Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Linda Y. Semmler"'
Autor:
Dmitry Tyrsin, Thomas Hünig, Sergey Chuvpilo, Thomas Bukur, John C. Castle, Ulrich Kalinke, Hartmut Hengel, Valesca Boisguerin, Paula Tabares, Alexey A. Matskevich, Linda Y. Semmler, Patrick Bartholomaeus, Paula S. Römer
Publikováno v:
The Journal of Immunology. 192:2091-2098
Following inconspicuous preclinical testing, the superagonistic anti-CD28 mAb TGN1412 was applied to six study participants who all developed a devastating cytokine storm. We verified that TGN1412 treatment of fresh PBMCs induced only moderate respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1463a5099e941bbf9a9d8bc8906bb7b9
https://doi.org/10.4049/jimmunol.1302461
https://doi.org/10.4049/jimmunol.1302461
Autor:
Linda Y. Semmler, Zoe Waibler, Ulrich Kalinke, Sabrina Weissmüller, Jan Müller-Berghaus, Stefan Christians
Publikováno v:
Blood. 119:6268-6277
TGN1412, a superagonistic CD28-specific antibody, was shown to require Fc-cross-linking or immobilization as a prerequisite to mediate T-cell proliferation and cytokine release in vitro. We used primary human umbilical vein endothelial cells (HUVECs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee3380df7ef2f7f6edd8bd9ed26d90e8
https://doi.org/10.1182/blood-2011-12-401083
https://doi.org/10.1182/blood-2011-12-401083