Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Linda S. Von Tungeln"'
Autor:
Hongtao Yu, Huey-Min Hwang, Peter P. Fu, Linda S. Von Tungeln, Joanna Moody, Guor-Cheng Fang, Yuh-Shen Wu
Publikováno v:
International Journal of Molecular Sciences, Vol 3, Iss 9, Pp 1008-1018 (2002)
Abstract: Stereoselective metabolism of dibenzo[a,l]pyrene (DB[a,l]P), 2-chlorodibenzo[a,l]pyrene (2-Cl-DB[a,l]P) and 10-chlorodibenzo[a,l]pyrene (10-Cl-DB[a,l]P) by rat liver microsomes was studied and effects of the chloro substituent on the metabo
Externí odkaz:
https://doaj.org/article/fba077b385194e8f892deea75430ea87
Autor:
Linda S. Von Tungeln, Cristina C. Jacob, Greg R. Olson, Gonçalo Gamboa da Costa, Frederick A. Beland
Publikováno v:
Journal of environmental science and health. Part C, Toxicology and carcinogenesis. 39(3)
In 2007, dietary exposure to "scrap melamine' resulted in the death of a large number of cats and dogs, which was attributed to the formation of melamine cyanurate crystals in their kidneys. In this study, we investigated if changes in urinary pH cou
Autor:
Michelle Vanlandingham, Kathyayini V. Divi, Daniel Martineau, Jennifer E. Dwyer, Miriam C. Poirier, Alyssa L. Damon, Linda S. Von Tungeln, Rao L. Divi, Mehnaz Ali, Frederick A. Beland, Mona I. Churchwell, Guy Beauchamp
Publikováno v:
Environmental and Molecular Mutagenesis. 61:216-223
DNA adducts of carcinogenic polycyclic aromatic hydrocarbons (PAHs) play a critical role in the etiology of gastrointestinal tract cancers in humans and other species orally exposed to PAHs. Yet, the precise localization of PAH-DNA adducts in the gas
Autor:
Yuxi Li, Qiangen Wu, Xilin Li, Linda S. Von Tungeln, Frederick A. Beland, Dayton Petibone, Lei Guo, Patrick Cournoyer, Supratim Choudhuri, Si Chen
Publikováno v:
Food Chem Toxicol
Cannabidiol (CBD) is a major cannabinoid present in extracts of the plant Cannabis sativa (marijuana). While the therapeutic effects of CBD on epilepsy have been demonstrated, less is understood regarding its potential adverse effects. Recent studies
Autor:
Igor P. Pogribny, Nigel J. Walker, Frederick A. Beland, Daniel R. Doerge, Linda S. Von Tungeln, Greg R. Olson, M. Matilde Marques, Robert P. Felton, Maria C.B. Mendoza, Brett T. Thorn
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 99
Furan is a volatile organic chemical that is a contaminant in many common foods. Furan is hepatocarcinogenic in mice and rats; however, the risk to humans from dietary exposure to furan cannot be estimated accurately because the lowest tested dose of
Autor:
Michelle Vanlandingham, Linda S. Von Tungeln, Robert J. Mitkus, Richard A. Forshee, Frederick A. Beland, Steven A. Anderson, Million A. Tegenge
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 81
Squalene is a component of oil-in-water emulsion adjuvants developed for potential use in some influenza vaccines. The biodistribution of the squalene-containing emulsion adjuvant (AddaVax™) alone and as part of complete H5N1 vaccine was quantified
Autor:
Cristina C. Jacob, Linda S. Von Tungeln, Gonçalo Gamboa da Costa, Peter L. Goering, Ronald P. Brown, Qin Zhang
Publikováno v:
Toxicological Sciences. 129:1-8
Oral coexposure of rats to melamine (MEL) and cyanuric acid (CYA) results in a dose-dependent increase in the formation of MEL-CYA crystals in the kidney. The aim of this study was to determine if urinary biomarkers of acute kidney injury could be us
Autor:
Igor P. Pogribny, M. Matilde Marques, Linda S. Von Tungeln, Daniel R. Doerge, Igor Koturbash, Gonçalo Gamboa da Costa, William M. Witt, Frederick A. Beland
Publikováno v:
International Journal of Cancer. 131:2008-2015
Acrylamide is a high-volume industrial chemical, a component of cigarette smoke, and a product formed in certain foods prepared at high temperatures. Previously, we compared the extent of DNA adduct formation and mutations in B6C3F1/Tk mice treated n
Autor:
Gonçalo Gamboa da Costa, Linda S. Von Tungeln, Michelle Vanlandingham, Cristina C. Jacob, Frederick A. Beland
Publikováno v:
Toxicological Sciences. 126:317-324
The intentional adulteration of pet food with melamine and cyanuric acid has been implicated in the kidney failure and death of a large number of cats and dogs in the United States. Although individually these compounds present low toxicity in a rang
Autor:
Tong Zhou, Kellie A. Woodling, Linda S. Von Tungeln, Frederick A. Beland, Daniel R. Doerge, Kevin J. Greenlees
Publikováno v:
Food and Chemical Toxicology. 49:2530-2535
Tricaine methanesulfonate, a sedative for temporarily immobilizing fish, has a 21-day withdrawal time. Benzocaine has been proposed as an alternative sedative because a withdrawal period may not be required. Since benzocaine is known to induce methem