagdenberg
Publikováno v:
Neurology, 91(10), E956-E963
Neurology, 91(10), e956-e963. Lippincott Williams & Wilkins
Neurology, 91(10), e956-e963. Lippincott Williams & Wilkins
ObjectiveWe aimed to evaluate the role of endothelial-dependent and endothelial-independent vascular reactivity in retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) and cerebral autosomal dominant arteriopath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569cc73e3dd36425a10ca4b0f53a2c27
http://hdl.handle.net/1887/95795
http://hdl.handle.net/1887/95795
Publikováno v:
British Journal of Clinical Pharmacology. 80:992-1000
The efficacy of calcitonin gene-related peptide (receptor) (CGRP-(R)) blocking therapeutics in the treatment of acute migraine headache provided proof-of-concept for the involvement of CGRP in the pathophysiology of this disorder. One of the major hu
Publikováno v:
Frontiers in Pharmacology. 8
Publikováno v:
Frontiers in Pharmacology. 8
Publikováno v:
British journal of clinical pharmacology. 83(3)
To develop a non-invasive, safe and reproducible target-engagement biomarker for future TRPA1 antagonists in healthy volunteers.Dose finding (n = 11): 3%, 10%, and 30% cinnamaldehyde (CA) and placebo (= vehicle) was topically applied on the right for
Autor:
Laura Vangeel, Joris Vriens, Elisabeth A.M. Cornelissen, J. de Hoon, Michael Janssen, Linde Buntinx, Thomas Voets, Bart Morlion, Elena Levtchenko
Publikováno v:
Scientific Reports, 6
Scientific Reports
Scientific Reports
Cystinosis is a rare autosomal recessive disorder characterized by lysosomal cystine accumulation due to loss of function of the lysosomal cystine transporter (CTNS). The most common mutation in cystinosis patients of Northern Europe consists of a 57