Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Linda Starnes"'
Autor:
Christopher J. Morris, Michael G. Rolf, Linda Starnes, Inmaculada C. Villar, Amy Pointon, Holly Kimko, Giovanni Y. Di Veroli
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Pharmaceutical companies routinely screen compounds for hemodynamics related safety risk. In vitro secondary pharmacology is initially used to prioritize compounds while in vivo studies are later used to quantify and translate risk to humans. This st
Externí odkaz:
https://doaj.org/article/8cc8e9c9676f413cbf55bed31991df2d
Autor:
Linda Starnes, Andrew Hall, Damla Etal, Anna-Lina Cavallo, Piotr Grabowski, John Gallon, Michelle Kha, Ryan Hicks, Amy Pointon
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Creation of disease models utilizing hiPSCs in combination with CRISPR/Cas9 gene editing enable mechanistic insights into differential pharmacological responses. This allows translation of efficacy and safety findings from a healthy to a diseased sta
Externí odkaz:
https://doaj.org/article/e132b887164947bbaa01aa31e0c55474
Autor:
Ryan Hicks, Linda Starnes, Ellinor Hornberg, Damla Etal, Amy Pointon, Marcello Maresca, Anna-Lina Cavallo, Caroline S. Hirst, Shailesh Kumar Gupta, Andrew R. Hall
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 99:106595
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9783933e5e61426ee6ee0e245974f0ea
https://doi.org/10.1016/j.vascn.2019.05.183
https://doi.org/10.1016/j.vascn.2019.05.183
Autor:
Bi-Tzen Juang, Andrei Goga, Noelle D. L'Etoile, Francesca Palladino, Chen Gu, Linda Starnes, Scott Kennedy
Publikováno v:
Cell
Cell, 2013, 154 (5), pp.10
Cell, vol 154, iss 5
Cell, 2013, 154 (5), pp.10
Cell, vol 154, iss 5
Most eukaryotic cells express small regulatory RNAs. The purpose of one class, the somatic endogenous siRNAs (endo-siRNAs), remains unclear. Here, we show that the endo-siRNA pathway promotes odor adaptation in C.elegans AWC olfactory neurons. In ada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b747bc2287622251dc56ddf80f2bba96