Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Linda Tomaskovic"'
Autor:
Sebastien Dropsit, Pieter F. W. Stouten, Linda Tomaskovic, Thierry Christophe, Ellen van der Aar, Maarten Gees, Luc Nelles, Mia Jans, Monica Borgonovi, Evelyne M. Quinton, Katja Conrath, Jan Van Der Schueren, Caroline Joannesse, Hans Kelgtermans, Martin James Inglis Andrews, Sebastien Laurent Xavier Martina, Oscar Mammoliti, Ann De Blieck, Steven Emiel Van Der Plas, Tom De Munck
Publikováno v:
Journal of Medicinal Chemistry. 61:1425-1435
Cystic fibrosis (CF) is caused by mutations in the gene for the cystic fibrosis transmembrane conductance regulator (CFTR). With the discovery of Ivacaftor and Orkambi, it has been shown that CFTR function can be partially restored by administering o
Autor:
Donatella Verbanac, Mihaela Perić, Mario Matijašić, Andrea Fajdetić, Linda Tomaskovic, Hana Čipčić Paljetak, Mirjana Bukvić
Publikováno v:
Current Topics in Medicinal Chemistry. 17:919-940
Macrolides, polyketide natural products, and their 15-membered semi-synthetic derivatives are composed of substituted macrocyclic lactone ring and used primarily as potent antibiotics. Recently their usefulness was extended to antimalarial and anti-i
Autor:
Dijana Pesic, Ivaylo Jivkov Elenkov, Antun Hutinec, Linda Tomaskovic, Sanja Koštrun, Mirjana Bukvić, Sulejman Alihodžić, Dinko Žiher, Gordon Saxty
This chapter will discuss the recent literature of macrocycles and drug-like property space moving beyond the rule of five (bRo5). Trends in chemical classes that fall within this definition are discussed and the impact of the latest technologies in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0773aeccbb559a31abb85103d691d875
https://doi.org/10.1016/bs.pmch.2018.01.002
https://doi.org/10.1016/bs.pmch.2018.01.002
Autor:
Steven E, Van der Plas, Hans, Kelgtermans, Tom, De Munck, Sébastien L X, Martina, Sébastien, Dropsit, Evelyne, Quinton, Ann, De Blieck, Caroline, Joannesse, Linda, Tomaskovic, Mia, Jans, Thierry, Christophe, Ellen, van der Aar, Monica, Borgonovi, Luc, Nelles, Maarten, Gees, Pieter, Stouten, Jan, Van Der Schueren, Oscar, Mammoliti, Katja, Conrath, Martin, Andrews
Publikováno v:
Journal of medicinal chemistry. 61(4)
Cystic fibrosis (CF) is caused by mutations in the gene for the cystic fibrosis transmembrane conductance regulator (CFTR). With the discovery of Ivacaftor and Orkambi, it has been shown that CFTR function can be partially restored by administering o
Publikováno v:
Structural Chemistry. 20:73-80
Nitration of α -resorcylic acid (3, 5-dihydroxybenzoic acid) to 3, 5-dihydroxy-2-nitrobenzoic acid (1) and 3, 5-dihydroxy-4-nitrobenzoic acid (2), their separation, and crystallization is described. Crystal structures of 1, 1 · 3H2O, and 2 were det
Autor:
Jasna Padovan, Linda Tomaskovic, Stribor Markovic, Milan Mesic, Hana Čipčić Paljetak, Mladen Mercep, Ines Glojnarić, Mihailo Banjanac, Barbara Stanić, Jovica Ralić, Vesna Munić, Oresta Makaruha Stegić, Marijana Komac, Vesna Eraković Haber, Boska Hrvacic
new concept in design of safe glucocorticoid therapy was introduced by conjugating potent glucocorticoid steroids with macrolides (macrolactonolides). These compounds were synthesized from various steroid 17β-carboxylic acids and 9a-N-(3-aminoalkyl)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef738a49ddc32a931c0b944f69099b06
https://www.zora.uzh.ch/id/eprint/76109/
https://www.zora.uzh.ch/id/eprint/76109/
Autor:
Sulejman Alihodžić, Denis Polančec, Marjorie A. Smith, Ivica Malnar, Vesna Eraković Haber, Michael Lee, Krunoslav Nujić, Daniela Belamarić, Linda Tomaskovic, Klaus Schneider
Publikováno v:
European journal of pharmacology. 677(1-3)
In addition to antibacterial activity, some macrolide antibiotics, such as azithromycin and clarithromycin, also exhibit anti- inflammatory properties in vitro and in vivo, although the targets and mechanism(s) of action remain unknown. The aim of th