Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Linda Sjöstrand"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The proteasome-associated deubiquitinase USP14 is a potential drug target. Using an inducible USP14 knockout system in colon cancer cells, we found that USP14 depletion impedes cellular proliferation, induces cell cycle arrest, and leads to
Externí odkaz:
https://doaj.org/article/bbfcda857074439396abde41654e9f68
Autor:
Johannes Gubat, Karthik Selvaraju, Linda Sjöstrand, Dhananjay Kumar Singh, Maria V. Turkina, Bernhard Schmierer, Pierre Sabatier, Roman A. Zubarev, Stig Linder, Pádraig D’Arcy
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Dienone compounds have been demonstrated to display tumor-selective anti-cancer activity independently of the mutational status of TP53. Previous studies have shown that cell death elicited by this class of compounds is associated with inhibition of
Externí odkaz:
https://doaj.org/article/c542304d11884d70abca4115db443fcd
Autor:
Diego Colombo, Laura Gatti, Linda Sjöstrand, Nives Carenini, Matteo Costantino, Elisabetta Corna, Noemi Arrighetti, Marco Zuccolo, Michelandrea De Cesare, Stig Linder, Pádraig D'Arcy, Paola Perego
Publikováno v:
Biochemical Pharmacology. 197:114900
Deubiquitinases (DUBs) mediate the removal of ubiquitin from diverse proteins that participate in the regulation of cell survival, DNA damage repair, apoptosis and drug resistance. Previous studies have shown an association between activation of cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85528a347c65373d2aefaa6a956b4949
https://doi.org/10.1016/j.bcp.2021.114900
https://doi.org/10.1016/j.bcp.2021.114900