Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Linda T. Archer"'
Autor:
Wesley Bales, Michael F. Wilson, Paulo R. Wunder, Linda T. Archer, Elvira Missako Doi, Daniel J. Brackett, Megan R. Lerner, Andre A. Kajdacsy-Balla
Publikováno v:
Shock. 5:357-361
In vitro, endotoxin primes polymorphonuclear leukocytes (PMNs) to respond with a greater oxidative burst. The purpose of the present study was to investigate the in vivo effect of a wide range of single endotoxin bolus doses using a rat model. PMNs w
Publikováno v:
Journal of Surgical Research. 56:60-66
The purpose of this study was to compare the pathophysiology of bacteremia produced by intravenous infusion of either a Gram-positive (Staphylococcus aureus) or a Gram-negative (Escherichia coli) organism. Conscious, unrestrained, instrumented rats r
Autor:
Adeboye O. Osunkoya, Chaitali Tophkhane, Xiaohe Yang, Shihe Yang, Ann D. Thor, Wesley Bales, Linda T. Archer
Publikováno v:
International Journal of Oncology.
Genistein is a soy isoflavone with anti-tumor properties. Genistein-induced apoptosis involves Bcl-2 down-regulation. However, overexpression of Bcl-2 in breast cancer has been associated with better prognosis and response to hormonal therapy. To exa
Autor:
Linda T. Archer, Bruce Benjamin, Michael F. Wilson, Lerner B. Hinshaw, Richard B. Passey, B K Beller-Todd, Dayl J. Flournoy
Publikováno v:
Annals of Surgery. 194:51-56
Early aggressive therapy with maintenance infusions of methylprednisolone sodium succinate and gentamicin sulfate significantly increases the probability for survival of baboons given LD100 Escherichia coli. The present study was designed to determin
Publikováno v:
Experimental Biology and Medicine. 152:529-534
Past studies reported by this laboratory have documented myocardial dysfunction and progressively developing hypoglycemia in canine endotoxin shock. The purpose of the present study was to determine the effects of glucose concentrations and insulin i
Publikováno v:
Experimental Biology and Medicine. 155:179-183
Dogs administered lethal injections of E. coli endotoxin or E. coli organisms develop systemic hypotension, hypoglycemia, and hepatosplanchnic dysfunction (1-4). Progressively decreasing blood glucose levels after endotoxin or E. coli administration
Autor:
Lerner B. Hinshaw, Linda T. Archer
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 48:533-541
The effects of ouabain and digoxin on systemic and cardiopulmonary circulations and the degree and site of vascular pooling were evaluated in this study. A major emphasis was placed on the relationship of dosage to responses observed. Experiments wer
Publikováno v:
Journal of Surgical Research. 15:417-428
The adverse combined effects of mesenteric ischemia and the subsequently precipitated lethal shock after restoration of mesenteric blood flow have implicated direct or indirect roles of the heart in the pathogenesis of shock. The present experiments
Publikováno v:
The Journal of surgical research. 21(3)
Progressively developing lethal hypoglycemia in dogs and baboons subjected to endotoxin or live E. coli shock has recently been reported by this laboratory. The purpose of the present study was to explore the possibility that accelerated glycolysis i
Publikováno v:
The Journal of surgical research. 25(4)
The use of corticosteroids has been intensively studied for the treatment of endotoxin shock; however, there still remains much controversy over their use. This study was designed to determine the therapeutic value of treatment with methylprednisolon