Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Linda Vahdat"'
Autor:
Ensieh M. Poursani, Daniele Mercatelli, Prahlad Raninga, Jessica L. Bell, Federica Saletta, Felix V. Kohane, Daniel P. Neumann, Ye Zheng, Jourdin R. C. Rouaen, Toni Rose Jue, Filip T. Michniewicz, Piper Schadel, Erin Kasiou, Maria Tsoli, Giuseppe Cirillo, Shafagh Waters, Tyler Shai-Hee, Riccardo Cazzoli, Merryn Brettle, Iveta Slapetova, Maria Kasherman, Renee Whan, Fernando Souza-Fonseca-Guimaraes, Linda Vahdat, David Ziegler, John G. Lock, Federico M. Giorgi, KumKum Khanna, Orazio Vittorio
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Background Metastatic cancer cells exploit Epithelial-mesenchymal-transition (EMT) to enhance their migration, invasion, and resistance to treatments. Recent studies highlight that elevated levels of copper are implicated in cancer progressi
Externí odkaz:
https://doaj.org/article/b17391f9a29d4891bcdc6914896812f8
Autor:
Mark Robson, Christopher Klebanoff, David Knorr, Jeffrey Ravetch, Gabriela D’Andrea, Linda Vahdat
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/e93160e465164293a44bcbee0ef6eea6
Autor:
Lee Schwartzberg, Kristi McIntyre, Sharon Wilks, Shannon Puhalla, Joyce O’Shaughnessy, Erhan Berrak, Yaohua He, Linda Vahdat
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Eribulin mesylate is a nontaxane microtubule dynamics inhibitor approved for second-line (European Union) or third-line (United States) treatment of metastatic breast cancer. Two phase 2 single trials, evaluating first-line eribul
Externí odkaz:
https://doaj.org/article/c42fa45d907146e88afe1182f3d7ba9f
Autor:
Rebecca D. Kehm, John L. Hopper, Esther M. John, Kelly-Anne Phillips, Robert J. MacInnis, Gillian S. Dite, Roger L. Milne, Yuyan Liao, Nur Zeinomar, Julia A. Knight, Melissa C. Southey, Linda Vahdat, Naomi Kornhauser, Tessa Cigler, Wendy K. Chung, Graham G. Giles, Sue-Anne McLachlan, Michael L. Friedlander, Prue C. Weideman, Gord Glendon, Stephanie Nesci, kConFab Investigators, Irene L. Andrulis, Saundra S. Buys, Mary B. Daly, Mary Beth Terry
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-13 (2019)
Abstract Background The use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has been associated with reduced breast cancer risk, but it is not known if this association extends to women at familial or genetic risk. We examined the
Externí odkaz:
https://doaj.org/article/5da6d9e843624b0697b2e4db6ae0cbf5
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1887 (2021)
Copper plays a key role in cancer metastasis, which is the most common cause of cancer death. Copper depletion treatment with tetrathiomolybdate (TM) improved disease-free survival in breast cancer patients with high risk of recurrence in a phase II
Externí odkaz:
https://doaj.org/article/baaa161386994dfebd2d227710fbe01d
Autor:
Shira Yomtoubian, Sharrell B. Lee, Akanksha Verma, Franco Izzo, Geoffrey Markowitz, Hyejin Choi, Leandro Cerchietti, Linda Vahdat, Kristy A. Brown, Eleni Andreopoulou, Olivier Elemento, Jenny Chang, Giorgio Inghirami, Dingcheng Gao, Seongho Ryu, Vivek Mittal
Publikováno v:
Cell Reports, Vol 30, Iss 3, Pp 755-770.e6 (2020)
Summary: Epigenetic changes are increasingly being appreciated as key events in breast cancer progression. However, breast cancer subtype-specific epigenetic regulation remains poorly investigated. Here we report that EZH2 is a leading candidate of e
Externí odkaz:
https://doaj.org/article/dc5eae5543644a968ae0a2033cf31557
Autor:
Emily S. Bell, Pragya Shah, Noam Zuela-Sopilniak, Dongsung Kim, Alice-Anais Varlet, Julien L.P. Morival, Alexandra L. McGregor, Philipp Isermann, Patricia M. Davidson, Joshua J. Elacqua, Jonathan N. Lakins, Linda Vahdat, Valerie M. Weaver, Marcus B. Smolka, Paul N. Span, Jan Lammerding
Publikováno v:
Oncogene, 41, 4211-4230
Oncogene, 41, 36, pp. 4211-4230
Oncogene
Oncogene, 41, 36, pp. 4211-4230
Oncogene
Contains fulltext : 283431.pdf (Publisher’s version ) (Closed access) Aberrations in nuclear size and shape are commonly used to identify cancerous tissue. However, it remains unclear whether the disturbed nuclear structure directly contributes to
Autor:
Linda Vahdat, Vivek Mittal, Claudia Fischbach, Maureen E. Lane, J. David Warren, Richard Zelkowitz, Elnaz Aljom, Jessica Guillaume-Abraham, Alysia Wiener, Sarah Schneider, Veronica Fitzpatrick, Marta Vallee Cobham, Diana Donovan, Anne Moore, Tessa Cigler, Ellen Chuang, Bo Ri Seo, Eleni Nackos, Sharrell B. Lee, Maureen M. Ward, Naomi Kornhauser, Amy Willis, Nancy Chan
This section contains details of all mixed models utilized in the statistical analyses. The inferential tests performed in this paper necessitates a multiple comparisons adjustment, and details of the adjustment procedure is included in this section
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536d57768d74ce9163e53345aac22105
https://doi.org/10.1158/1078-0432.22464144.v1
https://doi.org/10.1158/1078-0432.22464144.v1
Autor:
Linda Vahdat, Vivek Mittal, Claudia Fischbach, Maureen E. Lane, J. David Warren, Richard Zelkowitz, Elnaz Aljom, Jessica Guillaume-Abraham, Alysia Wiener, Sarah Schneider, Veronica Fitzpatrick, Marta Vallee Cobham, Diana Donovan, Anne Moore, Tessa Cigler, Ellen Chuang, Bo Ri Seo, Eleni Nackos, Sharrell B. Lee, Maureen M. Ward, Naomi Kornhauser, Amy Willis, Nancy Chan
Purpose: Bone marrow–derived progenitor cells, including VEGFR2+ endothelial progenitor cells (EPCs) and copper-dependent pathways, model the tumor microenvironment. We hypothesized that copper depletion using tetrathiomolybdate would reduce EPCs i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f1b4248fe0bf537c457a3ff11dd98c
https://doi.org/10.1158/1078-0432.c.6525630
https://doi.org/10.1158/1078-0432.c.6525630
Autor:
Linda Vahdat, Vivek Mittal, Claudia Fischbach, Maureen E. Lane, J. David Warren, Richard Zelkowitz, Elnaz Aljom, Jessica Guillaume-Abraham, Alysia Wiener, Sarah Schneider, Veronica Fitzpatrick, Marta Vallee Cobham, Diana Donovan, Anne Moore, Tessa Cigler, Ellen Chuang, Bo Ri Seo, Eleni Nackos, Sharrell B. Lee, Maureen M. Ward, Naomi Kornhauser, Amy Willis, Nancy Chan
The top panel shows the reaction chemistry of established lysyl oxidase (LOX) activity assay. The bottom panel shows the Amplex Red/HRP-based LOX activity assay that detects LOX activity in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21814513f3e3461f912d9a3469fe992d
https://doi.org/10.1158/1078-0432.22464147
https://doi.org/10.1158/1078-0432.22464147