Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Linda Yu Ling Lan"'
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Rapid growth of single-cell sequencing techniques enables researchers to investigate almost millions of cells with diverse properties in a single experiment. Meanwhile, it also presents great challenges for selecting representative samples from massi
Externí odkaz:
https://doaj.org/article/72718c0920874f6ab57093c80dfa57c9
Autor:
Lei Li, Haley L. Dugan, Christopher T. Stamper, Linda Yu-Ling Lan, Nicholas W. Asby, Matthew Knight, Olivia Stovicek, Nai-Ying Zheng, Maria Lucia Madariaga, Kumaran Shanmugarajah, Maud O. Jansen, Siriruk Changrob, Henry A. Utset, Carole Henry, Christopher Nelson, Robert P. Jedrzejczak, Daved H. Fremont, Andrzej Joachimiak, Florian Krammer, Jun Huang, Aly A. Khan, Patrick C. Wilson
Publikováno v:
Cell Reports: Methods, Vol 1, Iss 4, Pp 100056- (2021)
Summary: Multimodal advances in single-cell sequencing have enabled the simultaneous quantification of cell surface protein expression alongside unbiased transcriptional profiling. Here, we present LinQ-View, a toolkit designed for multimodal single-
Externí odkaz:
https://doaj.org/article/e699f72a78bd4f8aa796657f3bd5dcb7
Autor:
Fionna A Surette, Jenna J Guthmiller, Lei Li, Alexandria J Sturtz, Rahul Vijay, Rosemary L Pope, Brandon L McClellan, Angela D Pack, Ryan A Zander, Peng Shao, Linda Yu-Ling Lan, Daniel Fernandez-Ruiz, William R Heath, Patrick C Wilson, Noah S Butler
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009288 (2021)
Immunity against malaria depends on germinal center (GC)-derived antibody responses that are orchestrated by T follicular helper (TFH) cells. Emerging data show that the regulatory cytokine IL-10 plays an essential role in promoting GC B cell respons
Externí odkaz:
https://doaj.org/article/a3b5ae33d8a345c092abcc9b69246885
Autor:
Jenna Guthmiller, Linda Yu-Ling Lan, Lei Li, Carole Henry, Christopher Stamper, Henry Utset, Alec Freyn, Julianna Han, Olivia Stovicek, Jiaolong Wang, Nai-Ying Zheng, Min Huang, Haley Dugan, Micah Tepora, Xueyong Zhu, Yao-Qing Chen, Anna-Karin Palm, Dustin Shaw, Madhumanthi Loganathan, Benjamin Francis, Mia McNair, Philip Mead, Ian Wilson, Adolfo Garcia-Sastre, Raffael Nachbagauer, Peter Palese, Andrew Ward, Lynda Coughlan, Florian Krammer, Patrick Wilson
In a phase I clinical trial, the chimeric hemagglutinin (cHA) immunogen induced antibody responses against the conserved HA stalk domain. However, the landscape of the B cell specificities and subsets induced by this vaccine remain undetermined. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de79b74f725fd6cd48343f3ef38289c0
https://doi.org/10.21203/rs.3.rs-2600472/v1
https://doi.org/10.21203/rs.3.rs-2600472/v1
Autor:
Peter Palese, Anna-Karin E. Palm, Patrick C. Wilson, Marie Van der Wielen, Rahnuma Wahid, Michelle Dickey, Jeffrey T. Guptill, Rong Hai, Chris Gast, Haley L. Dugan, David I. Bernstein, Alicia Solórzano, Abdollah Naficy, Christopher T. Stamper, Monica M. McNeal, Raffael Nachbagauer, Min Gao, Emmanuel B. Walter, Linda Yu-Ling Lan, Randy A. Albrecht, Dustin G. Shaw, Florian Krammer, Micah E. Tepora, Jodi Feser, Heather Wenzel, Megan E Ermler, Jenna J. Guthmiller, D. Freeman, Bruce L Innis, Adolfo García-Sastre, Carine Claeys, Kristen N Buschle, Weina Sun, Teddy John Wohlbold, Carole Henry, Victoria Sutton, Francesco Berlanda-Scorza, Yao-Qing Chen
Publikováno v:
The Lancet. Infectious Diseases
The Lancet. Infectious diseases, vol 20, iss 1
The Lancet. Infectious diseases, vol 20, iss 1
Summary Background Influenza viruses cause substantial annual morbidity and mortality globally. Current vaccines protect against influenza only when well matched to the circulating strains. However, antigenic drift can cause considerable mismatches b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0aaf8f19fab8daf9145b012346dd89
http://europepmc.org/articles/PMC6928577
http://europepmc.org/articles/PMC6928577
Autor:
Jenna J. Guthmiller, Julianna Han, Henry A. Utset, Lei Li, Linda Yu-Ling Lan, Carole Henry, Christopher T. Stamper, Meagan McMahon, George O’Dell, Monica L. Fernández-Quintero, Alec W. Freyn, Fatima Amanat, Olivia Stovicek, Lauren Gentles, Sara T. Richey, Alba Torrents de la Peña, Victoria Rosado, Haley L. Dugan, Nai-Ying Zheng, Micah E. Tepora, Dalia J. Bitar, Siriruk Changrob, Shirin Strohmeier, Min Huang, Adolfo García-Sastre, Klaus R. Liedl, Jesse D. Bloom, Raffael Nachbagauer, Peter Palese, Florian Krammer, Lynda Coughlan, Andrew B. Ward, Patrick C. Wilson
Publikováno v:
Nature. 602(7896)
Broadly neutralizing antibodies that target epitopes of haemagglutinin on the influenza virus have the potential to provide near universal protection against influenza virus infection1. However, viral mutants that escape broadly neutralizing antibodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e10d9cda2bfa4c1726c29d4f4e39e4
https://pubmed.ncbi.nlm.nih.gov/34942633
https://pubmed.ncbi.nlm.nih.gov/34942633
Autor:
Linda Yu-Ling Lan, Robert Jedrzejczak, Christopher T. Stamper, Maria Lucia Madariaga, Siriruk Changrob, Florian Krammer, Matthew Knight, Lei Li, Aly A. Khan, Haley L. Dugan, Henry A. Utset, Nai-Ying Zheng, Kumaran Shanmugarajah, Maud O. Jansen, Carole Henry, Olivia Stovicek, Patrick C. Wilson, Nicholas Asby, Andrzej Joachimiak, Jun Huang, Christopher A. Nelson, Daved H. Fremont
Publikováno v:
Cell Reports: Methods, Vol 1, Iss 4, Pp 100056-(2021)
Summary: Multimodal advances in single-cell sequencing have enabled the simultaneous quantification of cell surface protein expression alongside unbiased transcriptional profiling. Here, we present LinQ-View, a toolkit designed for multimodal single-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4a6ffa1c7a4328bebe69adc75c22ec
http://www.sciencedirect.com/science/article/pii/S2667237521001041
http://www.sciencedirect.com/science/article/pii/S2667237521001041
Autor:
Christopher T. Stamper, Min Huang, Haley L. Dugan, Henry A. Utset, Jenna J. Guthmiller, Patrick C. Wilson, Florian Krammer, Julianna Han, Linda Yu-Ling Lan, Micah E. Tepora, Andrew B. Ward, Peter Palese, Siriruk Changrob, Nai-Ying Zheng, Jesse D. Bloom, Raffael Nachbagauer, Carole Henry, Olivia Stovicek, Shirin Strohmeier, Sara T. Richey, Li L, Lynda Coughlan, Adolfo García-Sastre, Dalia J. Bitar, Lauren E. Gentles
SummaryBroadly neutralizing antibodies against influenza virus hemagglutinin (HA) have the potential to provide universal protection against influenza virus infections. Here, we report a distinct class of broadly neutralizing antibodies targeting an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c917466d9dab820ce710a00d9d4ce230
https://doi.org/10.1101/2021.02.25.432905
https://doi.org/10.1101/2021.02.25.432905
Autor:
Angela D. Pack, Daniel Fernandez-Ruiz, Linda Yu-Ling Lan, Lei Li, Peng Shao, Patrick C. Wilson, Fionna A. Surette, Ryan Zander, Noah S. Butler, Rahul Vijay, William R. Heath, Brandon L. McClellan, Rosemary L. Pope, Alexandria J. Sturtz, Jenna J. Guthmiller
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009288 (2021)
PLoS Pathogens
PLoS Pathogens
Immunity against malaria depends on germinal center (GC)-derived antibody responses that are orchestrated by T follicular helper (TFH) cells. Emerging data show that the regulatory cytokine IL-10 plays an essential role in promoting GC B cell respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8747db51ef6ec23b80096080355d4a17
https://doaj.org/article/a3b5ae33d8a345c092abcc9b69246885
https://doaj.org/article/a3b5ae33d8a345c092abcc9b69246885
Autor:
Maria Lucia Madariaga, Siriruk Changrob, Haley L. Dugan, Christopher T. Stamper, Florian Krammer, Henry A. Utset, Patrick C. Wilson, Daved H. Fremont, Aly A. Khan, A. Joachimiak, Nicholas Asby, Li L, Christopher A. Nelson, Kumaran Shanmugarajah, Maud O. Jansen, Robert Jedrzejczak, Linda Yu-Ling Lan, Matthew Knight, Nai-Ying Zheng, Carole Henry, Olivia Stovicek, Jun Huang
Publikováno v:
SSRN Electronic Journal.
Single cell RNA sequencing is a powerful tool for characterizing the molecular and cellular heterogeneity of immune cells during their development and activation. Multimodal advances in single cell sequencing have enabled the simultaneous quantificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4696d6caedc8a15383203877770152db
https://doi.org/10.2139/ssrn.3797273
https://doi.org/10.2139/ssrn.3797273