Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Linda S. Richardson"'
Autor:
D. A. Prevar, R M Chanock, Linda S. Richardson, Ena Camargo, Thomas J. Schnitzer, R. B. Belshe
Publikováno v:
Archives of Virology. 54:53-60
After exposure of the temperature sensitive ts-1 mutant of respiratory syncytial virus to the chemical mutagne, nitrosoguanidine (NG), 2 clones of virus were recovered which were more temperature sensitive and stable genetically than the ts-1 mutant.
Autor:
Robert M. Chanock, D. Lewis Sly, D. A. Prevar, Linda S. Richardson, William T. London, R. B. Belshe, Ena Camargo
Publikováno v:
Journal of Medical Virology. 3:101-110
Five temperature-sensitive (ts) mutants of respiratory syncytial (RS) virus (ts-1, ts-1 NG-1, ts-1 NG-16, ts-2, and ts-7), previously evaluated forinfectivity and virulence in chimpanzees and owl monkeys, were also assayed for in vivo genetic stabili
Autor:
Robert M. Chanock, Ena Camargo, William T. London, D. Lewis Sly, D. A. Prevar, Linda S. Richardson, Robert B. Belshe
Publikováno v:
Journal of Medical Virology. 2:45-59
Into 14 juvenile cebus monkeys that lacked serum antibodies for RS virus 10(8) plaque-forming units (pfu) of wild-type respiratory syncytial (RS) virus were inoculated transtracheally. Roentgenographic evidence of pneumonia developed in 13 of 14 infe
Autor:
R. B. Belshe, D. A. Prevar, Linda S. Richardson, Ena Camargo, Thomas J. Schnitzer, R M Chanock
Publikováno v:
Journal of Virology. 24:8-12
ts-2, a temperature-sensitive and plaque morphology mutant of respiratory syncytial virus and sole representative of complementation group B, was compared with members of the other complementation groups of respiratory syncytial virus (group A [ts-1]
Autor:
D. Lewis Sly, Linda S. Richardson, Ena Camargo, William T. London, D. A. Prevar, Robert M. Chanock, R. B. Belshe
Publikováno v:
Journal of Medical Virology. 3:91-100
Approximately 104 plaque-forming units (pfu) of five temperature-sensitive (ts) mutants of respiratory syncytial (RS) virus were administered intranasally to seronegative chimpanzees to evaluate their level of attenuation. When the ts-1 mutant was gi
Autor:
Linda S. Richardson, Janet S. Butel
Publikováno v:
International Journal of Cancer. 7:75-85
The properties of hamster cells containing SV40 tumor (T) antigen in the cytoplasm, rather than the nucleus, were determined. Eight cell lines were established from eight tumors induced by hamster embryo fibroblasts transformed in vitro by PARA (2cT)
Publikováno v:
Virology. 46:844-855
Four different simian cell lines transformed by complete or defective SV40 were found to exhibit a variation in susceptibility to superinfection by SV40; two lines were susceptible to complete SV40 virions, one was resistant to complete virus but sus
Autor:
Thomas J. Schnitzer, Douglas D. Richman, Robert M. Chanock, Brian R. Murphy, Susan B. Spring, Linda S. Richardson
Publisher Summary This chapter discusses the current approaches to viral immunoprophylaxis. Virulence is the result of the efficient functioning of a number of different steps in the replicative cycle. Interference with any of these can lead to reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1da75f95095ff7b5d86502a257310f2b
https://doi.org/10.1016/b978-0-12-522050-7.50021-6
https://doi.org/10.1016/b978-0-12-522050-7.50021-6
Autor:
W. T. London, D. A. Prevar, Ena Camargo, D L Sly, R M Chanock, Lorfeld Jh, R. B. Belshe, Linda S. Richardson
Publikováno v:
Journal of medical virology. 1(3)
Four species of nonhuman primates were inoculated intranasally with 10(3.1) to 10(3.7) plaque forming units (pfu) of respiratory syncytial (RS) virus. Adults squirrel monkeys and newborn rhesus monkeys became infected and shed small quantities (peak
An in vitro study was performed to define in greater detail those factors which favored the growth of the ts-1 mutant of respiratory syncytial virus under restrictive conditions and the emergence of genetically altered virus with decreased temperatur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0eb883e85e4b40b461cd97498fe63c6
https://europepmc.org/articles/PMC515434/
https://europepmc.org/articles/PMC515434/