Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Linda W. Pickle"'
Publikováno v:
Frontiers in Public Health, Vol 5 (2017)
BackgroundAfter a period of increasing rates, lung cancer incidence is declining in the US for men and women. We investigated lung cancer rate patterns by gender, geographic location, and histologic subtype, and for total lung cancer (TLC), for the e
Externí odkaz:
https://doaj.org/article/bec90120af0845af9f292ec8846a84f8
Autor:
Francis P. Boscoe, Linda W. Pickle
Publikováno v:
Cartography and Geographic Information Science. 30:237-248
Choropleth maps are the most widely used map type for mapping rates, such as those involving disease, crime, and socioeconomic indicators. The essential step of choosing a geographic unit to map is often made in an ad hoc manner. Among the desirable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd57166a5145ce20893ec1d173203d88
https://doi.org/10.1559/152304003100011171
https://doi.org/10.1559/152304003100011171
Autor:
Wu Chang Yang, Hsiao Min Chung, Ming Derg Lai, Raymond L. Woosley, Ching Pu Chen, Zone Yuan Hou, Linda W. Pickle, Elaine T. Buchert
Publikováno v:
Clinical Pharmacology & Therapeutics. 59:411-417
Background The polymorphic metabolism of debrisoquin and sparteine by cytochrome P450IID6 (CYP2D6) is genetically determined. Determination of the CYP2D6 metabolic phenotype with conventional urine analytic methods is not feasible in anuric patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9266bb67fe02ae832745c191fcc281d8
https://doi.org/10.1016/s0009-9236(96)90109-5
https://doi.org/10.1016/s0009-9236(96)90109-5
Autor:
Joyce A. Goldstein, Nadia Sukhova, Linda W. Pickle, Raymond L. Woosley, James W. Harris, Jan Hewett, John D. Balian, David A. Flockhart
Publikováno v:
Clinical pharmacology and therapeutics. 57(6)
We compared omeprazole and mephenytoin as probes for the CYP2C19 metabolic polymorphism. Single oral doses of omeprazole (20 mg) or mephenytoin (100 mg) were administered at least 1 week apart to 167 healthy volunteers. Mephenytoin metabolism was mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c8d2f0631c19cf156cefe5f81db115
https://pubmed.ncbi.nlm.nih.gov/7781266
https://pubmed.ncbi.nlm.nih.gov/7781266
Autor:
Linda W. Pickle
Publikováno v:
Computing Science and Statistics ISBN: 9780387977195
Inspection of maps from the recently-published Atlases of U.S. Cancer Mortality 1,2 suggested that mortality rates for many cancer sites were becoming more geographically homogeneous over time. From 1950 to 1980 rates for the more common tumors (e.g.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8364894738f8297e53cc99651f5fe2e0
https://doi.org/10.1007/978-1-4612-2856-1_86
https://doi.org/10.1007/978-1-4612-2856-1_86
Publikováno v:
Clinical pharmacology and therapeutics. 49(4)
Debrisoquin oxidative phenotype is a determinant of pharmacologie response for many drugs. Poor and extensive metabolizers can be identified by the dextromethorphan metabolic ratio (dextromethorphan/ dextrorphan). We developed and tested a method to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b11016404b21f659d8165b3e311f0c
https://pubmed.ncbi.nlm.nih.gov/2015730
https://pubmed.ncbi.nlm.nih.gov/2015730
Autor:
Aimsley Weston, Gary M. Muschik, Linda W. Pickle, Neil E. Caporaso, Haleem J. Issaq, David J. Tollerud, Benjamin F. Trump, Seena C. Aisner, Margaret A. Tucker, Daina Buivys, Curtis C. Harris, James H. Resau, Robert N. Hoover, Richard B. Hayes, Laureen A. Green-Gallo
Publikováno v:
Journal of the National Cancer Institute. 82(15)
In a case-control study, we tested the hypothesis that the genetically determined ability to metabolize debrisoquine is related to risk of lung cancer. Overall, individuals who were extensive metabolizers of debrisoquine were at significantly greater
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72143ba135697cff67871e1455eb365d
https://pubmed.ncbi.nlm.nih.gov/2374172
https://pubmed.ncbi.nlm.nih.gov/2374172
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