Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Linda Schwaigerlehner"'
Autor:
Anne Chouquet, Andrea J. Pinto, Julia Hennicke, Wai Li Ling, Isabelle Bally, Linda Schwaigerlehner, Nicole M. Thielens, Renate Kunert, Jean-Baptiste Reiser
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Immunoglobulins type-M (IgMs) are one of the first antibody classes mobilized during immune responses against pathogens and tumor cells. Binding to specific target antigens enables the interaction with the C1 complex which strongly activates the clas
Externí odkaz:
https://doaj.org/article/fd92bd410b3d444aa041d51ce9174efb
Autor:
Julia Hennicke, Linda Schwaigerlehner, Clemens Grünwald-Gruber, Isabelle Bally, Wai Li Ling, Nicole Thielens, Jean-Baptiste Reiser, Renate Kunert
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229992 (2020)
Recombinant production of IgM antibodies poses a special challenge due to the complex structure of the proteins and their not yet fully elucidated interactions with the immune effector proteins, especially the complement system. In this study, we pre
Externí odkaz:
https://doaj.org/article/3eeb23ce4856449388769410bb7ab5ec
Autor:
Andrea J. Pinto, Isabelle Bally, Wai Li Ling, Anne Chouquet, Nicole M. Thielens, Linda Schwaigerlehner, Renate Kunert, Jean-Baptiste Reiser, Julia Hennicke
Publikováno v:
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology, 2022, 10, pp.816275. ⟨10.3389/fbioe.2022.816275⟩
Frontiers in Bioengineering and Biotechnology, 2022, 10, pp.816275. ⟨10.3389/fbioe.2022.816275⟩
The Immunoglobulins type-M (IgMs) are one of the first antibody classes mobilized during immune responses against pathogens and tumor cells. Binding to specific target antigens enables the interaction with the C1 complex which strongly activates the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734b27e04fcb3aab4e9c44e713cbeaca
https://hal.archives-ouvertes.fr/hal-03442200
https://hal.archives-ouvertes.fr/hal-03442200
Autor:
Linda, Schwaigerlehner, Patrick, Mayrhofer, Matthias, Diem, Willibald, Steinfellner, Emma, Fenech, Chris, Oostenbrink, Renate, Kunert
Publikováno v:
Applied Microbiology and Biotechnology
The production potential of recombinant monoclonal antibody (mAb) expressing cell lines depends, among other factors, on the intrinsic antibody structure determined by the amino acid sequence. In this study, we investigated the influence of somatic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3280278ba24bae714f301157852c01f
https://pubmed.ncbi.nlm.nih.gov/31350616
https://pubmed.ncbi.nlm.nih.gov/31350616
Publikováno v:
Protein Engineering, Design & Selection, 31 (7-8)
Protein Engineering, Design and Selection
Protein Engineering, Design and Selection
Humanized monoclonal antibodies (mAbs) are among the most promising modern therapeutics, but defined engineering strategies are still not available. Antibody humanization often leads to a loss of affinity, as it is the case for our model antibody Ab2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73d1817b6049391912d1cbc75e2ee7b
Publikováno v:
New Biotechnology. 44:S66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6148a5a8526b3ffc19395b1f708134f9
https://doi.org/10.1016/j.nbt.2018.05.1214
https://doi.org/10.1016/j.nbt.2018.05.1214